Results 141 to 150 of about 169,161 (276)

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

Advanced Science, EarlyView.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou, Sen Yang, Andrea Enriquez, Nino A. Espinas, Anoosha Sri, Caliel D. Hines, Jason M. Tennessen, Chia‐Shan Wu, Jui‐Yen Huang, Hui‐Chen Lu   +9 more
wiley   +1 more source

Neuron-specific WDR5 epigenetically upregulates ARID5B to impair GABAergic synaptic transmission and promotes epileptogenesis. [PDF]

Theranostics
Gu J, Ke PY, Zhang XY, Liu C, Yang Y, Yu ML, Xu ZZ, Zhang CX, Dong W.   +8 more
europepmc   +1 more source

A Review on Biodegradable Materials of Sustainable Soft Robotics and Electronics

Advanced Science, EarlyView.
Biodegradable materials are gaining increasing attention in soft robotics and electronics due to their environmental friendliness, showing great potential for sustainability. In this review, the classification of biodegradable materials, their applications in the field of soft robotics and electronics, as well as the challenges and future prospects ...
Yizhu Xie, Jiaxin Han, Xingyi Dai, Xuyang Zhang, Kangwen Xiao, Junhui Huang, Yajun Cao, Aihua Zhong, Long‐Biao Huang   +8 more
wiley   +1 more source

Correction: Utility of melatonin on brain injury, synaptic transmission, and energy metabolism in rats with sepsis. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Ates G, Tamer S, Ozkok E, Yorulmaz H, Gundogan GI, Aksu A, Balkis N.   +6 more
europepmc   +1 more source

CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human

Advanced Science, EarlyView.
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan, Jiafu Li, Min Shao, Haili Bao, Ajun Geng, Jialin Yang, Yu Tao, Xinyi Chen, Tianxiong Xiao, Chunye Liu, Zhiyao Xie, Wenqian Song, Qing Cissy Yu, Hongxing Fu, Xu Han, Taochen He, Wenquan Wang, Jianfeng Chen, Sheng Yan, Shaohua Song, Liang Liu, Yi Arial Zeng   +21 more
wiley   +1 more source

Regulated degradation of KCC2, a potassium-chloride co-transporter required for synaptic transmission and neurodevelopment. [PDF]

Channels (Austin)
Kok M, Aizenman E, Guerriero CJ, Brodsky JL.   +3 more
europepmc   +1 more source

Optimizing Synaptic Architecture and Efficiency for High-Frequency Transmission [PDF]

, 2002
Holger Taschenberger, Ricardo M. Leão, Kevin Rowland, George A. Spirou, Henrique von Gersdorff   +4 more
openalex   +1 more source

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

Synaptic Transmission [PDF]

Biophysical Journal, 2008
  +5 more sources

Synaptic transmission promotes brain metastatic outgrowth in breast cancer. [PDF]

JCI Insight
Mondal J, Nylund P, Malgulwar PB, Johnson WE, Huse JT.   +4 more
europepmc   +1 more source