Results 21 to 30 of about 1,301 (201)
Crossover interference mechanism: New lessons from plants
Frontiers in Cell and Developmental Biology, 2023 Plants are the source of our understanding of several fundamental biological principles. It is well known that Gregor Mendel discovered the laws of Genetics in peas and that maize was used for the discovery of transposons by Barbara McClintock.
Nahid Rafiei, Arnaud Ronceret
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Meiotic cohesin SMC1β provides prophase I centromeric cohesion and is required for multiple synapsis-associated functions. [PDF]
PLoS Genetics, 2013 Cohesin subunit SMC1β is specific and essential for meiosis. Previous studies showed functions of SMC1β in determining the axis-loop structure of synaptonemal complexes (SCs), in providing sister chromatid cohesion (SCC) in metaphase I and thereafter, in
Uddipta Biswas +6 more
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Phospho-Regulation of Meiotic Prophase
Frontiers in Cell and Developmental Biology, 2021 Germ cells undergoing meiosis rely on an intricate network of surveillance mechanisms that govern the production of euploid gametes for successful sexual reproduction.
Funda M. Kar, Andreas Hochwagen
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Chromosome Organization in Early Meiotic Prophase
Frontiers in Cell and Developmental Biology, 2021 One of the most fascinating aspects of meiosis is the extensive reorganization of the genome at the prophase of the first meiotic division (prophase I). The first steps of this reorganization are observed with the establishment of an axis structure, that
Corinne Grey, Bernard de Massy
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Meiotic behavior of small chromosomes in maize
Frontiers in Plant Science, 2013 The typical behavior of chromosomes in meiosis is that homologous pairs synapse, recombine and then separate at anaphase I. At anaphase II, sister chromatids separate.
James A. Birchler, Fangpu eHan
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Toxins, 2022 Cylindrospermopsin (CYN) is a cyanotoxin whose incidence has been increasing in the last decades. Due to its capacity to exert damage at different levels of the organism, it is considered a cytotoxin.
María G. Hinojosa +6 more
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Contribution of Tau Pathology to Mitochondrial Impairment in Neurodegeneration
Frontiers in Neuroscience, 2018 Tau is an essential protein that physiologically promotes the assembly and stabilization of microtubules, and participates in neuronal development, axonal transport, and neuronal polarity.
María J. Pérez +5 more
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Frontiers in Plant Science, 2017 The production of balanced fertile haploid gametes requires the faithful separation of paired (synapsed) chromosomes toward the end of meiotic prophase I (desynapsis).
Isabelle Colas +9 more
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PLoS Genetics, 2012 Chromosomes that fail to synapse during meiosis become enriched for chromatin marks associated with heterochromatin assembly. This response, called meiotic silencing of unsynapsed or unpaired chromatin (MSUC), is conserved from fungi to mammals.
Piero Lamelza, Needhi Bhalla
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Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations
FEBS Open Bio, EarlyView.We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo +2 more
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