Results 21 to 30 of about 26,734 (323)

DNA double-strand break end synapsis by DNA loop extrusion

open access: yesbioRxiv, 2021
DNA double-strand breaks (DSBs) occur every cell cycle and must be efficiently repaired. Non-homologous end joining (NHEJ) is the dominant pathway for DSB repair in G1-phase.
Jin Yang, Hugo B. Brandão, A. Hansen
semanticscholar   +1 more source

Evidence that masking of synapsis imperfections counterbalances quality control to promote efficient meiosis. [PDF]

open access: yesPLoS Genetics, 2013
Reduction in ploidy to generate haploid gametes during sexual reproduction is accomplished by the specialized cell division program of meiosis. Pairing between homologous chromosomes and assembly of the synaptonemal complex at their interface (synapsis ...
Susanna Mlynarczyk-Evans   +2 more
doaj   +1 more source

Heat stress interferes with formation of double-strand breaks and homolog synapsis.

open access: yesPlant Physiology, 2021
Meiotic recombination (MR) drives novel combinations of alleles and contributes to genomic diversity in eukaryotes. In this study, we showed that heat stress (36°C-38°C) over the fertile threshold fully abolished crossover formation in Arabidopsis ...
Yingjie Ning   +11 more
semanticscholar   +1 more source

A Compact Fully Electronically Tunable Memristive Circuit Based on CCCDTA with Experimental Results

open access: yesMicromachines, 2023
This work presents a flux-controlled memristor structure employing a Current-Controlled Current Differencing Transconductance Amplifier (CCCDTA) with a grounded capacitor.
Deniz Ozenli
doaj   +1 more source

ASYNAPSIS 1 ensures crossover fidelity in polyploid wheat by promoting homologous recombination and suppressing non-homologous recombination

open access: yesFrontiers in Plant Science, 2023
During meiosis, the chromosome axes and synaptonemal complex mediate chromosome pairing and homologous recombination to maintain genomic stability and accurate chromosome segregation.
Chiara Di Dio   +3 more
doaj   +1 more source

Privación sensorial temprana durante el neurodesarrollo y sus consecuencias cognitivas

open access: yesMedicina U.P.B., 2020
La aparición progresiva de habilidades sensoriales, motoras y cognitivo-afectivas en el humano a lo largo de su desarrollo es un reflejo de cambios fisiológicos que se gestan al interior del sistema nervioso.
Juan Felipe Álvarez Restrepo   +1 more
doaj   +1 more source

The Absence of Caspase-8 in the Dopaminergic System Leads to Mild Autism-like Behavior

open access: yesFrontiers in Cell and Developmental Biology, 2022
In the last decade, new non-apoptotic roles have been ascribed to apoptotic caspases. This family of proteins plays an important role in the sculpting of the brain in the early stages of development by eliminating excessive and nonfunctional synapses and
I. Suárez-Pereira   +15 more
doaj   +1 more source

Meiotic Chromosome Stability and Suppression of Crossover Between Non-homologous Chromosomes in xBrassicoraphanus, an Intergeneric Allotetraploid Derived From a Cross Between Brassica rapa and Raphanus sativus

open access: yesFrontiers in Plant Science, 2020
Hybridization and polyploidization are major driving forces in plant evolution. Allopolyploids can be occasionally formed from a cross between distantly related species but often suffer from chromosome instability and infertility. xBrassicoraphanus is an
Hye Rang Park   +15 more
doaj   +1 more source

Regulation of microglia phagocytosis and potential involvement of exercise

open access: yesFrontiers in Cellular Neuroscience, 2022
Microglia are considered the main phagocytic cells in the central nervous system, remodeling neural circuits by pruning synapses during development. Microglial phagocytosis is also a crucial process in maintaining adult brain homeostasis and clearing ...
Congqin Li   +10 more
doaj   +1 more source

The novel synaptonemal complex central element SCEP3 interlinks synapsis initiation and crossover formation in Arabidopsis thaliana [PDF]

open access: gold
Heckmann S   +10 more
europepmc   +2 more sources

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