Results 181 to 190 of about 91,819 (309)

Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons. [PDF]

Nat Commun
Kroll J, Kravčenko U, Sadeghi M, Diebolder CA, Ivanov L, Lubas M, Sprink T, Schacherl M, Kudryashev M, Rosenmund C.   +9 more
europepmc   +1 more source

Working Memory Impairment in Calcineurin Knock-out Mice Is Associated with Alterations in Synaptic Vesicle Cycling and Disruption of High-Frequency Synaptic and Network Activity in Prefrontal Cortex [PDF]

, 2013
Jeffrey R. Cottrell, Jonathan M. Levenson, Sung Hyun Kim, Helen E. Gibson, Kara Richardson, Michael Sivula, Bing Li, Crystle J. Ashford, K. A. Heindl, Ryan J. Babcock, David M. Rose, Chris M. Hempel, Kjesten A. Wiig, Pascal Laeng, Michael E. Levin, Timothy A. Ryan, David J. Gerber   +16 more
openalex   +1 more source

METTL14 Ameliorates Mitochondrial Dysfunction and Autophagy in Lens Epithelial Cells of Diabetic Cataracts via m6A Modification of RPL3

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cataracts are a leading cause of blindness, with lens epithelial cells (LECs) exhibiting mitochondrial dysfunction and autophagy inhibition under high glucose (HG) conditions. Methyltransferase‐like 14 (METTL14), an RNA methyltransferase, regulates N6‐methyladenosine (m6A) RNA modification; however, its role in modulating ...
Rui Li, Xue Wang, Wei Du, Qian Li, Hong‐Ping Cui   +4 more
wiley   +1 more source

Synaptic Vesicle Recycling at the Developing Presynapse. [PDF]

J Neurochem
Kim N, Cousin MA.
europepmc   +1 more source

miR‐9 Restricts Insulin Secretion by Targeting Rab34, Which Mediates Lysosomal Degradation of Proinsulin

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Insulin secretion is a complex, vesicular transport process. Rab34 is a key regulator of intracellular vesicle transport; however, its role in insulin secretion has not yet been reported. miRNA‐9 is vital for the development and progression of the diagnosis and treatment of type 2 diabetes. This study aimed to investigate whether miR‐9 targets
Zhen‐Zhen Guo, Ao‐Ying Li, Ting‐Ting Xiang, Zu‐Hao Zhang, Ao Deng, Yang Han   +5 more
wiley   +1 more source

Phosphorylation of presynaptic PLPPR3 controls synaptic vesicle release. [PDF]

iScience
Kroon C, Bareesel S, Perez GA, Nagy-Herczeg D, Ranti D, Syropoulou V, Coveney S, Kirchner M, Gimber N, Bintig W, Brosig A, Braune G, Textoris-Taube K, Zolnik TA, Mertins P, Schmoranzer J, Milovanovic D, Leondaritis G, Eickholt BJ.   +18 more
europepmc   +1 more source

Decision letter: Mitochondrial support of persistent presynaptic vesicle mobilization with age-dependent synaptic growth after LTP

, 2015

openalex   +1 more source

Synaptic vesicles transiently dock to refill release sites [PDF]

, 2018
Grant F. Kusick, Morven Chin, Sumana Raychaudhuri, Kristina Lippmann, Kadidia P. Adula, Edward J. Hujber, Thien N. Vu, M. Wayne Davis, Erik M. Jørgensen, Shigeki Watanabe   +9 more
openalex   +1 more source

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz, Marina Farah, Laura Silveira‐Moriyama   +2 more
wiley   +1 more source

Establishment of a novel lipid and content mixing assay to resolve the regulatory effect of Munc18-1 and CpxII on SNARE-mediated membrane fusion of reconstituted VAMP2/Syt1 SUVs and isolated rat brain synaptic vesicles.

, 2015
Maximilian Pfau
openalex   +1 more source