Reading out a spatiotemporal population code by imaging neighbouring parallel fibre axons in vivo.
The spatiotemporal pattern of synaptic inputs to the dendritic tree is crucial for synaptic integration and plasticity. However, it is not known if input patterns driven by sensory stimuli are structured or random.
Wilms, CD, Häusser, M
core
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu +10 more
wiley +1 more source
Multiplexed changes in synaptic transmission underlie stress-induced reduction of persistent firing in the parietal cortex. [PDF]
Proddutur A +4 more
europepmc +1 more source
Chemical, Synaptic Transmission
v, 82 p.A knowledge of the means of transmission between neuronal units and the way in which nerves affect their effector organs is important to understanding the functioning of the nervous system.
Ditzler, John W., Jr.
core
CMOS‐Integrated Synaptic Photoreceptor Chip Inspired by Insect Visual Processing
CMOS‐integrated Si QDs/ReS2 synaptic photoreceptor array mimics the parallel processing and wavelength‐selective strategy of insect vision. By combining intrinsic ultraviolet‐violet sensitivity with synaptic plasticity, the chip enables frontend sensory redundancy reduction without external filters, offering a scalable pathway toward lowpower ...
Jian Chai +25 more
wiley +1 more source
Assessing the Potential of NGF-Differentiated PC12 Cells as a Model for Synaptic Transmission. [PDF]
Ott G +6 more
europepmc +1 more source
Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
A Narrative Review of Synaptic Transmission and Its Role in Neurological and Psychiatric Disorders: A Molecular Perspective. [PDF]
Ahmed N +5 more
europepmc +1 more source
Triple‐Mode Ferroelectric Thin‐Film Transistor for Hybrid Electrical–Optical Reservoir Computing
A triple‐mode ferroelectric thin‐film transistor is developed by integrating Si3N4/HZO/IGZO layers to realize three independent memory modes: electric long‐term, electric short‐term, and optical short‐term. This single‐device architecture functions as both a reservoir and readout layer, achieving 92.43% MNIST accuracy. It offers a fully hardware‐based,
Hyeonho Lee +9 more
wiley +1 more source
SNAP-25 disease variants affect synaptic transmission by destabilizing SNARE complexes within a multimeric SNARE ring. [PDF]
Vold VA +8 more
europepmc +1 more source

