Results 21 to 30 of about 10,129 (257)
Dynamics of rye chromosome 1R regions with high or low crossover frequency in homology search and synapsis development. [PDF]
In many organisms, homologous pairing and synapsis depend on the meiotic recombination machinery that repairs double-strand DNA breaks (DSBs) produced at the onset of meiosis.
Nohelia T Valenzuela +2 more
doaj +1 more source
Crossover interference mechanism: New lessons from plants
Plants are the source of our understanding of several fundamental biological principles. It is well known that Gregor Mendel discovered the laws of Genetics in peas and that maize was used for the discovery of transposons by Barbara McClintock.
Nahid Rafiei, Arnaud Ronceret
doaj +1 more source
Cylindrospermopsin (CYN) is a cyanotoxin whose incidence has been increasing in the last decades. Due to its capacity to exert damage at different levels of the organism, it is considered a cytotoxin.
María G. Hinojosa +6 more
doaj +1 more source
Chromosome Organization in Early Meiotic Prophase
One of the most fascinating aspects of meiosis is the extensive reorganization of the genome at the prophase of the first meiotic division (prophase I). The first steps of this reorganization are observed with the establishment of an axis structure, that
Corinne Grey, Bernard de Massy
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Phospho-Regulation of Meiotic Prophase
Germ cells undergoing meiosis rely on an intricate network of surveillance mechanisms that govern the production of euploid gametes for successful sexual reproduction.
Funda M. Kar, Andreas Hochwagen
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Centromere Clustering: Where Synapsis Begins [PDF]
Centromeres congregate into a large cluster called the chromocenter during Drosophila oogenesis. Two recent studies now define a function and a genetic basis for this remarkable structure.
Subramanian, Vijayalakshmi V. +1 more
openaire +3 more sources
Tau oligomers: the toxic player at synapses in Alzheimer’s disease
Alzheimer’s disease (AD) is a progressive disorder in which the most noticeable symptoms are cognitive impairment and memory loss. However, the precise mechanism by which those symptoms develop remains unknown.
Marcos Jair Guerrero-Munoz +2 more
doaj +1 more source
Meiosis involves a series of specific chromosome events, namely homologous synapsis, recombination, and segregation. Disruption of either recombination or synapsis in mammals results in the interruption of meiosis progression during the first meiotic ...
Roberto de la Fuente +10 more
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The production of balanced fertile haploid gametes requires the faithful separation of paired (synapsed) chromosomes toward the end of meiotic prophase I (desynapsis).
Isabelle Colas +9 more
doaj +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source

