Results 171 to 180 of about 91,819 (309)

Safeguards of Neurotransmission: Endocytic Adaptors as Regulators of Synaptic Vesicle Composition and Function [PDF]

, 2017
Natalie Kaempf, Tanja Maritzen
openalex   +1 more source

Paternal Exposure to the Neonicotinoid Pesticide Clothianidin Alters Sperm MicroRNA Profiles in Mice and Intergenerationally Reduces Locomotor Activity in Male Offspring

Journal of Applied Toxicology, EarlyView.
ABSTRACT Accumulating evidence suggests that paternal environmental factors have epigenetic effects on sperm and influence offspring. Neonicotinoid pesticides (NNs), which are widely used around the world, are known to affect offspring phenotypes through maternal exposure in mice, but the effect of the paternal exposure remains unknown.
Makiko Ito, Tetsushi Hirano, Sarika Nunobiki, Ayano Yoshimoto, Yukako Hara, Yuya Ishida, Sakura Yonoichi, Youhei Mantani, Toshifumi Yokoyama, Yoshiaki Tabuchi, Yoshinori Ikenaka, Nobuhiko Hoshi   +11 more
wiley   +1 more source

Endocytic protein AP180 assembly domain regulates synaptic vesicle size and release in Caenorhabditis elegans. [PDF]

PLoS Biol
Wang Y, Wu L, Zhang L, Dong Y, Pant A, Liu Y, Bai J.   +6 more
europepmc   +1 more source

Tannic Acid Mitigates Monosodium Glutamate‐Induced Cortical Damage by Modulating Synaptic and Calcium‐Related Gene and Protein Expression

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neurotoxicity induced by excessive glutamatergic signaling is associated with synaptic dysfunction, calcium imbalance, and oxidative stress, which are key molecular events implicated in several neurodegenerative conditions. Monosodium glutamate (MSG), a common flavor enhancer, may exert neurotoxic effects, particularly on synaptic integrity ...
Medine Sibel Karagac, Enver Fehim Koçpinar, Hamid Ceylan   +2 more
wiley   +1 more source

Synaptic Vesicle Recycling Through the Lens of Ultrafast Endocytosis. [PDF]

Annu Rev Neurosci
Watanabe S.
europepmc   +1 more source

Alpha‐Synuclein Promotes Anterograde Vesicle Transport in Melanocytes and Melanoma Cells: A Pro‐Survival Function

Journal of the Chinese Chemical Society, EarlyView.
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley   +1 more source

Detection of Synaptic Vesicle Glycoprotein 2A in Serum Using a Polypyrrole-Functionalized Graphene Oxide Electrochemical Immunosensor. [PDF]

Nanomaterials (Basel)
Zhao Y, Li L, Tao J, Yang M, Li C, Zhang X, Zhang Y, Sun S, Zhao N.   +8 more
europepmc   +1 more source

A parametric electrophysiological–transcriptomic map of MscL‐G22S sonogenetic neuromodulation in the rat hippocampus: Toward precision ultrasound neuromodulation

Journal of Intelligent Medicine, EarlyView.
Using a factorial sweep of ultrasound fundamental and pulse repetition frequencies, we built a parametric electrophysiological–transcriptomic map of MscL‐G22S‐mediated hippocampal neuromodulation, providing reference data for precision, parameter‐aware ultrasound neuromodulation.
Xin Li, Bozhan Wang, Chenguang Zheng, Yutao Tian   +3 more
wiley   +1 more source

"Kiss-shrink-run" unifies mechanisms for synaptic vesicle exocytosis and hyperfast recycling. [PDF]

Science
Tao CL, Tian CL, Liu YT, Lu ZH, Qi L, Li XW, Li C, Shen X, Gu ML, Huang WL, Liu S, Yang LQ, Liao Z, Ma X, Wu J, Sun J, Wang P, Lau PM, Zhou ZH, Bi GQ.   +19 more
europepmc   +1 more source

Enriched Environment Enhances Motor Function in Mice With Cerebral Infarction by Promoting mTOR‐Dependent Autophagy in the Contralateral Dentate Nucleus

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Although environmental enrichment (EE) promotes post‐stroke motor recovery, the mechanisms underlying its regulation of cerebellar dentate nucleus (DN) plasticity remain unclear; this study therefore investigated how EE coordinates autophagy, mitochondrial homeostasis, and synaptic remodeling in the contralateral DN to facilitate functional ...
Chuan‐Jie Wang, Ke‐Wei Yu, Jun‐Fa Wu, Feng Tao   +3 more
wiley   +1 more source