Results 141 to 150 of about 91,819 (309)

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

tDCS improves early Alzheimer's disease by synaptic vesicle fusion and release. [PDF]

Mil Med Res
Zhuang YY, Yan JM, Wu TC, Xu WS, Wu B, Xie X, Wang WJ, Lin HW, Jian JW, Wang JZ, Jiang T, Chen LM, Qiu YX, Hu ZY, Zhou YH, Yang T, Yang MG, Zhu JF, Tao J, Chen LD, Li WG, Yan K, Liu WL.   +22 more
europepmc   +1 more source

eLife Assessment: Endosomal sorting protein SNX4 limits synaptic vesicle docking and release

Rafael Fernández‐Chacón
openalex   +1 more source

A catalytic independent function of the deubiquitinating enzyme USP14 regulates hippocampal synaptic short‐term plasticity and vesicle number

, 2013
Brandon J. Walters, Jada J. Hallengren, Christopher S. Theile, Hidde L. Ploegh, Scott M. Wilson, Lynn E. Dobrunz   +5 more
openalex   +2 more sources

Acute disruption of the synaptic vesicle membrane protein synaptotagmin 1 using knockoff in mouse hippocampal neurons

, 2020
Jason Vevea, Edwin R. Chapman
openalex   +1 more source

Next‐Generation Surgery: Integrating Artificial Intelligence, Genetic Technologies, Bioengineering and Rehabilitation Into Modern Practices

Exploration, EarlyView.
This graphic abstract depicts the convergence of artificial intelligence, genetic technologies, bioengineering, and rehabilitation as the core pillars of next‐generation surgery. These domains collectively enhance preoperative planning, intraoperative precision, tissue reconstruction, and postoperative recovery, driving a paradigm shift toward ...
Dengxiong Li, Jie Wang, Zhipeng Wang, Ruicheng Wu, Zhouting Tuo, Fanglin Shao, Wenjing Ge, Ziyu Shu, Yubo Yang, Dilinaer Wusiman, Qingxin Yu, Luxia Ye, Alisha Pati‐Alam, Facai Zhang, Koo Han Yoo, Susan Heavey, William C. Cho, Dechao Feng   +17 more
wiley   +1 more source

Selective, genetically induced increase in synaptic vesicle priming. [PDF]

Sci Adv
Aldahabi M, Balint F, Lorincz A, Lipstein N, Brose N, Nusser Z.   +5 more
europepmc   +1 more source

Integration of postmortem amygdala expression profiling, GWAS, and functional cell culture assays: neuroticism-associated synaptic vesicle glycoprotein 2A (SV2A) gene is regulated by miR-133a and miR-218

, 2020
Magdalena Jurkiewicz, Dirk Moser, Antonius Koller, Lei Yu, Emily I. Chen, David A. Bennett, Turhan Canli   +6 more
openalex   +1 more source

Biosensing With Nanofluidics

Exploration, EarlyView.
Nanofluidic biosensors employing in‐plane, out‐of‐plane, and free‐plane architectures transduce biomolecular information into fluidic signals through nanoscale manipulation of confined fluids, offering a quantitative and highly sensitive platform for biochemical detection. ABSTRACT Nanofluidics, the study of fluid transport confined within nanochannels
Qun Ma, Yan Xu
wiley   +1 more source