Results 211 to 220 of about 555,224 (393)

Human Brain Contusions Contain Pathogenic Transmissible Species that Induce Progressive Cognitive Decline and Tau Pathology in Mice

Annals of Neurology, EarlyView.
Objective Traumatic brain injury (TBI) is an established risk factor for dementia, although the underlying mechanisms remain unclear. Our previous research demonstrated that a single severe TBI in wild‐type (WT) mice induces a prion‐like form of tau (tauTBI) that spreads throughout the brain, leading to memory deficits.
Gloria Vegliante, Francesca Pischiutta, Elena Restelli, Federico Moro, Maria Antonietta Chiaravalloti, Ilaria Raimondi, Ilaria Bertani, Ilaria Lisi, Eliana Sammali, Rosaria Pascente, Serena Scozzari, Laura Pasetto, Carly Douglas, Marco Locatelli, Fabrizio Ortolano, Valentina Bonetto, David J. Loane, Nino Stocchetti, Roberto Chiesa, Elisa R. Zanier   +19 more
wiley   +1 more source

Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons. [PDF]

Nat Commun
Kroll J, Kravčenko U, Sadeghi M, Diebolder CA, Ivanov L, Lubas M, Sprink T, Schacherl M, Kudryashev M, Rosenmund C.   +9 more
europepmc   +1 more source

Synaptic Vesicle Recycling Through the Lens of Ultrafast Endocytosis. [PDF]

Annu Rev Neurosci
Watanabe S.
europepmc   +1 more source

Redox‐Activated Probes Enable High‐Contrast Live Imaging of Native Postsynaptic Scaffolds

Angewandte Chemie International Edition, EarlyView.
Sylives are modified fluorescent peptides for high‐contrast live imaging of inhibitory (gephyrin) and excitatory (PSD‐95) postsynaptic scaffolds in native neurons. Clean labeling requires low nanomolar probe levels, whereas uptake needs micromolar cell‐penetrating peptide (CPP).
Christiane Huhn, Clémence Mille, Sheng‐Yang Ho, Felix Lützenkirchen, Vladimir Khayenko, Melanie Hein, Christian Werner, Matthias Kneussel, Johannes W. Hell, Christian G. Specht, Hans M. Maric   +10 more
wiley   +1 more source

Synaptic Vesicle Recycling at the Developing Presynapse. [PDF]

J Neurochem
Kim N, Cousin MA.
europepmc   +1 more source

Non-invasive force measurement reveals the number of active kinesins on a synaptic vesicle precursor in axonal transport regulated by ARL-8

, 2018
Kumiko Hayashi, Shin Hasegawa, Takashi Sagawa, Sohei Tasaki, Shinsuke Niwa   +4 more
openalex   +2 more sources

Synaptic Vesicle Endocytosis Occurs on Multiple Timescales and Is Mediated by Formin-Dependent Actin Assembly [PDF]

, 2017
Tolga Soykan, Natalie Kaempf, Takeshi Sakaba, Dennis Vollweiter, Felix Goerdeler, Dmytro Puchkov, Natalia L. Kononenko, Volker Haucke   +7 more
openalex   +1 more source

Synaptic vesicle pools are a major hidden resting metabolic burden of nerve terminals

, 2021
Camila Pulido, Timothy A. Ryan
openalex   +1 more source

The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam.

Proceedings of the National Academy of Sciences of the United States of America, 2004
B. Lynch, N. Lambeng, K. Nocka, Patricia Kensel-Hammes, S. Bajjalieh, A. Matagne, B. Fuks   +6 more
semanticscholar   +1 more source

Mechanisms Underlying Allosteric Modulation of Antiseizure Medication Binding to Synaptic Vesicle Protein 2A (SV2A) [PDF]

Anshumali Mittal, Matthew F. Martin, Laurent Provins, Adrian Hall, Marie Ledecq, Christian Wolff, Michel Gillard, P.S. Horanyi, Jonathan A. Coleman   +8 more
openalex   +1 more source