Results 191 to 200 of about 91,819 (309)

Reduction in Synaptic Vesicle Protein Abundance but Increased Amounts of Nsg2 and Lpcat1 in Cerebral Cortices Without the Endosomal SNARE Proteins Vti1a and Vti1b. [PDF]

Proteomics
Gottschalk J, Kotschnew K, Hahn J, Patschkowski T, von Fischer von Mollard G.   +4 more
europepmc   +1 more source

Antibody-driven capture of synaptic vesicle proteins on the plasma membrane enables the analysis of their interactions with other synaptic proteins [PDF]

, 2019
Katharina N. Richter, Christina Patzelt, Nhu T. N. Phan, Silvio O. Rizzoli   +3 more
openalex   +1 more source

Co‐ and Multi‐Pathologies in Parkinson's Disease: An International Parkinson and Movement Disorder Society Scientific Issues Committee Review

Movement Disorders, EarlyView.
Abstract Parkinson's disease (PD) has been historically defined as a disease of striatal dopamine deficiency secondary to degeneration of dopaminergic neurons in the substantia nigra pars compacta, related to the presence of Lewy bodies and Lewy neurites.
Michele Matarazzo, Per Borghammer, Inas Elsayed, Jennifer G. Goldman, Yue Huang, Katja Lohmann, Per Svenningsson, Lorraine V. Kalia, Daniela Berg, Jeffrey H. Kordower, the MDS Scientific Issues Committee   +10 more
wiley   +1 more source

Synaptic vesicle glycoprotein 2 enables viable aneuploidy following centrosome amplification. [PDF]

Genetics
Blackmer JE, Jezuit EA, Chakraborty A, Yalamanchi SN, Montague RA, Dickert EE, Peterson NG, Outlaw W, Fox DT.   +8 more
europepmc   +1 more source

Depletion of microglial compensation in glial network: Disease‐associated response dynamics in the revised amyloid hypothesis

Neuroprotection, EarlyView.
The critical transition from amyloid pathology to irreversible neuronal loss in Alzheimer's disease hinges on the microglial response. This review aims to systematize the patterns of how microglia react within the glial context. Abstract Microglia mount coordinated, stage‐dependent compensatory programs in response to early amyloid β (Aβ) accumulation ...
Songtao Lei, Zixuan Huang, Wen Wang, Yan Meng   +3 more
wiley   +1 more source

Imaging Synaptic Vesicle Protein SV2C with ¹⁸ F-UCB-F: An In Vitro Autoradiography and In Vivo NHP PET Study [PDF]

S. Nag, V. C. Sousa, Rongfeng Zou, A. F. Morén, Prodip Datta, Y. K. Meynaq, Anne Valade, Céline Vermeiren, Philippe Motté, Joël Mercier, H. Ågren, C. Halldin, A. Varrone   +12 more
openalex   +1 more source

Colocalization of synapsin and actin during synaptic vesicle recycling [PDF]

, 2003
Ona Bloom, Emma Evergren, N.V. Tomilin, Ole Kjærulff, Péter Lőw, Lennart Brodin, Vincent A. Pieribone, Paul Greengard, Oleg Shupliakov   +8 more
openalex   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

Initial Distance-Dependent Mean Force Drives Synaptic Vesicle Motion Toward Fusion Sites in Stimulated Hippocampal Neurons. [PDF]

Adv Sci (Weinh)
Park G, Kim JH, Lee H, Park C, Chen S, Bates L, Sung J, Park H.   +7 more
europepmc   +1 more source

Proteomic Profiling of Primary Hippocampal Neurons Reveals Noncanonical GFAP Expression and Metabolic Adaptations in Glia‐Free Culture

PROTEOMICS, EarlyView.
ABSTRACT Despite their widespread use as a research model, a comprehensive, quantitative proteomic profile of the cultured hippocampal neurons has remained unexplored. Here, we provide the first global proteomic characterization of primary murine hippocampal neurons cultured for 14 days under near‐physiological glucose conditions (2.5 mM).
Dominika Drulis‐Fajdasz, Kinga Gostomska‐Pampuch, Natalia Pudełko‐Malik, Mariusz Fleszar, Agnieszka Gizak, Jacek R. Wiśniewski, Dariusz Rakus   +6 more
wiley   +1 more source