Results 201 to 210 of about 549,591 (370)

Transient docking of synaptic vesicles: Implications and mechanisms. [PDF]

Curr Opin Neurobiol, 2022
Kusick GF, Ogunmowo TH, Watanabe S.
europepmc   +1 more source

The endophilin curvature-sensitive motif requires electrostatic guidance to recycle synaptic vesicles in vivo [PDF]

, 2021
Lin Zhang, Yu Wang, Yongming Dong, Aaradhya Pant, Yan Liu, Laura Masserman, Richard N. McLaughlin, Jihong Bai   +7 more
openalex   +1 more source

Molecular machines governing exocytosis of synaptic vesicles

Nature, 2012
R. Jahn, D. Fasshauer
semanticscholar   +1 more source

Hub genes and diagnostic model associated with mitochondrial function in Alzheimer's disease

Animal Models and Experimental Medicine, EarlyView.
Alzheimer's disease (AD) is the most common neurodegenerative disorder, and mitochondrial dysfunction has been confirmed in AD patients and mouse models. However, the pathogenic genes associated with AD and early diagnostic methods based on mitochondrial function remain to be explored.
Xuchao Zhu, Ling Zhang, Chuan Qin
wiley   +1 more source

Disease-associated mutations hyperactivate KIF1A motility and anterograde axonal transport of synaptic vesicle precursors [PDF]

, 2019
Kyoko Chiba, H. Takahashi, Min Chen, Hiroyuki Obinata, Shogo Arai, Koichi Hashimoto, Toshiyuki Oda, Richard J. McKenney, Shinsuke Niwa   +8 more
openalex   +1 more source

Merits and Limitations of Vesicle Pool Models in View of Heterogeneous Populations of Synaptic Vesicles

Neuron, 2015
E. Neher
semanticscholar   +1 more source

TARDBP (TDP‐43) Knock‐in Zebrafish Display a Late‐Onset Motor Phenotype and Loss of Large Spinal Cord Motor Neurons

Annals of Neurology, EarlyView.
Objective Mutations in TARDBP (encoding TDP‐43) are associated with the neurodegenerative disease amyotrophic lateral sclerosis (ALS) and include familial missense mutations where there are a lack of models and mechanisms examining how they are pathogenic.
Ziyaan A. Harji, Christian J. Rampal, Esteban C. Rodríguez, Virginie Petel Légaré, Alexandra Lissouba, Sabrina Semmler, Meijiang Liao, Jay P. Ross, Guy A. Rouleau, Christine Vande Velde, Gary A.B. Armstrong   +10 more
wiley   +1 more source

Synaptic Vesicle-bound Pyruvate Kinase can Support Vesicular Glutamate Uptake

, 2008
Atsuhiko Ishida, Yasuko Noda, Tetsufumi Ueda   +2 more
openalex   +1 more source

Resilience to Endoplasmic Reticulum Stress Mitigates Membrane Hyperexcitability Underlying Late Disease Onset in a Murine Model of SCA6

Annals of Neurology, EarlyView.
Objective An enduring puzzle in many inherited neurological disorders is the late onset of symptoms despite expression of function‐impairing mutant protein early in life. We examined the basis for onset of impairment in spinocerebellar ataxia type 6 (SCA6), a canonical late‐onset neurodegenerative ataxia which results from a polyglutamine expansion in ...
Haoran Huang, Taylor L. Charron, Min Fu, Miranda Dunn, Deborah M. Jones, Praveen Kumar, Satoshi Ishishita, Allan‐Hermann Pool, Ashwinikumar Kulkarni, Genevieve Konopka, Vikram G. Shakkottai   +10 more
wiley   +1 more source

CaV1 and CaV2 calcium channels mediate the release of distinct pools of synaptic vesicles. [PDF]

Elife, 2023
Mueller BD, Merrill SA, Watanabe S, Liu P, Niu L, Singh A, Maldonado-Catala P, Cherry A, Rich MS, Silva M, Maricq AV, Wang ZW, Jorgensen EM.   +12 more
europepmc   +1 more source