Results 251 to 260 of about 91,819 (309)

Proteostasis of organelles in aging and disease

The FEBS Journal, EarlyView.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi, Cansu Doğan, Dunja Petrović, Gülce Perçin, Seda Koyuncu, David Vilchez   +5 more
wiley   +1 more source

Correction for Mittal et al., Mechanisms underlying allosteric modulation of antiseizure medication binding to synaptic vesicle protein 2A (SV2A). [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Endosomal sorting protein SNX4 limits synaptic vesicle docking and release. [PDF]

Elife
Poppinga J, Barrett NJ, Cornelisse LN, Verhage M, van Weering JRT.   +4 more
europepmc   +1 more source

Harnessing synaptic vesicle release and recycling with antibody shuttle for targeted delivery of therapeutics to neurons. [PDF]

Mol Ther Methods Clin Dev
Yee KKL, Kumamoto J, Inomata D, Suzuki N, Harada R, Yumoto N.   +5 more
europepmc   +1 more source

α-Synuclein-Assembled Synaptic Vesicle Pools at the Presynaptic Terminal: A Study of α-Synuclein Function Using a Novel Mouse Model. [PDF]

Acta Histochem Cytochem
Suzuki C, Yamaguchi J, Tanida I, Uchiyama Y.   +3 more
europepmc   +1 more source

CryoVesNet: A dedicated framework for synaptic vesicle segmentation in cryo-electron tomograms. [PDF]

J Cell Biol
Khosrozadeh A, Seeger R, Witz G, Radecke J, Sørensen JB, Zuber B.   +5 more
europepmc   +1 more source

Persistence of quantal synaptic vesicle recycling in virtual absence of dynamins. [PDF]

J Physiol
Afuwape OAT, Chanaday NL, Kasap M, Monteggia LM, Kavalali ET.   +4 more
europepmc   +1 more source

Cerebrospinal fluid and brain positron emission tomography measures of synaptic vesicle glycoprotein 2A: Biomarkers of synaptic density in Alzheimer's disease. [PDF]

Alzheimers Dement
Mecca AP, Ashton NJ, Chen MK, O'Dell RS, Toyonaga T, Zhao W, Young JJ, Salardini E, Bates KA, Ra J, Goodcase S, Silva-Rudberg JA, Nabulsi NB, Brinkmalm A, Kvartsberg H, Schöll M, Nilsson J, Arnsten AFT, Huang Y, Hansson O, Zetterberg H, Carson RE, Blennow K, van Dyck CH.   +23 more
europepmc   +1 more source

Nanobinders for Synaptotagmin 1 enable the analysis of synaptic vesicle dynamics in rodent and human models

Goel R, Jevdokimenko K, Rehm R, Hentze J, Agüi-Gonzalez P, Ninov M, Lange F, Witkowska A, Bolz S, Pennacchietti F, Damenti M, Kaempf N, Khayenko V, Calatayud C, Malviya VN, Chanaday NL, Hutchinson ES, Liu H, Weyand K, Ivanova D, Wallis TP, Small C, Maric HM, Joensuu M, Cousin MA, Meunier FA, Verstreken P, Testa I, Kavalali ET, Haucke V, Jakobs S, Urlaub H, Brose N, Cooper BH, Stenmark P, Opazo F, Jahn R, Rizzoli SO, Fornasiero EF.   +38 more
europepmc   +1 more source