Results 41 to 50 of about 460,902 (390)

Targeted complement inhibition at synapses prevents microglial synaptic engulfment and synapse loss in demyelinating disease

open access: yesbioRxiv, 2019
Multiple sclerosis (MS) is a demyelinating, autoimmune disease of the central nervous system. While work has focused on axon loss in MS, far less is known about synaptic changes.
Sebastian Werneburg   +10 more
semanticscholar   +1 more source

Learning through ferroelectric domain dynamics in solid-state synapses

open access: yesNature Communications, 2017
In the brain, learning is achieved through the ability of synapses to reconfigure the strength by which they connect neurons (synaptic plasticity). In promising solid-state synapses called memristors, conductance can be finely tuned by voltage pulses and
S. Boyn   +15 more
semanticscholar   +1 more source

The Immunological Synapse

open access: yesAnnual Review of Immunology, 2001
The adaptive immune response is initiated by the interaction of T cell antigen receptors with major histocompatibility complex molecule-peptide complexes in the nanometer scale gap between a T cell and an antigen-presenting cell, referred to as an immunological synapse.
Bromley, S   +9 more
openaire   +4 more sources

Homogeneous Spiking Neuromorphic System for Real-World Pattern Recognition [PDF]

open access: yes, 2015
A neuromorphic chip that combines CMOS analog spiking neurons and memristive synapses offers a promising solution to brain-inspired computing, as it can provide massive neural network parallelism and density.
Saxena, Vishal, Wu, Xinyu, Zhu, Kehan
core   +3 more sources

Noise-modulated multistable synapses in a Wilson-Cowan-based model of plasticity

open access: yesFrontiers in Computational Neuroscience, 2023
Frequency-dependent plasticity refers to changes in synaptic strength in response to different stimulation frequencies. Resonance is a factor known to be of importance in such frequency dependence, however, the role of neural noise in the process remains
Caroline A. Lea-Carnall   +2 more
doaj   +1 more source

Is plasticity of synapses the mechanism of long-term memory storage?

open access: yesnpj Science of Learning, 2019
It has been 70 years since Donald Hebb published his formalized theory of synaptic adaptation during learning. Hebb’s seminal work foreshadowed some of the great neuroscientific discoveries of the following decades, including the discovery of long-term ...
W. Abraham, O. Jones, D. Glanzman
semanticscholar   +1 more source

RNA and the synapse [PDF]

open access: yesRNA, 2015
One reason we learn and remember is because synapses, the places where axons and dendrites meet, undergo experience-dependent changes whose long-lasting nature may underlie the formation and persistence of memory. Indeed, neurons use these morphological and biochemical alterations to distinguish experienced (i.e., stimulated) from naive (unstimulated ...
openaire   +3 more sources

Identifiability of a Binomial Synapse [PDF]

open access: yesFrontiers in Computational Neuroscience, 2020
Frontiers in Computational Neuroscience ...
Camille Gontier   +2 more
openaire   +5 more sources

Why Neurons Have Thousands of Synapses, A Theory of Sequence Memory in Neocortex [PDF]

open access: yes, 2015
Neocortical neurons have thousands of excitatory synapses. It is a mystery how neurons integrate the input from so many synapses and what kind of large-scale network behavior this enables.
Ahmad, Subutai, Hawkins, Jeff
core   +3 more sources

Synaptic actions of amyotrophic-lateral-sclerosis-associated G85R-SOD1 in the squid giant synapse [PDF]

open access: yes, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Song, Y.
Song, Yuyu
core   +1 more source

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