Brain contains two forms of synaptic vesicle protein 2. [PDF]
, 1993 Sandra Bajjalieh +3 more
openalex +1 more source
Chameleonic Nature of Aβ: Implications for Alzheimer's and Other Amyloid Diseases
BioEssays, EarlyView.The energy landscape of Aβ reveals its flexible, “chameleon‐like” behavior, enabling diverse structures from disordered to β‐rich forms. This polymorphism facilitates aggregation, contributing to Alzheimer's disease progression, while the flat landscape also allows disaggregation, potentially slowing disease progression compared to prion proteins with ...
Birgit Strodel
wiley +1 more source
Selective MPP+ uptake into synaptic dopamine vesicles: possible involvement in MPTP neurotoxicity [PDF]
, 1993 Maria Del Zompo +5 more
openalex +1 more source
Deciphering the skeletal interoceptive circuitry to control bone homeostasis
BMEMat, EarlyView.This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu +7 more
wiley +1 more source
Calcium-dependent release of accumulated glutamate from synaptic vesicles within permeabilized nerve terminals [PDF]
, 1991 Phillip E. Kish, Tetsufumi Ueda
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Serotonergic Modulators in Alzheimer's Disease: A Hope in the Hopeless Condition
Chemistry &Biodiversity, EarlyView.ABSTRACT Alzheimer's disease (AD) is the main cause of dementia worldwide. AD is a progressive brain neurodegenerative disease due to genetic and environmental factors that induce a progressive accumulation of intracellular hyperphosphorylated tau protein and extracellular amyloid protein (Aβ).
Najlaa Hamed Almohmadi +7 more
wiley +1 more source
A new method for isolation and purification of fusion-competent inhibitory synaptic vesicles
Current Research in PhysiologySynaptic vesicles specific to inhibitory GABA-releasing neurons are critical for regulating neuronal excitability. To study the specific molecular composition, architecture, and function of inhibitory synaptic vesicles, we have developed a new method to ...
Nisha Gopal +5 more
doaj
Cholinergic synaptic vesicles are metabolically and biophysically heterogeneous even in resting terminals [PDF]
, 1990 V. P. Whittaker
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ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia +2 more
wiley +1 more source
The involvement of the synaptic vesicle cycle in homocysteine induced neurotoxicity in vitro and in vivo. [PDF]
Sci RepWang M +8 more
europepmc +1 more source