Results 41 to 50 of about 466,973 (293)
bioRxiv, 2019 Multiple sclerosis (MS) is a demyelinating, autoimmune disease of the central nervous system. While work has focused on axon loss in MS, far less is known about synaptic changes.
Sebastian Werneburg +10 more
semanticscholar +1 more source
Learning through ferroelectric domain dynamics in solid-state synapses
Nature Communications, 2017 In the brain, learning is achieved through the ability of synapses to reconfigure the strength by which they connect neurons (synaptic plasticity). In promising solid-state synapses called memristors, conductance can be finely tuned by voltage pulses and
S. Boyn +15 more
semanticscholar +1 more source
Noise-modulated multistable synapses in a Wilson-Cowan-based model of plasticity
Frontiers in Computational Neuroscience, 2023 Frequency-dependent plasticity refers to changes in synaptic strength in response to different stimulation frequencies. Resonance is a factor known to be of importance in such frequency dependence, however, the role of neural noise in the process remains
Caroline A. Lea-Carnall +2 more
doaj +1 more source
Why Neurons Have Thousands of Synapses, A Theory of Sequence Memory in Neocortex [PDF]
, 2015 Neocortical neurons have thousands of excitatory synapses. It is a mystery how neurons integrate the input from so many synapses and what kind of large-scale network behavior this enables.
Ahmad, Subutai, Hawkins, Jeff
core +3 more sources
Is plasticity of synapses the mechanism of long-term memory storage?
npj Science of Learning, 2019 It has been 70 years since Donald Hebb published his formalized theory of synaptic adaptation during learning. Hebb’s seminal work foreshadowed some of the great neuroscientific discoveries of the following decades, including the discovery of long-term ...
W. Abraham, O. Jones, D. Glanzman
semanticscholar +1 more source
Biology, 2015 A key event in Alzheimer’s disease (AD) is the production of amyloid-β (Aβ) peptides and the loss of synapses. In cultured neurons Aβ triggered synapse damage as measured by the loss of synaptic proteins. α-synuclein (αSN), aggregates of which accumulate
Clive Bate, Alun Williams
doaj +1 more source
eLife, 2023 The joint storage and reciprocal retrieval of learnt associated signals are presumably encoded by associative memory cells. In the accumulation and enrichment of memory contents in lifespan, a signal often becomes a core signal associatively shared for ...
Yang Xu +4 more
doaj +1 more source
Ectopic localization of neural crest cells: etiological factor of scoliosis
Хирургия позвоночника, 2015 Objective. To identify cell phenotypes in vertebral body growth plates from patients with idiopathic scoliosis. Material and Methods. Cells were isolated from vertebral body growth plates both on convex and concave sides of the de- formity in 50 ...
Alla M. Zaidman +6 more
doaj +1 more source
Storage Capacity of Extremely Diluted Hopfield Model
, 2004 The storage capacity of the extremely diluted Hopfield Model is studied by using Monte Carlo techniques. In this work, instead of diluting the synapses according to a given distribution, the dilution of the synapses is obtained systematically by ...
BURCU AKCAN +2 more
core +1 more source
Protein synthesis at synaptic sites on dendrites [PDF]
, 2001 Studies over the past 20 years have revealed that gene expression in neurons is carried out by a distributed network of translational machinery. One component of this network is localized in dendrites, where polyribosomes and associated membranous ...
Schuman, Erin M., Steward, Oswald
core +1 more source