Results 211 to 220 of about 354,036 (296)

Intersectin-1 enhances calcium-dependent replenishment of the readily releasable pool of synaptic vesicles during development. [PDF]

J Physiol
Yang YM, Fekete A, Arsenault J, Sengar AS, Aitoubah J, Grande G, Li A, Salter EW, Wang A, Mark MD, Herlitze S, Egan SE, Salter MW, Wang LY.   +13 more
europepmc   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Overlapping role of synaptophysin and synaptogyrin family proteins in determining the small size of synaptic vesicles. [PDF]

Proc Natl Acad Sci U S A
Park D, Fujise K, Wu Y, Luján R, Del Olmo-Cabrera S, Wesseling JF, De Camilli P.   +6 more
europepmc   +1 more source

Tannic Acid Mitigates Monosodium Glutamate‐Induced Cortical Damage by Modulating Synaptic and Calcium‐Related Gene and Protein Expression

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neurotoxicity induced by excessive glutamatergic signaling is associated with synaptic dysfunction, calcium imbalance, and oxidative stress, which are key molecular events implicated in several neurodegenerative conditions. Monosodium glutamate (MSG), a common flavor enhancer, may exert neurotoxic effects, particularly on synaptic integrity ...
Medine Sibel Karagac, Enver Fehim Koçpinar, Hamid Ceylan   +2 more
wiley   +1 more source

Image Quality of 1.5 T MRI Using Dual‐Type Deep Learning Reconstruction for Pancreatic Cystic Lesions: An Exploratory Comparison With Conventional 3 T MRI Without Deep Learning Reconstruction

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Dual‐type deep learning reconstruction (DLR) may improve the pancreatic MRI image quality; however, the effects of different DLR strengths at 1.5 T compared with the conventional 1.5 T and 3 T MRI without DLR remain unclear. Purpose To evaluate the image quality of 1.5 T MRI reconstructed with different DLR strengths for pancreatic ...
Masaki Tsuda, Taiki Nozaki, Koji Sumi, Minobu Kamo, Ippei Ozaki, Fumio Morimura, Eugene Nishi, Yohsuke Suyama, Hiroaki Sugiura, Hiromi Edo   +9 more
wiley   +1 more source

5-Hydroxytryptophan artificial synaptic vesicles across the blood-brain barrier for the rapid-acting treatment of depressive disorder. [PDF]

Mater Today Bio
Chang P, Ma J, Li K, Wang W, Chen D, Liu Z, Zhan W, Zeng Y, Zhan Y.   +8 more
europepmc   +1 more source

miR‐9 Restricts Insulin Secretion by Targeting Rab34, Which Mediates Lysosomal Degradation of Proinsulin

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Insulin secretion is a complex, vesicular transport process. Rab34 is a key regulator of intracellular vesicle transport; however, its role in insulin secretion has not yet been reported. miRNA‐9 is vital for the development and progression of the diagnosis and treatment of type 2 diabetes. This study aimed to investigate whether miR‐9 targets
Zhen‐Zhen Guo, Ao‐Ying Li, Ting‐Ting Xiang, Zu‐Hao Zhang, Ao Deng, Yang Han   +5 more
wiley   +1 more source

Synaptotagmin 7 docks synaptic vesicles to support facilitation and Doc2α-triggered asynchronous release. [PDF]

Elife
Wu Z, Kusick GF, Berns MMM, Raychaudhuri S, Itoh K, Walter AM, Chapman ER, Watanabe S.   +7 more
europepmc   +1 more source

Novel Injectable Supports Long‐Term Recurrent Laryngeal Nerve and Partial Peripheral Nerve Repair

The Laryngoscope, EarlyView.
Following recurrent laryngeal nerve transection in C57BL/6 mice, intramuscular Agrin, neuregulin‐1, and acetylcholine treatment of the thyroarytenoid muscle supported functional reinnervation and preservation of neuromuscular structure at 84 days.
Aditya Bhatt, William Boswell, Elena Kennedy, Sunjay Anekal, Emma Mazurek, Ananya Tadikonda, Christopher Rafalko, Jasmine Strelow, Isaac Shipchandler, Patrick R. Finnegan, Stacey Halum   +10 more
wiley   +1 more source

Disruption of Dopamine Homeostasis Associated with Alteration of Proteins in Synaptic Vesicles: A Putative Central Mechanism of Parkinson's Disease Pathogenesis. [PDF]

Aging Dis
Jin X, Si X, Lei X, Liu H, Shao A, Li L.
europepmc   +1 more source