Results 111 to 120 of about 1,906,626 (299)

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Bidirectional modulation of glutamatergic synaptic transmission by metabotropic glutamate type 7 receptors at Schaffer collateral-CA1 hippocampal synapses

, 2018
Neurotransmitter release is driven by Ca2+ influx at synaptic boutons that acts on synaptic vesicles ready to undergo exocytosis. Neurotransmitter release is inhibited when metabotropic glutamate type 7 (mGlu7) receptors provoke a reduction in Ca2 ...
Ricardo Martín, José Sánchez-Prieto, Martín Herranz, Ricardo, Rafael Luján, Andrea Collado-Alsina, José Javier Ferrero, Carolina Aguado, Aguado, Carolina, Torres Molina, Magdalena Isabel, Magdalena Torres, Collado-Alsina, Andrea, Sánchez-Prieto Borja, José, Luján, Rafael, Ferrero, José Javier, Martín, Ricardo, Sánchez-Prieto, José, Torres, Magdalena   +16 more
core   +1 more source

mGluR5-mediated astrocytes hyperactivity in the anterior cingulate cortex contributes to neuropathic pain in male mice

Communications Biology
Astrocytes regulate synaptic transmission in healthy and pathological conditions, but their involvement in modulating synaptic transmission in chronic pain is unknown.
Weida Shen, Fujian Chen, Yejiao Tang, Yulu Zhao, Linjing Zhu, Liyang Xiang, Li Ning, Wen Zhou, Yiran Chen, Liangxue Wang, Jing Li, Hui Huang, Ling-Hui Zeng   +12 more
doaj   +1 more source

Interface Dynamics in Biomolecular Condensates by High‐Speed AFM

Advanced Materials Interfaces, EarlyView.
High‐speed atomic force microscopy provides nanoscale structural dynamics at the liquid interface of biomolecular condensates, key elements in several cellular pathways. By addressing the challenges of low surface tension and condensate‐induced instabilities, we achieve nanometer spatial and sub‐second temporal resolution, revealing structural ...
Andreas Santamaria, Nessim Louafi, Isabelle Alakiki, Stephanie Hutin, Chloe Zubieta, Pierre‐Emmanuel Milhiet, Luca Costa   +6 more
wiley   +1 more source

Modulation of Synaptic Amplification in Sympathetic Ganglia [PDF]

, 2013
The purpose of this dissertation was to assess synaptic integration in neurons from the rat superior cervical ganglion (SCG) using complex temporal patterns of virtual synaptic activity that mimic in vivo conditions.
Springer, Mitchell
core  

Control of neural information transmission by synaptic dynamics

, 2002
The computational processing of a neural system is strongly influenced by the dynamical characteristics of the information transmission between neurons. In this work, the control of neural information transmission by synaptic dynamics is investigated by ...
Cartling, Bo,
core   +1 more source

Toward Perception‐Native Electronic Skin: Bio‐Inspired In‐/Near‐Sensor and Neuromorphic Computing for Humanoid Robots

Advanced Materials Technologies, EarlyView.
Dense tactile streams from across the humanoid body converge on collide in a central wiring and data bottleneck. By relocating computation closer to and then into the skin itself, near‐ and in‐sensor architectures, together with neuromorphic computing, chart a path toward perception‐native electronic skin, in which the conversion of stimulus into ...
Mijin Kim, Chang‐Jae Beak, Jiyoung Park, Youngdo Jung, Sunjong Oh, Sin‐Hyung Lee, Bo‐Yeon Lee   +6 more
wiley   +1 more source

Single‐Step Fabrication of Smart 3D Microstructures Exploiting Naphthopyrans as Photoinitiators and Photochromic Molecules

Advanced Optical Materials, EarlyView.
Naphthopyran–benzophenone compounds can act simultaneously as photoinitiators and photochromic molecules for two‐photon polymerization. Using a single‐step process, liquid photoresist is encapsulated within polymerized 3D microstructures, preserving reversible UV–vis photochromism after fabrication.
João P. Leote, Artur Andrishak, Paulo J. Coelho, José R. Fernandes, Christian Maibohm, Jana B. Nieder   +5 more
wiley   +1 more source

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

Advanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang, Hongyu Zhu, Wenqi Wang, Bingqian Shen, Yuanyuan Xin, Xingxing Song, Xuanyi Lu, Lixuan Li, Siting Chen, Xiaochen Zhang, Jialing Zeng, Haodong Zheng, Jianlong Lao, Ke Peng, Yixian Wei, Jiaming Zheng, Chuanhuo Hu, Xiaoye Wang, Xun Li   +18 more
wiley   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source