Results 191 to 200 of about 74,511 (302)

Paternal Exposure to the Neonicotinoid Pesticide Clothianidin Alters Sperm MicroRNA Profiles in Mice and Intergenerationally Reduces Locomotor Activity in Male Offspring

Journal of Applied Toxicology, EarlyView.
ABSTRACT Accumulating evidence suggests that paternal environmental factors have epigenetic effects on sperm and influence offspring. Neonicotinoid pesticides (NNs), which are widely used around the world, are known to affect offspring phenotypes through maternal exposure in mice, but the effect of the paternal exposure remains unknown.
Makiko Ito, Tetsushi Hirano, Sarika Nunobiki, Ayano Yoshimoto, Yukako Hara, Yuya Ishida, Sakura Yonoichi, Youhei Mantani, Toshifumi Yokoyama, Yoshiaki Tabuchi, Yoshinori Ikenaka, Nobuhiko Hoshi   +11 more
wiley   +1 more source

Endophilin A1 and synaptojanin 1-dependent endocytosis of synaptic vesicles in nociceptive spinal circuits maintains postoperative and cancer pain. [PDF]

Pain
Pessano Fialho MF, Thanigai Arasu GS, Chen S, Imlach WL, Bunnett NW, Tonello R.   +5 more
europepmc   +1 more source

High-Precision Mapping of Membrane Proteins on Synaptic Vesicles using Spectrally Encoded Super-Resolution Imaging. [PDF]

Angew Chem Int Ed Engl, 2023
Jiang Y, Zhang J, Jung SR, Chen H, Xu S, Chiu DT.   +5 more
europepmc   +1 more source

Tannic Acid Mitigates Monosodium Glutamate‐Induced Cortical Damage by Modulating Synaptic and Calcium‐Related Gene and Protein Expression

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neurotoxicity induced by excessive glutamatergic signaling is associated with synaptic dysfunction, calcium imbalance, and oxidative stress, which are key molecular events implicated in several neurodegenerative conditions. Monosodium glutamate (MSG), a common flavor enhancer, may exert neurotoxic effects, particularly on synaptic integrity ...
Medine Sibel Karagac, Enver Fehim Koçpinar, Hamid Ceylan   +2 more
wiley   +1 more source

SV2B defines a subpopulation of synaptic vesicles. [PDF]

J Mol Cell Biol
Paulussen I, Beckert H, Musial TF, Gschossmann LJ, Wolf J, Schmitt M, Clasadonte J, Mairet-Coello G, Wolff C, Schoch S, Dietrich D.   +10 more
europepmc   +1 more source

Automated Detection and Localization of Synaptic Vesicles in Electron Microscopy Images. [PDF]

eNeuro, 2022
Imbrosci B, Schmitz D, Orlando M.
europepmc   +1 more source

Alpha‐Synuclein Promotes Anterograde Vesicle Transport in Melanocytes and Melanoma Cells: A Pro‐Survival Function

Journal of the Chinese Chemical Society, EarlyView.
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley   +1 more source

Harnessing Dye-Induced Local Heating in Lipid Membranes: A Path to Near-Infrared Light-Modulated Artificial Synaptic Vesicles. [PDF]

ACS Nano
Sarker SR, Yamazaki T, Sou K, Takemura I, Kurita Y, Nomura K, Ichimura M, Suzuki T, Kai A, Araki T, Hattori S, Furuyama T, Chang YT, Kiya T, Arai S.   +14 more
europepmc   +1 more source

A parametric electrophysiological–transcriptomic map of MscL‐G22S sonogenetic neuromodulation in the rat hippocampus: Toward precision ultrasound neuromodulation

Journal of Intelligent Medicine, EarlyView.
Using a factorial sweep of ultrasound fundamental and pulse repetition frequencies, we built a parametric electrophysiological–transcriptomic map of MscL‐G22S‐mediated hippocampal neuromodulation, providing reference data for precision, parameter‐aware ultrasound neuromodulation.
Xin Li, Bozhan Wang, Chenguang Zheng, Yutao Tian   +3 more
wiley   +1 more source

Number and relative abundance of synaptic vesicles in functionally distinct priming states determine synaptic strength and short-term plasticity. [PDF]

J Physiol
Lin KH, Ranjan M, Lipstein N, Brose N, Neher E, Taschenberger H.   +5 more
europepmc   +1 more source