Results 31 to 40 of about 454,876 (378)

Connexin36 Expression in the Mammalian Retina: A Multiple-Species Comparison

open access: yesFrontiers in Cellular Neuroscience, 2017
Much knowledge about interconnection of human retinal neurons is inferred from results on animal models. Likewise, there is a lack of information on human retinal electrical synapses/gap junctions (GJ).
Tamás Kovács-Öller   +25 more
doaj   +1 more source

Face classification using electronic synapses

open access: yesNature Communications, 2017
Conventional hardware platforms consume huge amount of energy for cognitive learning due to the data movement between the processor and the off-chip memory.
P. Yao   +10 more
semanticscholar   +1 more source

Super-resolution imaging and estimation of protein copy numbers at single synapses with DNA-PAINT [PDF]

open access: yes, 2019
In the brain, the strength of each individual synapse is defined by the complement of proteins present or the "local proteome." Activity-dependent changes in synaptic strength are the result of changes in this local proteome and posttranslational protein
Böger, C.   +8 more
core   +2 more sources

Alpha Waves as a Neuromarker of Autism Spectrum Disorder: The Challenge of Reproducibility and Heterogeneity

open access: yesFrontiers in Neuroscience, 2018
Background: There is no consensus in the literature concerning the presence of abnormal alpha wave profiles in patients with autism spectrum disorder (ASD).
Aline Lefebvre   +26 more
doaj   +1 more source

Associative memory neurons of encoding multi-modal signals are recruited by neuroligin-3-mediated new synapse formation

open access: yeseLife, 2023
The joint storage and reciprocal retrieval of learnt associated signals are presumably encoded by associative memory cells. In the accumulation and enrichment of memory contents in lifespan, a signal often becomes a core signal associatively shared for ...
Yang Xu   +4 more
doaj   +1 more source

Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction

open access: yesNature Communications, 2017
Microglia are highly motile glial cells that are proposed to mediate synaptic pruning during neuronal circuit formation. Disruption of signaling between microglia and neurons leads to an excess of immature synaptic connections, thought to be the result ...
L. Weinhard   +11 more
semanticscholar   +1 more source

Structural basis of astrocytic Ca2+ signals at tripartite synapses

open access: yesNature Communications, 2020
Astrocytic Ca2+ signals can be fast and local, supporting the idea that astrocytes have the ability to regulate single synapses. However, the anatomical basis of such specific signaling remains unclear, owing to difficulties in resolving the spongiform ...
Misa Arizono   +13 more
semanticscholar   +1 more source

Autophagy at the synapse [PDF]

open access: yesNeuroscience Letters, 2019
As the sites of communication between neurons, synapses depend upon precisely regulated protein-protein interactions to support neurotransmitter release and reception. Moreover, neuronal synapses typically exist great distances (i.e. up to meters) away from cell bodies, which are the sources of new proteins and the major sites of protein degradation ...
Clarissa L. Waites   +2 more
openaire   +3 more sources

Intracellular Trafficking Mechanisms of Synaptic Dysfunction in Alzheimer’s Disease

open access: yesFrontiers in Cellular Neuroscience, 2020
Alzheimer’s disease (AD) is the most common neurodegenerative disease characterized by progressive memory loss. Although AD neuropathological hallmarks are extracellular amyloid plaques and intracellular tau tangles, the best correlate of disease ...
Catarina Perdigão   +5 more
doaj   +1 more source

Microglia Depletion-Induced Remodeling of Extracellular Matrix and Excitatory Synapses in the Hippocampus of Adult Mice

open access: yesCells, 2021
The extracellular matrix (ECM) plays a key role in synaptogenesis and the regulation of synaptic functions in the central nervous system. Recent studies revealed that in addition to dopaminergic and serotoninergic neuromodulatory systems, microglia also ...
Luisa Strackeljan   +6 more
doaj   +1 more source

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