Results 41 to 50 of about 297,963 (299)

Mathematical modeling of the Drosophila neuromuscular junction [PDF]

, 2009
Poster presentation: An important challenge in neuroscience is understanding how networks of neurons go about processing information. Synapses are thought to play an essential role in cellular information processing however quantitative and mathematical ...
Queisser, Sean Gillian, Bucher, Daniel, Schuster, Christoph M., Wittum, Gabriel, Knodel, Markus Michael   +4 more
core   +1 more source

Structure-function study of mammalian Munc18-1 and C. elegans UNC-18 implicates domain 3b in the regulation of exocytosis [PDF]

, 2011
This work was supported by grants from the Wellcome Trust and BBSRC. GRP was supported by a Wellcome Trust Prize Studentship. The C. elegans strain used in this work was provided by the Caenorhabditis Genetics Center, which is funded by the National ...
Haynes, Lee P., Burgoyne, Robert D., Walmesley Alice, Burgoyne Robert D., James R Johnson, Gerald R. Prescott, Barclay, Jeff W., Robert D. Burgoyne, Johnson James R., James R. Johnson, Prescott, Gerald R., Gerald R Prescott, Lee P. Haynes, Morgan, Alan, Margaret E Graham, Walmesley, Alice, Johnson, James R., Jeff W Barclay, Prescott Gerald R., Jeff W. Barclay, Lee P Haynes, Jones Mathew, Graham, Margaret E., Morgan Alan, Margaret E. Graham, Jones, Mathew, Alan Morgan, Barclay Jeff W., Robert D Burgoyne, Mathew Jones, Graham Margaret E., Haynes Lee P., Alice Walmesley   +32 more
core   +1 more source

Clarinet (CLA-1), a novel active zone protein required for synaptic vesicle clustering and release

eLife, 2017
Active zone proteins cluster synaptic vesicles at presynaptic terminals and coordinate their release. In forward genetic screens, we isolated a novel Caenorhabditis elegans active zone gene, clarinet (cla-1).
Zhao Xuan, Laura Manning, Jessica Nelson, Janet E Richmond, Daniel A Colón-Ramos, Kang Shen, Peri T Kurshan   +6 more
doaj   +1 more source

Recycling of Synaptic Vesicles

, 1997
Publisher Summary A widely accepted model describes the synaptic vesicle cycle as a modification of the receptor-mediated recycling pathway present in all cells. This pathway, by which cell surface receptors, like transferrin or low-density lipoprotein receptors, are internalized and recycled back to the surface, involves two distinct vesicular ...
R, Bauerfeind, C, David, D, Grabs, P S, McPherson, Y, Nemoto, V I, Slepnev, K, Takei, P, De Camilli   +7 more
openaire   +2 more sources

Molecular Aspects of Secretory Granule Exocytosis by Neurons and Endocrine Cells [PDF]

, 1994
Neuronal communication and endocrine signaling are fundamental for integrating the function of tissues and cells in the body. Hormones released by endocrine cells are transported to the target cells through the circulation.
MANFRED GRATZL, Gratzl, Manfred
core   +1 more source

Concurrent imaging of synaptic vesicle recycling and calcium dynamics.

Frontiers in Molecular Neuroscience, 2011
Synaptic transmission involves the calcium-dependent release of neurotransmitter from synaptic vesicles. Genetically encoded optical probes emitting different wavelengths of fluorescent light in response to neuronal activity offer a powerful approach to
Haiyan eLi, Sarah M. Foss, Sarah M. Foss, Yuriy eDobryy, Yuriy eDobryy, C. Kevin ePark, Samuel Andrew Hires, Samuel Andrew Hires, Nathan C. Shaner, Nathan C. Shaner, Roger Y. Tsien, Leslie C. Osborne, Susan M. Voglmaier   +12 more
doaj   +1 more source

Synaptophysin and synaptoporin expression in the developing rat olfactory system [PDF]

, 1993
The expressions of two closely related synaptic vesicle antigens synaptophysin and synaptoporin were examined in the olfactory system of the adult rat and during pre- and postnatal development.
Traurig, H., Marquéze-Pouey, B., Betz, H., Grabs, D., Bergmann, M., Gratzl, Manfred, Schuster, Th., Mayerhofer, Artur   +7 more
core   +1 more source

Computational modeling of trans-synaptic nanocolumns, a modulator of synaptic transmission

Frontiers in Computational Neuroscience, 2022
Understanding synaptic transmission is of crucial importance in neuroscience. The spatial organization of receptors, vesicle release properties and neurotransmitter molecule diffusion can strongly influence features of synaptic currents. Newly discovered
Xiaoting Li, Xiaoting Li, Xiaoting Li, Gabriel Hémond, Antoine G. Godin, Antoine G. Godin, Nicolas Doyon, Nicolas Doyon   +7 more
doaj   +1 more source

Synaptic vesicle release regulates pre-myelinating oligodendrocyte-axon interactions in a neuron subtype-specific manner

Frontiers in Cellular Neuroscience
Oligodendrocyte-lineage cells are central nervous system (CNS) glia that perform multiple functions including the selective myelination of some but not all axons.
James R. Gronseth, Heather N. Nelson, Taylor L. Johnson, Taryn A. Mallon, Madeline R. Martell, Katrina A. Pfaffenbach, Bailey B. Duxbury, John T. Henke, Anthony J. Treichel, Jacob H. Hines   +9 more
doaj   +1 more source

Nonmuscle Myosin II helps regulate synaptic vesicle mobility at the Drosophila neuromuscular junction

BMC Neuroscience, 2010
Background Although the mechanistic details of the vesicle transport process from the cell body to the nerve terminal are well described, the mechanisms underlying vesicle traffic within nerve terminal boutons is relatively unknown.
Qiu Xinping, Seabrooke Sara, Stewart Bryan A   +2 more
doaj   +1 more source