Results 31 to 40 of about 460,902 (390)
Structural basis of astrocytic Ca2+ signals at tripartite synapses
Nature Communications, 2020 Astrocytic Ca2+ signals can be fast and local, supporting the idea that astrocytes have the ability to regulate single synapses. However, the anatomical basis of such specific signaling remains unclear, owing to difficulties in resolving the spongiform ...
Misa Arizono +13 more
semanticscholar +1 more source
Autophagy at the synapse [PDF]
Neuroscience Letters, 2019 As the sites of communication between neurons, synapses depend upon precisely regulated protein-protein interactions to support neurotransmitter release and reception. Moreover, neuronal synapses typically exist great distances (i.e. up to meters) away from cell bodies, which are the sources of new proteins and the major sites of protein degradation ...
Clarissa L. Waites +2 more
openaire +3 more sources
Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction
Nature Communications, 2017 Microglia are highly motile glial cells that are proposed to mediate synaptic pruning during neuronal circuit formation. Disruption of signaling between microglia and neurons leads to an excess of immature synaptic connections, thought to be the result ...
L. Weinhard +11 more
semanticscholar +1 more source
Recent Progress in Photonic Synapses for Neuromorphic Systems
Advanced Intelligent Systems, 2020 Implementing synaptic functions with electronic devices is critical to achieve neuromorphic systems on the hardware platform, as synapses play important roles in brain computing and memory.
Junyao Zhang +4 more
semanticscholar +1 more source
Spatial representation of temporal information through spike timing dependent plasticity [PDF]
, 2003 We suggest a mechanism based on spike time dependent plasticity (STDP) of synapses to store, retrieve and predict temporal sequences. The mechanism is demonstrated in a model system of simplified integrate-and-fire type neurons densely connected by STDP ...
A. Herz +45 more
core +3 more sources
SynEM, automated synapse detection for connectomics
eLife, 2017 Nerve tissue contains a high density of chemical synapses, about 1 per µm3 in the mammalian cerebral cortex. Thus, even for small blocks of nerve tissue, dense connectomic mapping requires the identification of millions to billions of synapses. While the
Benedikt Staffler +5 more
doaj +1 more source
The role of peptidyl-prolyl isomerase Pin1 in neuronal signaling in epilepsy
Frontiers in Molecular Neuroscience, 2022 Epilepsy is a common symptom of many neurological disorders and can lead to neuronal damage that plays a major role in seizure-related disability.
Yuwen Chen +10 more
doaj +1 more source
Drosophila gustatory projections are segregated by taste modality and connectivity
eLife, 2022 Gustatory sensory neurons detect caloric and harmful compounds in potential food and convey this information to the brain to inform feeding decisions. To examine the signals that gustatory neurons transmit and receive, we reconstructed gustatory axons ...
Stefanie Engert +3 more
doaj +1 more source
eLife, 2016 Synaptic vesicles in rodent neurons are recycled using at least two distinct mechanisms.
Henrique von Gersdorff, Owen P Gross
openaire +4 more sources
A population of immature cerebellar parallel fibre synapses are insensitive to adenosine but are inhibited by hypoxia [PDF]
, 2011 The purine adenosine plays an important role in a number of physiological and pathological processes and is neuroprotective during hypoxia and ischemia.
Atterbury, Alison, Wall, Mark J.
core +1 more source