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Organic Synapses for Neuromorphic Electronics: From Brain-Inspired Computing to Sensorimotor Nervetronics.

Accounts of Chemical Research, 2019
Living organisms have a long evolutionary history that has provided them with functions and structures that enable them to survive in their environment. The goal of biomimetic technology is to emulate these traits of living things.
Yeongjun Lee, Tae‐Woo Lee
semanticscholar   +1 more source

Artificial Synapses Based on Multiterminal Memtransistors for Neuromorphic Application

Advanced Functional Materials, 2019
Neuromorphic computing, which emulates the biological neural systems could overcome the high‐power consumption issue of conventional von‐Neumann computing. State‐of‐the‐art artificial synapses made of two‐terminal memristors, however, show variability in
Lin Wang   +17 more
semanticscholar   +1 more source

Electrical synapses and their functional interactions with chemical synapses [PDF]

open access: yesNature Reviews Neuroscience, 2014
Brain function relies on the ability of neurons to communicate with each other. Interneuronal communication primarily takes place at synapses, where information from one neuron is rapidly conveyed to a second neuron. There are two main modalities of synaptic transmission: chemical and electrical. Far from functioning independently and serving unrelated
Alberto E Pereda
exaly   +3 more sources

Mitochondria at the Synapse

The Neuroscientist, 2006
Synapses are packed with mitochondria, complex organelles with roles in energy metabolism, cell signaling, and calcium homeostasis. However, the precise mechanisms by which mitochondria influence neurotrans mission remain undefined. In this review, the authors discuss pharmacological and genetic analyses of synaptic mitochondrial function, focusing on
Cindy V, Ly, Patrik, Verstreken
openaire   +2 more sources

THALAMOCORTICAL SYNAPSES

Progress in Neurobiology, 1997
Thalamocortical synapses inform the cerebral neocortex about the external and internal worlds. The thalamus produces myriad thalamocortical pathways that vary in morphological, physiological, pharmacological and functional properties. All these features are of great importance for understanding how information is acquired, integrated, processed, stored
M A, Castro-Alamancos, B W, Connors
openaire   +2 more sources

Memristive Synapses and Neurons for Bioinspired Computing

Advanced Electronic Materials, 2019
To realize highly efficient neuromorphic computing that is comparable to biological counterparts, bioinspired computing systems, consisting of biorealistic artificial synapses and neurons, are developed with memristive devices with native dynamics ...
Rui Yang, He-Ming Huang, Xin Guo
semanticscholar   +1 more source

Ubiquitin and the synapse

Nature Reviews Neuroscience, 2002
Post-translational modification by the attachment of ubiquitin seems to have a crucial role in regulating synaptic structure and function. By controlling the stability, activity and localization of target proteins, this versatile regulatory system can shape the pattern, activity and plasticity of synaptic connections.
Ashok N, Hegde, Aaron, DiAntonio
openaire   +2 more sources

The synapse in schizophrenia

European Journal of Neuroscience, 2014
AbstractIt has been several decades since synaptic dysfunction was first suggested to play a role in schizophrenia, but only in the last few years has convincing evidence been obtained as progress has been made in elucidating the genetic underpinnings of the disorder.
Andrew J, Pocklington   +2 more
openaire   +2 more sources

PDZ domain proteins of synapses

Nature Reviews Neuroscience, 2004
Eunjoon Kim, Morgan Sheng
exaly   +2 more sources

The immunological synapse

Molecular Immunology, 2002
The immunological synapse plays a central role in organising the immune system. Through their synaptic activity both T and B cells usually, but not always, acquire the information that critically determines the level and nature of the responses that they make. For T cells much of that information comes from epicrine and paracrine cell-cell interactions
R J, Creusot   +2 more
openaire   +2 more sources

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