Results 41 to 50 of about 471,836 (383)
Why Neurons Have Thousands of Synapses, A Theory of Sequence Memory in Neocortex [PDF]
, 2015 Neocortical neurons have thousands of excitatory synapses. It is a mystery how neurons integrate the input from so many synapses and what kind of large-scale network behavior this enables.
Ahmad, Subutai, Hawkins, Jeff
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Is plasticity of synapses the mechanism of long-term memory storage?
npj Science of Learning, 2019 It has been 70 years since Donald Hebb published his formalized theory of synaptic adaptation during learning. Hebb’s seminal work foreshadowed some of the great neuroscientific discoveries of the following decades, including the discovery of long-term ...
W. Abraham, O. Jones, D. Glanzman
semanticscholar +1 more source
A brainwide atlas of synapses across the mouse life span
Science, 2020 Brain synapses through the life span Excitatory synapses connect neurons in the brain to build the circuits that enable behavior. Cizeron et al. surveyed synapses in the mouse brain from birth to old age and present the data as a community resource, the ...
Mélissa Cizeron +6 more
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Biology, 2015 A key event in Alzheimer’s disease (AD) is the production of amyloid-β (Aβ) peptides and the loss of synapses. In cultured neurons Aβ triggered synapse damage as measured by the loss of synaptic proteins. α-synuclein (αSN), aggregates of which accumulate
Clive Bate, Alun Williams
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eLife, 2023 The joint storage and reciprocal retrieval of learnt associated signals are presumably encoded by associative memory cells. In the accumulation and enrichment of memory contents in lifespan, a signal often becomes a core signal associatively shared for ...
Yang Xu +4 more
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Storage Capacity of Extremely Diluted Hopfield Model
, 2004 The storage capacity of the extremely diluted Hopfield Model is studied by using Monte Carlo techniques. In this work, instead of diluting the synapses according to a given distribution, the dilution of the synapses is obtained systematically by ...
BURCU AKCAN +2 more
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Ectopic localization of neural crest cells: etiological factor of scoliosis
Хирургия позвоночника, 2015 Objective. To identify cell phenotypes in vertebral body growth plates from patients with idiopathic scoliosis. Material and Methods. Cells were isolated from vertebral body growth plates both on convex and concave sides of the de- formity in 50 ...
Alla M. Zaidman +6 more
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Dystonia: sparse synapses for D2 receptors in striatum of a DYT1 knock-out mouse model [PDF]
, 2020 Dystonia pathophysiology has been partly linked to downregulation and dysfunction of dopamine D2 receptors in striatum. We aimed to investigate the possible morpho-structural correlates of D2 receptor downregulation in the striatum of a DYT1 Tor1a mouse ...
Biagioni, S. +8 more
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iScienceSummary: Retinal ganglion cells (RGCs) summate inputs and forward a spike train code to the brain in the form of either maintained spiking (sustained) or a quickly decaying brief spike burst (transient).
Gergely Szarka +8 more
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Heterosynaptic Plasticity and the Experience-Dependent Refinement of Developing Neuronal Circuits
Frontiers in Neural Circuits, 2021 Neurons remodel the structure and strength of their synapses during critical periods of development in order to optimize both perception and cognition.
Kyle R. Jenks +4 more
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