Results 181 to 190 of about 555,224 (393)
Ultrafast Multilevel Switching and Synaptic Behavior in a Planar Quantum Topological Memristor
Advanced Science, EarlyView.Dry‐transferred Bi2Te3 layers enable a planar quantum topological memristor framework. In‐plane topological surface states facilitate ultrafast & low‐power operations. Coexisting analog and digital modes support current‐controlled multilevel states. PQTM exhibits 105 s retention, 103 cycles endurance, and reproducibility across 24 devices.
Mamoon Ur Rashid +12 more
wiley +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Actomyosin-mediated inhibition of synaptic vesicle release under CB1R activation
Translational PsychiatryLong-term synaptic plasticity is critical for adaptive function of the brain, but presynaptic mechanisms of functional plasticity remain poorly understood.
Maureen H. McFadden +7 more
doaj +1 more source
Advanced Science, EarlyView.Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling +17 more
wiley +1 more source
Faculty Opinions recommendation of v-SNARE composition distinguishes synaptic vesicle pools.
, 2012 Erwin Neher
openalex +2 more sources
Isolation of 5‐hydroxytryptamine containing vesicles and of synaptic membranes from rat brain [PDF]
, 1969 W. Wesemann
openalex +1 more source
Advanced Science, EarlyView.Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély +5 more
wiley +1 more source
Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18
Neuron, 2017 Y. Lai +11 more
semanticscholar +1 more source