Results 61 to 70 of about 107,361 (347)
Synaptic Vesicle Pools and Dynamics [PDF]
Cold Spring Harbor Perspectives in Biology, 2012 Synaptic vesicles release neurotransmitter at chemical synapses, thus initiating the flow of information in neural networks. To achieve this, vesicles undergo a dynamic cycle of fusion and retrieval to maintain the structural and functional integrity of the presynaptic terminals in which they reside.
Richard W. Tsien, AbdulRasheed A. Alabi
openaire +3 more sources
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
A novel synaptic vesicle fusion path in the rat cerebral cortex: the "saddle" point hypothesis. [PDF]
PLoS ONE, 2014 We improved freeze-fracture electron microscopy to study synapses in the neuropil of the rat cerebral cortex at ∼2 nm resolution and in three-dimensions.
Guido A Zampighi +2 more
doaj +1 more source
, 2019 The cellular and the molecular mechanisms by which long noncoding RNAs (lncRNAs) may regulate presynaptic function and neuronal activity are largely unexplored.
Bansal, V. +13 more
core +1 more source
Long Term Potentiation (LTP) and Long Term Depression (LTD) Cause Differential Spatial Redistribution of the Synaptic Vesicle Protein Synaptophysin in the Middle Molecular Layer of the Dentate Gyrus in Rat Hippocampus [PDF]
, 2016 The presynaptic modifications that accompany long-term changes in synaptic plasticity are still not fully understood. Synaptophysin is a major synaptic vesicle protein involved in neurotransmitter release. We have used quantitative electron microscopy to
Chaudhury, Sraboni +5 more
core +1 more source
Advanced Functional Materials, EarlyView.This study introduces a conductive nerve guidance conduit integrated with wireless electrical stimulation through alternating magnetic fields, which induces currents and creates a supportive microenvironment for nerve regeneration. In vivo studies show that this approach significantly enhanced myelin restoration, gastrocnemius muscle regeneration ...
Shiheng Liu +7 more
wiley +1 more source
Vesicle Clustering in a Living Synapse Depends on a Synapsin Region that Mediates Phase Separation
Cell Reports, 2020 Summary: Liquid-liquid phase separation is an increasingly recognized mechanism for compartmentalization in cells. Recent in vitro studies suggest that this organizational principle may apply to synaptic vesicle clusters. Here we test this possibility by
Arndt Pechstein +8 more
doaj
A mouse model of autism implicates endosome pH in the regulation of presynaptic calcium entry. [PDF]
, 2018 Psychoactive compounds such as chloroquine and amphetamine act by dissipating the pH gradient across intracellular membranes, but the physiological mechanisms that normally regulate organelle pH remain poorly understood.
Bendor, Jacob +10 more
core +3 more sources
Scattering synaptic vesicles [PDF]
The Journal of Cell Biology, 2006 ![][1] The BDNF-induced increase (left) in synapses (red) on a neuron (green) is lost if β-catenin and cadherin are locked together (right). Synaptic vesicles get dispersed to new sites, according to Bamji et al.
openaire +2 more sources
Biointerfacing with AgBiS2 Quantum Dots for Pseudocapacitive Photostimulation
Advanced Functional Materials, EarlyView.It is demonstrated that AgBiS2 quantum dots exhibit unique photoinduced pseudocapacitive charge transfer properties, enabling efficient light‐to‐electrical energy conversion. These quantum dots facilitate enhanced light absorption and transduction when integrated with ZnO nanowires, which serve as an effective charge transport medium.
Ridvan Balamur +8 more
wiley +1 more source