Results 121 to 130 of about 91,819 (309)

Faculty Opinions recommendation of v-SNARE composition distinguishes synaptic vesicle pools.

, 2012
Erwin Neher
openalex   +2 more sources

Microglial large extracellular vesicles propagate early synaptic dysfunction in Alzheimer’s disease [PDF]

, 2022
Martina Gabrielli, Ilaria Prada, Pooja Joshi, Chiara Falcicchia, Giulia D’Arrigo, Grazia Rutigliano, Elisabetta Battocchio, Rossella Zenatelli, Francesca Tozzi, Annalisa Radeghieri, Ottavio Arancio, Nicola Origlia, Claudia Verderio   +12 more
openalex   +1 more source

Transcranial Magnetic Stimulation as a Translational Biomarker in Early‐Phase Anti‐Seizure Medication Development: A Randomized, Double‐Blind, Placebo‐Controlled Study in Generalized Epilepsy

Clinical Pharmacology &Therapeutics, EarlyView.
One‐third of epilepsy patients remain treatment‐resistant, underscoring the need for novel anti‐seizure medications (ASMs) and reliable biomarkers of central target engagement. Cortical hyperexcitability is a hallmark of epilepsy, making excitability a valuable pharmacodynamic biomarker for early‐phase drug development supporting go/no‐go decision ...
Catherine M. E. de Cuba, Titia Q. Ruijs, Annika A. de Goede, Robert J. Doll, Maria Juachon, Michel J. A. M. van Putten, Geert Jan Groeneveld, Jules A. A. C. Heuberger   +7 more
wiley   +1 more source

Author response: Arf6 regulates the cycling and the readily releasable pool of synaptic vesicles at hippocampal synapse

, 2015
Erica Tagliatti, Manuela Fadda, Antonio Falace, Fabio Benfenati, Anna Fassio   +4 more
openalex   +1 more source

Synaptic Vesicle Localization within Axons

, 2019
Oligodendrocytes (OLs) are the myelinating cells in the central nervous system (CNS) that extend long branchy processes to explore many different neurons 1−4.
Hines, Jacob, Hobbs, Taylor
core  

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source

Nanoscale-targeted patch-clamp recordings of functional presynaptic ion channels

, 2013
Important modulatory roles have been attributed to presynaptic NMDA receptors (NMDARs) located on cerebellar interneuron terminals. Evidence supporting a presynaptic location includes an increase in the frequency of mini events following the application ...
Caldwell, M, Robertson, AD, Moss, GWJ, Benton, DCH, Smart, TG   +4 more
core  

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source

Tomosyn Inhibits Synaptic Vesicle Priming in Caenorhabditis elegans

, 2006
Elena O. Gracheva, Anna O. Burdina, Andrea Holgado, Martine Berthelot‐Grosjean, Brian D. Ackley, Gayla Hadwiger, Michael L. Nonet, Robby M. Weimer, Janet E. Richmond   +8 more
openalex   +2 more sources

Synapsin Controls Both Reserve and Releasable Synaptic Vesicle Pools during Neuronal Activity and Short-Term Plasticity inAplysia [PDF]

, 2001
Yann Humeau, Frédéric Doussau, Francesco Vitiello, Paul Greengard, Fabio Benfenati, Bernard Poulain   +5 more
openalex   +1 more source