Results 61 to 70 of about 1,092,184 (348)
Cell Calcium, 2005 The induction and maintenance of synaptic plasticity is well established to be a Ca2+-dependent process. The use of fluorescent imaging to monitor changes [Ca2+]i in neurones has revealed a diverse array of signaling patterns across the different compartments of the cell.
Cavazzini, M, Bliss, T, Emptage, N
openaire +4 more sources
eLife, 2021 The hippocampus is critical for memory formation. The hypothalamic supramammillary nucleus (SuM) sends long-range projections to hippocampal area CA2. While the SuM-CA2 connection is critical for social memory, how this input acts on the local circuit is
Vincent Robert +10 more
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Targeting homeostatic synaptic plasticity for treatment of mood disorders
Neuron, 2020 Ketamine exerts rapid antidepressant action in depressed and treatment resistant depressed patients within hours. At the same time, ketamine elicits a unique form of functional synaptic plasticity that shares several attributes and molecular mechanisms ...
E. Kavalali, L. Monteggia
semanticscholar +1 more source
Structural plasticity of synaptic connectivity in the adult hippocampal mossy fiber projection [PDF]
, 2013 The brain has the lifelong ability to change itself based on new experiences such as learning and memory. This so called neuronal plasticity is reflected in the brain by structural and functional modifications which underlie our ability to learn ...
Ruediger, Sarah
core +1 more source
Nature Communications, 2020 Inhibitory interneuron subtypes differentially control place cell representations in CA1. Here, the authors show that parvalbumin and somatostatin interneuron synapses onto CA1 pyramidal neurons exhibit distinct plasticity mechanisms and incorporating ...
Matt Udakis +4 more
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BDNF: A Key Factor with Multipotent Impact on Brain Signaling and Synaptic Plasticity
Cellular and molecular neurobiology, 2017 Brain-derived neurotrophic factor (BDNF) is one of the most widely distributed and extensively studied neurotrophins in the mammalian brain. Among its prominent functions, one can mention control of neuronal and glial development, neuroprotection, and ...
P. Kowiański +5 more
semanticscholar +1 more source
Glia as sculptors of synaptic plasticity
Neurosciences research, 2020 Glial cells are non-neuronal cells in the nervous system that are crucial for proper brain development and function. Three major classes of glia in the central nervous system (CNS) include astrocytes, microglia and oligodendrocytes.
L. Sancho, Minerva Contreras, N. Allen
semanticscholar +1 more source
Synaptic plasticity through activation of GluA3-containing AMPA-receptors
eLife, 2017 Excitatory synaptic transmission is mediated by AMPA-type glutamate receptors (AMPARs). In CA1 pyramidal neurons of the hippocampus two types of AMPARs predominate: those that contain subunits GluA1 and GluA2 (GluA1/2), and those that contain GluA2 and ...
Maria C Renner +7 more
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Linking spontaneous and stimulated spine dynamics
Communications Biology, 2023 Our brains continuously acquire and store memories through synaptic plasticity. However, spontaneous synaptic changes can also occur and pose a challenge for maintaining stable memories.
Maximilian F. Eggl +4 more
doaj +1 more source
Neurodegenerative Disease: What Potential Therapeutic Role of Acid-Sensing Ion Channels?
Frontiers in Cellular Neuroscience, 2021 Acidic pH shift occurs in many physiological neuronal activities such as synaptic transmission and synaptic plasticity but also represents a characteristic feature of many pathological conditions including inflammation and ischemia.
Dalila Mango +3 more
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