Results 201 to 210 of about 304,453 (323)

Update Disturbance‐Resilient Analog ReRAM Crossbar Arrays for In‐Memory Deep Learning Accelerators

Advanced Science, EarlyView.
Conductive metal oxide/HfOx analog ReRAM on 350 nm technology is presented for in‐memory deep learning accelerators. The device exhibits analog and nonvolatile conductance switching and high resilience to update disturbances, which is supported by COMSOL Multiphysics simulations.
Wooseok Choi, Tommaso Stecconi, Donato Francesco Falcone, Matteo Galetta, Victoria Clerico, Elisa Zaccaria, Mamidala Saketh Ram, Antonio La Porta, Folkert Horst, Daniel Jubin, Matias Senger, Marilyne Sousa, Steffen Reidt, Ralph Heller, Bernabe Linares‐Barranco, Valeria Bragaglia, Bert Jan Offrein   +16 more
wiley   +1 more source

Presenilin Loss Impairs Synaptic Transmission and Causes Axonal Degeneration through Ryanodine Receptor Dysfunction, Independent of γ-Secretase Activity. [PDF]

J Neurosci
Du X, Niu L, Ragan M, Fracz Z, Wang ZW.
europepmc   +1 more source

Formation of Condition‐Dependent Alpha‐Synuclein Fibril Strain in Artificial Cerebrospinal Fluid

Advanced Science, EarlyView.
α‐synuclein aggregation in artificial cerebrospinal fluid (aCSF) leads to a distinct conformation with an electron density pocket motif found in aggregates from PD and MSA patients. Such fibrils has low stability outside the reaction conditions, hinting about the influence of cerebrospinal fluid components not only on the formation, but also on the ...
Rūta Sniečkutė, Darius Šulskis, Arūnė Jocytė, Urtė Venclovaitė, Rimgailė Tamulytė, Mantas Žiaunys, Vytautas Smirnovas, Andrius Sakalauskas   +7 more
wiley   +1 more source

Endocannabinoid-mediated retrograde modulation of synaptic transmission

, 2014
Takako Ohno‐Shosaku, Masanobu Kano
openalex   +2 more sources

Optimizing Synaptic Architecture and Efficiency for High-Frequency Transmission [PDF]

, 2002
Holger Taschenberger, Ricardo M. Leão, Kevin Rowland, George A. Spirou, Henrique von Gersdorff   +4 more
openalex   +1 more source

Forelimb Motor Learning and Memory Consolidation Drives Distinct Oligodendrocyte Plasticity to Regulate Task‐related Neuronal Activity

Advanced Science, EarlyView.
Genetic and chemical tracking of oligodendrogenesis, combining fiber photometric neuronal activity recording, reveals that distinct oligodendrocyte plasticities are adopted during different phases of motor learning to fine‐tune task‐related neuronal activity, with a preferential involvement of oligodendrogenesis suppression and node lengthening (type 2
Shuming Wang, Nuo Xu, Wenwen Wang, Yongxiang He, Yuqian Yang, Liuning Zhang, Yanping Zou, Yuehua He, Huiliang Li, Liang Gao, Lin Xiao   +10 more
wiley   +1 more source

Cell-autonomous GABAARs are essential for NMDAR-mediated synaptic transmission, LTP, and spatial memory. [PDF]

EMBO Rep
Duan JJ, Jiang B, Yin W, Lin Y, Yan GM, Lu W.   +5 more
europepmc   +1 more source

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

Advanced Science, EarlyView.
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun, Yukai Wang, Man Wang, Xinyue Wang, Mingming Tang, Da Li, Jianhuan Qi, Xue Wang, Shujuan Sun, Lei Chen, Weibin An, Ligang Kong, Anqi Suo, Haibo Wang, Wenwen Liu, Lei Xu   +15 more
wiley   +1 more source

Gain of Alternative Allele Expression of LINC02449 at rs149707223 in Schizophrenia and Bipolar Disorder: Inducing Synaptic Transmission and Behavioral Deficits in Mice. [PDF]

Nat Commun
Yang T, Liu JM, Chen Q, Deng Z, Ni C, Wang Y, Lan Y, Jiang T, Li S, Jiang M, Xue H, Cao X, Wang Z, Zhao C.   +13 more
europepmc   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

Advanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi, Zesheng Li, Xin Sun, Yanfeng Yang, Yumin Luo, Ziang Song, Hengxin Dong, Lei Jin, Jing Xie, Yongzhi Shan, Guoguang Zhao   +10 more
wiley   +1 more source