Results 331 to 340 of about 555,224 (393)
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Annual Review of Neuroscience, 2004
▪ Abstract Neurotransmitter release is mediated by exocytosis of synaptic vesicles at the presynaptic active zone of nerve terminals. To support rapid and repeated rounds of release, synaptic vesicles undergo a trafficking cycle. The focal point of the vesicle cycle is Ca2+-triggered exocytosis that is followed by different routes of endocytosis and ...
T. Sūdhof
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▪ Abstract Neurotransmitter release is mediated by exocytosis of synaptic vesicles at the presynaptic active zone of nerve terminals. To support rapid and repeated rounds of release, synaptic vesicles undergo a trafficking cycle. The focal point of the vesicle cycle is Ca2+-triggered exocytosis that is followed by different routes of endocytosis and ...
T. Sūdhof
semanticscholar +3 more sources
Annual Review of Cell and Developmental Biology, 1999
▪ Abstract Synaptic vesicles, which have been a paradigm for the fusion of a vesicle with its target membrane, also serve as a model for understanding the formation of a vesicle from its donor membrane. Synaptic vesicles, which are formed and recycled at the periphery of the neuron, contain a highly restricted set of neuronal proteins.
M J, Hannah, A A, Schmidt, W B, Huttner
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▪ Abstract Synaptic vesicles, which have been a paradigm for the fusion of a vesicle with its target membrane, also serve as a model for understanding the formation of a vesicle from its donor membrane. Synaptic vesicles, which are formed and recycled at the periphery of the neuron, contain a highly restricted set of neuronal proteins.
M J, Hannah, A A, Schmidt, W B, Huttner
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Nature Reviews Neuroscience, 2005
Communication between cells reaches its highest degree of specialization at chemical synapses. Some synapses talk in a 'whisper'; others 'shout'. The 'louder' the synapse, the more synaptic vesicles are needed to maintain effective transmission, ranging from a few hundred (whisperers) to nearly a million (shouters).
Silvio O, Rizzoli, William J, Betz
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Communication between cells reaches its highest degree of specialization at chemical synapses. Some synapses talk in a 'whisper'; others 'shout'. The 'louder' the synapse, the more synaptic vesicles are needed to maintain effective transmission, ranging from a few hundred (whisperers) to nearly a million (shouters).
Silvio O, Rizzoli, William J, Betz
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Toxicon, 2008
Neurotransmitter release from presynaptic nerve endings is mediated by Ca2+-dependent exocytosis of synaptic vesicles. During the past 15 years, major progress has been made in unravelling the molecular mechanisms underlying exocytosis and the recycling of synaptic vesicles.
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Neurotransmitter release from presynaptic nerve endings is mediated by Ca2+-dependent exocytosis of synaptic vesicles. During the past 15 years, major progress has been made in unravelling the molecular mechanisms underlying exocytosis and the recycling of synaptic vesicles.
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Formation of synaptic vesicles
Current Opinion in Cell Biology, 1994Synaptic vesicles (SVs) are specialized secretory organelles used for the fast and focal signaling between nerve cells. They are small and homogeneous in size (50 nm), and contain non-peptide neurotransmitters such as glutamate, gamma-aminobutyric acid (GABA) and acetylcholine. The exocytosis of SVs occurs at low rates in resting nerve terminals and is
O, Mundigl, P, De Camilli
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Isolation of Synaptic Vesicles
Current Protocols in Cell Biology, 2004AbstractSynaptic vesicles are the most abundant secretory organelle in eukaryotic neural cells. Synaptic vesicles are physically distinct from other membrane‐bound organelles because they are small, spherical, and highly uniform in size with a diameter of about 40 nm.
Branch, Craige +2 more
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Biogenesis of synaptic vesicles
Journal of Cell Science, 1993ABSTRACT The basic endosomal recycling pathway can be modified to generate transcytotic vesicles, storage vesicles and synaptic vesicles. Sorting into synaptic vesicles requires specialized sorting information not present in the transcytotic and storage vesicle proteins.
R B, Kelly +5 more
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Annual Review of Physiology, 1998
▪ Abstract The ins and outs of the synaptic vesicle cycle are being examined in increasing detail with diverse investigative tools in a variety of cell types, particularly those with large granules. The cycle begins with the opening of a fusion pore that connects the vesicle lumen to the extracellular fluid.
W J, Betz, J K, Angleson
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▪ Abstract The ins and outs of the synaptic vesicle cycle are being examined in increasing detail with diverse investigative tools in a variety of cell types, particularly those with large granules. The cycle begins with the opening of a fusion pore that connects the vesicle lumen to the extracellular fluid.
W J, Betz, J K, Angleson
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Synaptic Vesicles and Exocytosis
Annual Review of Neuroscience, 1994Neurons transmit information by releasing neurotransmitters from presynaptic nerve endings, In the resting stage , transmitters are stored in small organelles of uniform size and shape , the synaptic vesicles . When an action potential arrives in the nerve terminal , the membrane depolarizes and voltage-gated Ca2+ channels open .
R, Jahn, T C, Südhof
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