Results 141 to 150 of about 352,422 (329)
Fine Structural Localization of Acetylcholinesterase at a Cholinergic Vasodilator Nerve-Arterial Smooth Muscle Synapse [PDF]
, 1969 Christopher Bell
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Flexible Sensor‐Based Human–Machine Interfaces with AI Integration for Medical Robotics
Advanced Robotics Research, EarlyView.This review explores how flexible sensing technology and artificial intelligence (AI) significantly enhance human–machine interfaces in medical robotics. It highlights key sensing mechanisms, AI‐driven advancements, and applications in prosthetics, exoskeletons, and surgical robotics.
Yuxiao Wang +5 more
wiley +1 more source
Advanced Science, EarlyView.Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu +7 more
wiley +1 more source
The structures of the glia and of the synapses in the sympathetic chain of man [PDF]
, 1960 Katja Scharenberg
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NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea
Advanced Science, EarlyView.This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi +16 more
wiley +1 more source
THE FINE STRUCTURE OF INHIBITORY SYNAPSES IN THE CRAYFISH [PDF]
, 1961 R. Price Peterson, Frank A. Pepe
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Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD
Advanced Science, EarlyView.TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang +9 more
wiley +1 more source
Heterointerface‐Modulated Synthetic Synapses Exhibiting Complex Multiscale Plasticity
Advanced Science, EarlyView.An asymmetric dual‐gate heterointerface‐regulated artificial synapse (HRAS) is developed, employing distinct ion concentrations and dielectric coupling to form precise dual‐interface channels. Through lateral modulation, HRAS realizes, for the first time, the intricate interplay of lateral inhibition/enhancement and multi‐level short‐ and long‐term ...
Xingji Liu +14 more
wiley +1 more source