Results 261 to 270 of about 107,361 (347)

Secretome Profiling in Axon Regeneration: Emerging Techniques and Therapeutic Translation

Sensory Neuroscience, EarlyView.
ABSTRACT The secretome refers to the in vivo ensemble of molecular entities that are found in interstitial spaces. It is then the mere secreted products of the cells, as all biomolecules in the interstitial cellular spaces also undergo modifications. The fractionated secretome may hold potential as a cell‐free therapy option due to its role in tissue ...
Maria D. Cabrera, Nicole Ramones, Isabella Moceri, Sanjoy K. Bhattacharya   +3 more
wiley   +1 more source

Assessing non-invasive quantitative methods for [¹⁸F]SynVesT-1 PET imaging of synaptic vesicle glycoprotein 2A in the rat brain. [PDF]

Eur J Nucl Med Mol Imaging
Berckmans L, Schrauwen C, Miranda A, Staelens S, Bertoglio D.   +4 more
europepmc   +1 more source

Conductive Materials and Electrical Stimulation for Auditory Restoration

Sensory Neuroscience, EarlyView.
Applications of electroconductive biomaterials and electrical stimulation in cochlear tissue engineering.(1) Enable auditory neural repair through conductive materials and electrical stimulation, enhancing neuron survival and synaptic plasticity.(2) Integrate optogenetic‐electrical systems and cochlear organoid platforms for frequency‐specific ...
Menghui Liao, Yuyang Qiu, Qian Zhu, Ziyi Wang, Hong Cheng, Bin Zhang, Cheng Cheng, Lei Tian, Yangnan Hu   +8 more
wiley   +1 more source

Nanobinders for Synaptotagmin 1 enable the analysis of synaptic vesicle dynamics in rodent and human models

Goel R, Jevdokimenko K, Rehm R, Hentze J, Agüi-Gonzalez P, Ninov M, Lange F, Witkowska A, Bolz S, Pennacchietti F, Damenti M, Kaempf N, Khayenko V, Calatayud C, Malviya VN, Chanaday NL, Hutchinson ES, Liu H, Weyand K, Ivanova D, Wallis TP, Small C, Maric HM, Joensuu M, Cousin MA, Meunier FA, Verstreken P, Testa I, Kavalali ET, Haucke V, Jakobs S, Urlaub H, Brose N, Cooper BH, Stenmark P, Opazo F, Jahn R, Rizzoli SO, Fornasiero EF.   +38 more
europepmc   +1 more source

Integrative single-cell RNA sequencing and mendelian randomization analysis reveal the potential role of synaptic vesicle cycling-related genes in Alzheimer's disease. [PDF]

J Prev Alzheimers Dis
Zeng J, Zhang R, Xu H, Zhang C, Lu L.
europepmc   +1 more source

Astrocyte Lipid Droplet Dynamics Orchestrate Neurological Disorders and Therapeutic Horizons

Small Science, EarlyView.
This review examines astrocyte lipid droplet (LD) metabolism in neurological disorders, including Alzheimer's disease, stroke, epilepsy, and glioma. It analyzes regulatory mechanisms governing LD formation, transport, and degradation in astrocytes, highlighting their potential as biomarkers and therapeutic targets through integrative multiomics ...
Jiani Zhong, Yanyi Peng, Lingyue Zhang, Bo Xiao, Mengqi Zhang   +4 more
wiley   +1 more source

Self‐Driving Microscopes: AI Meets Super‐Resolution Microscopy

Small Methods, EarlyView.
This review examines the use of machine learning to automate super‐resolution optical microscopy, enabling the microscope to autonomously make decisions on what, when, and how to image. By eliminating the need for human intervention, this approach has the potential to enhance the versatility and accessibility of super‐resolution microscopy.
Edward N. Ward, Anna Scheeder, Max Barysevich, Clemens F. Kaminski   +3 more
wiley   +1 more source

Mild Zika Virus Infection in Mice Without Motor Impairments Induces Working Memory Deficits, Anxiety-like Behaviors, and Dysregulation of Immunity and Synaptic Vesicle Pathways. [PDF]

Viruses
Chivatá-Ávila JA, Rojas-Estevez P, Muñoz-Suarez AM, Caro-Morales E, Rengifo AC, Torres-Fernández O, Lozano JM, Álvarez-Díaz DA.   +7 more
europepmc   +1 more source

Glutamate uptake occurs at an early stage of synaptic vesicle recycling

, 1997
Ian A. Prior, Michael J. Clague
openalex   +1 more source

Review of published research on primary dysautonomia of domestic animals

Veterinary Record, EarlyView.
Abstract An article published in 1992 by Marion M. Pollin and I.R. Griffiths reviewed the topic of primary dysautonomias of the autonomic nervous system of unidentified origin in multiple domestic species, specifically cats, dogs and horses. Thirty‐one years later, we appear no closer to identifying the causal agents of these strikingly similar ...
Tanith Harte, David Smith, Jo Moore, Beth Wells   +3 more
wiley   +1 more source