Results 71 to 80 of about 531,184 (380)

Synaptic Release Potentiation at Aging Auditory Ribbon Synapses

open access: yesFrontiers in Aging Neuroscience, 2021
Age-related hidden hearing loss is often described as a cochlear synaptopathy that results from a progressive degeneration of the inner hair cell (IHC) ribbon synapses.
Thibault Peineau   +7 more
doaj   +1 more source

Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cells. [PDF]

open access: yes, 2005
Lipid raft membrane compartmentalization and membrane-associated guanylate kinase (MAGUK) family molecular scaffolds function in establishing cell polarity and organizing signal transducers within epithelial cell junctions and neuronal synapses. Here, we
Miceli, M Carrie   +5 more
core  

Accumulation of Dense Core Vesicles in Hippocampal Synapses Following Chronic Inactivity. [PDF]

open access: yes, 2018
The morphology and function of neuronal synapses are regulated by neural activity, as manifested in activity-dependent synapse maturation and various forms of synaptic plasticity.
Bi, Guo-Qiang   +4 more
core   +2 more sources

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

Ingredients, Processing, and Fermentation: Addressing the Organoleptic Boundaries of Plant-Based Dairy Analogues

open access: yesFoods, 2022
Consumer interest and research in plant-based dairy analogues has been growing in recent years because of increasingly negative implications of animal-derived products on human health, animal wellbeing, and the environment.
Aileen Pua   +5 more
doaj   +1 more source

A life dedicated to pharmacy [PDF]

open access: yes, 2015
The Synapse meets Mary Ann Sant Fournier presently President of the Malta Chamber of Pharmacists, and visiting Senior Lecturer at the Faculty of Medicine & Surgery, UOM.peer ...
Sant Fournier, Mary Ann, The Synapse
core  

Quantitative Analysis Linking Inner Hair Cell Voltage Changes and Postsynaptic Conductance Change: A Modelling Study [PDF]

open access: yes, 2015
This paper presents a computational model which estimates the postsynaptic conductance change of mammalian Type I afferent peripheral process when airborne acoustic waves impact on the tympanic membrane. A model of the human auditory periphery is used to
Drakakis, EM, Prokopiou, AN
core   +3 more sources

The Versatile Synapse [PDF]

open access: yesJournal of Experimental Biology, 1984
ABSTRACT‘Typically’ chemical synaptic transmission takes place when an influx of calcium ions during a presynaptic nerve impulse triggers exocytosis of neurotransmitter substance from synaptic vesicles. The neurotransmitter diffuses across the synaptic cleft and occupies receptors embedded in the subsynaptic membrane.
openaire   +2 more sources

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

open access: yesFEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado   +4 more
wiley   +1 more source

Synapse: Synthetic Application Profiler and Emulator

open access: yes, 2016
We introduce Synapse motivated by the needs to estimate and emulate workload execution characteristics on high-performance and distributed heterogeneous resources.
Jha, Shantenu, Merzky, Andre
core   +1 more source

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