Results 271 to 280 of about 634,741 (343)

Prenatal Environmental Hypoxia Enhances Adult Hypoxia Tolerance in Brandt's Voles (Lasiopodomys brandtii): Behavioral and Transcriptomic Insights

Integrative Zoology, EarlyView.
Prenatal hypoxia enhances adult hypoxia tolerance in Brandt's voles, preserving cognitive and memory functions. Transcriptomic analysis reveals adaptive changes in energy metabolism, oxygen transport, and neuroprotective mechanisms, highlighting developmental plasticity.
Mengyang Li, Congcong Qiao, Xiujuan Li, Maolin Huang, Zhenlong Wang, Luye Shi   +5 more
wiley   +1 more source

α-Synuclein-Assembled Synaptic Vesicle Pools at the Presynaptic Terminal: A Study of α-Synuclein Function Using a Novel Mouse Model. [PDF]

Acta Histochem Cytochem
Suzuki C, Yamaguchi J, Tanida I, Uchiyama Y.   +3 more
europepmc   +1 more source

Decoding Dual Regulatory Layers: Integrating Differential Expression and Alternative Splicing Dynamics in the Evolution of Laryngeal Echolocation Across Chiropteran Lineages

Integrative Zoology, EarlyView.
We integrated short‐read and long‐read RNA‐seq data from cochlear tissues of echolocating and non‐echolocating bats to disentangle transcriptional and post‐transcriptional regulation. Echolocating bats showed neural‐function enrichment among differentially expressed genes, while alternatively spliced genes were linked to epigenetic regulation. Overlaps
Jianyu Wu, Daoyuan Hu, Min Chen, Xiuguang Mao   +3 more
wiley   +1 more source

CryoVesNet: A dedicated framework for synaptic vesicle segmentation in cryo-electron tomograms. [PDF]

J Cell Biol
Khosrozadeh A, Seeger R, Witz G, Radecke J, Sørensen JB, Zuber B.   +5 more
europepmc   +1 more source

Pineal Gland Volume, Sleep Quality, and Psychiatric Disorders: A Systematic Review and Meta‐Analysis

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Disturbances in sleep and circadian rhythms are features of several psychiatric disorders. The pineal gland regulates these rhythms via melatonin, with pineal gland volume (PGV) serving as a structural proxy. We conducted a meta‐analysis to synthesize evidence on differences in PGV between patients with psychiatric disorders and ...
Sophie Bolwig, Kristian H. R. Jensen
wiley   +1 more source

Cerebrospinal fluid and brain positron emission tomography measures of synaptic vesicle glycoprotein 2A: Biomarkers of synaptic density in Alzheimer's disease. [PDF]

Alzheimers Dement
Mecca AP, Ashton NJ, Chen MK, O'Dell RS, Toyonaga T, Zhao W, Young JJ, Salardini E, Bates KA, Ra J, Goodcase S, Silva-Rudberg JA, Nabulsi NB, Brinkmalm A, Kvartsberg H, Schöll M, Nilsson J, Arnsten AFT, Huang Y, Hansson O, Zetterberg H, Carson RE, Blennow K, van Dyck CH.   +23 more
europepmc   +1 more source

Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Persistence of quantal synaptic vesicle recycling in virtual absence of dynamins. [PDF]

J Physiol
Afuwape OAT, Chanaday NL, Kasap M, Monteggia LM, Kavalali ET.   +4 more
europepmc   +1 more source

Rasopathy-Associated Mutation Ptpn11^D61Y has Age-Dependent Effect on Synaptic Vesicle Recycling. [PDF]

Cell Mol Neurobiol
Guhathakurta D, Selzam F, Petrušková A, Weiss EM, Akdaş EY, Montenegro-Venegas C, Zenker M, Fejtová A.   +7 more
europepmc   +1 more source

Kif1a and intact microtubules maintain synaptic-vesicle populations at ribbon synapses in zebrafish hair cells. [PDF]

J Physiol
David S, Pinter K, Nguyen KK, Lee DS, Lei Z, Sokolova Y, Sheets L, Kindt KS.   +7 more
europepmc   +1 more source