Results 31 to 40 of about 471,836 (383)

SynEM, automated synapse detection for connectomics

open access: yeseLife, 2017
Nerve tissue contains a high density of chemical synapses, about 1 per µm3 in the mammalian cerebral cortex. Thus, even for small blocks of nerve tissue, dense connectomic mapping requires the identification of millions to billions of synapses. While the
Benedikt Staffler   +5 more
doaj   +1 more source

The role of peptidyl-prolyl isomerase Pin1 in neuronal signaling in epilepsy

open access: yesFrontiers in Molecular Neuroscience, 2022
Epilepsy is a common symptom of many neurological disorders and can lead to neuronal damage that plays a major role in seizure-related disability.
Yuwen Chen   +10 more
doaj   +1 more source

Homogeneous Spiking Neuromorphic System for Real-World Pattern Recognition [PDF]

open access: yes, 2015
A neuromorphic chip that combines CMOS analog spiking neurons and memristive synapses offers a promising solution to brain-inspired computing, as it can provide massive neural network parallelism and density.
Saxena, Vishal, Wu, Xinyu, Zhu, Kehan
core   +3 more sources

Recent Progress in Photonic Synapses for Neuromorphic Systems

open access: yesAdvanced Intelligent Systems, 2020
Implementing synaptic functions with electronic devices is critical to achieve neuromorphic systems on the hardware platform, as synapses play important roles in brain computing and memory.
Junyao Zhang   +4 more
semanticscholar   +1 more source

Drosophila gustatory projections are segregated by taste modality and connectivity

open access: yeseLife, 2022
Gustatory sensory neurons detect caloric and harmful compounds in potential food and convey this information to the brain to inform feeding decisions. To examine the signals that gustatory neurons transmit and receive, we reconstructed gustatory axons ...
Stefanie Engert   +3 more
doaj   +1 more source

A population of immature cerebellar parallel fibre synapses are insensitive to adenosine but are inhibited by hypoxia [PDF]

open access: yes, 2011
The purine adenosine plays an important role in a number of physiological and pathological processes and is neuroprotective during hypoxia and ischemia.
Atterbury, Alison, Wall, Mark J.
core   +1 more source

Neuromuscular synapse [PDF]

open access: yesBiochemistry and Molecular Biology Education, 2009
AbstractDiverse biological data may be used to create illustrations of molecules in their cellular context. I describe the scientific results that support a recent textbook illustration of the neuromuscular synapse. The image magnifies a portion of the synapse at one million times, showing the location and the form of individual macromolecules. Results
openaire   +2 more sources

Targeted complement inhibition at synapses prevents microglial synaptic engulfment and synapse loss in demyelinating disease

open access: yesbioRxiv, 2019
Multiple sclerosis (MS) is a demyelinating, autoimmune disease of the central nervous system. While work has focused on axon loss in MS, far less is known about synaptic changes.
Sebastian Werneburg   +10 more
semanticscholar   +1 more source

Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4. [PDF]

open access: yes, 2014
Lrp4, the muscle receptor for neuronal Agrin, is expressed in the hippocampus and areas involved in cognition. The function of Lrp4 in the brain, however, is unknown, as Lrp4-/- mice fail to form neuromuscular synapses and die at birth.
Burden, Steven J   +2 more
core   +1 more source

Noise-modulated multistable synapses in a Wilson-Cowan-based model of plasticity

open access: yesFrontiers in Computational Neuroscience, 2023
Frequency-dependent plasticity refers to changes in synaptic strength in response to different stimulation frequencies. Resonance is a factor known to be of importance in such frequency dependence, however, the role of neural noise in the process remains
Caroline A. Lea-Carnall   +2 more
doaj   +1 more source

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