Results 111 to 120 of about 571,868 (347)

Protocol for detecting palmitoylation of high-molecular-weight rat synaptic proteins via acyl-PEG labeling

STAR Protocols
Summary: Here, we present an optimized acyl-PEGyl exchange gel shift (APEGS) assay to monitor palmitoylation of high-molecular-weight proteins from primary neuronal cultures.
Busra Perihan Yucel, Jeremy Martin Henley, Kevin Anthony Wilkinson   +2 more
doaj   +1 more source

PKCα integrates spatiotemporally distinct Ca2+ and autocrine BDNF signaling to facilitate synaptic plasticity

Nature Neuroscience, 2018
The protein kinase C (PKC) enzymes have long been established as critical for synaptic plasticity. However, it is unknown whether Ca2+-dependent PKC isozymes are activated in dendritic spines during plasticity and, if so, how this synaptic activity is ...
Lesley A. Colgan, Mo Hu, J. Misler, Paula Parra-Bueno, Corey Moran, M. Leitges, R. Yasuda   +6 more
semanticscholar   +1 more source

Role of Amorphous Phases in Mixed Conduction of Conjugated Regioblock Copolymers for Organic Electrochemical Synaptic Transistors

Advanced Materials, EarlyView.
Critical roles of amorphous and crystalline phases in polymer‐based mixed ionic‐electronic conductors for organic electrochemical synaptic transistors using conjugated regioregular‐block‐regiorandom copolymers are demonstrated. Amorphous phases contribute to gradual polaron formation and strong ion trapping by bipolarons, leading to improved synaptic ...
Kwang‐Hun Choi, Seongil Im, Aaron Plant, Carlos Neri Soto, Hanna Lee, Changsoon Choi, Ho Won Jang, Jeong Ho Cho, Hyunsu Ju, Youngmin Lee, Jung Ah Lim   +10 more
wiley   +1 more source

Routing Hippocampal Information Flow through Parvalbumin Interneuron Plasticity in Area CA2

Cell Reports, 2019
Summary: The hippocampus is critical for the formation of episodic memory. It is, therefore, important to understand intra-hippocampal circuitry, especially in the often overlooked area CA2.
Kaoutsar Nasrallah, Ludivine Therreau, Vincent Robert, Arthur J.Y. Huang, Thomas J. McHugh, Rebecca A. Piskorowski, Vivien Chevaleyre   +6 more
doaj   +1 more source

Ionic Conductive Textiles for Wearable Technology

Advanced Materials, EarlyView.
Recent advances in ionic conductive textiles for wearable technology are summarized, with a focus on soft ionic conductors that exhibit skin‐like flexibility and tissue‐like ion dynamics. Their structures, key characteristics, manufacturing methods, and diverse applications are reviewed.
Lingtao Fang, Yunlu Zhou, Qiyao Huang
wiley   +1 more source

Dopamine release regulation by astrocytes during cerebral ischemia

Neurobiology of Disease, 2013
Brain ischemia triggers excessive release of neurotransmitters that mediate neuronal damage following ischemic injury. The striatum is one of the areas most sensitive to ischemia.
Idaira Oliva, Miriam Fernández, Eduardo D. Martín   +2 more
doaj   +1 more source

Role of Immediate-Early Genes in Synaptic Plasticity and Neuronal Ensembles Underlying the Memory Trace

Frontiers in Molecular Neuroscience, 2016
In the brain, neuronal gene expression is dynamically changed in response to neuronal activity. In particular, the expression of immediate-early genes (IEGs) such as egr-1, c-fos, and Arc is rapidly and selectively upregulated in subsets of neurons in ...
Keiichiro Minatohara, M. Akiyoshi, H. Okuno   +2 more
semanticscholar   +1 more source

Brain‐Inspired In‐Memory Data Pruning and Computing with TaOx Mem‐Selectors

Advanced Materials, EarlyView.
In article number 2502168, Zhongrui Wang, Xiaoxin Xu, Dashan Shang, and co‐workers present the first nanoscale Mem‐Selector device that integrates both nonvolatile resistive memory and volatile threshold switching functionalities for visual data pruning.
Yi Li, Jinru Lai, Songqi Wang, Ning Lin, Xu Zheng, Wenxuan Sun, Danian Dong, Xiqing Xu, Haili Ma, Feng Zhang, Xiaojuan Qi, Zhongrui Wang, Xiaoxin Xu, Dashan Shang, Han Wang, Ming Liu   +15 more
wiley   +1 more source

Altered Short-Term Synaptic Plasticity in Mice Lacking the Metabotropic Glutamate Receptor mGlu7

The Scientific World Journal, 2002
Eight subtypes of metabotropic glutamate (mGlu) receptors have been identified of which two, mGlu5 and mGlu7, are highly expressed at synapses made between CA3 and CA1 pyramidal neurons in the hippocampus.
Trevor J. Bushell, Gilles Sansig, Valerie J. Collett, Herman van der Putten, Graham L. Collingridge   +4 more
doaj   +1 more source

Frequency Switching Neuristor for Realizing Intrinsic Plasticity and Enabling Robust Neuromorphic Computing

Advanced Materials, EarlyView.
A frequency switching (FS) neuristor is proposed, comprising a Mott memristor and a valence change mechanism (VCM) memristor. The FS neuristor exhibits a multi‐level frequency–voltage (f–V) characteristics, enabling the implementation of neuronal intrinsic plasticity transfer functions.
Woojoon Park, Hanchan Song, Eun Young Kim, Moon Gu Choi, Min Gu Lee, Hakseung Rhee, Gwangmin Kim, Taewook Go, Alba Martinez, Daehee Kim, Junmo Kang, Jae Hyun In, Kyung Min Kim   +12 more
wiley   +1 more source