PLoS Genetics, 2020 Meiotic recombination is essential for faithful segregation of homologous chromosomes during gametogenesis. The progression of recombination is associated with dynamic changes in meiotic chromatin structures.
Kazumasa Takemoto +6 more
doaj +1 more source
A BIRD´S-EYE VIEW OF CHROMOSOMES DURING MEIOTIC PROPHASE I [PDF]
BAG. Journal of Basic and Applied Genetics, 2022 The present review aims to summarize the research carried out in relation to meiosis in birds, especially by observing the protein axes of the chromosomes in prophase I of meiosis. This line of research, initially developed in Argentina, has provided key
Pigozzi M.I.
doaj +1 more source
Principles of meiotic chromosome assembly revealed in S. cerevisiae [PDF]
, 2019 During meiotic prophase, chromosomes organise into a series of chromatin loops emanating from a proteinaceous axis, but the mechanisms of assembly remain unclear.
A Goloborodko +69 more
core +2 more sources
Essential and checkpoint functions of budding yeast ATM and ATR during meiotic prophase are facilitated by differential phosphorylation of a meiotic adaptor protein, Hop1 [PDF]
, 2015 A hallmark of the conserved ATM/ATR signalling is its ability to mediate a wide range of functions utilizing only a limited number of adaptors and effector kinases.
A Alcasabas +51 more
core +11 more sources
Evidence that MEK1 positively promotes interhomologue double-strand break repair [PDF]
, 2010 During meiosis there is an imperative to create sufficient crossovers for homologue segregation. This can be achieved during repair of programmed DNA double-strand breaks (DSBs), which are biased towards using a homologue rather than sister chromatid as ...
Bishop-Bailey, A +5 more
core +1 more source
Meiotic sex chromosome cohesion and autosomal synapsis are supported by Esco2.
, 2020 In mitotic cells, establishment of sister chromatid cohesion requires acetylation of the cohesin subunit SMC3 (acSMC3) by ESCO1 and/or ESCO2. Meiotic cohesin plays additional but poorly understood roles in the formation of chromosome axial elements (AEs)
Biswas, U. +6 more
core +1 more source
Synaptonemal Complexities and Commonalities [PDF]
Molecular Cell, 2003 Formation of synaptonemal complex and high levels of homologous recombination are the hallmarks of meiotic prophase. The relationship between these two processes has been the subject of intense study for nearly 50 years. Recent findings highlight the differences and commonalities of this relationship in different species.
openaire +2 more sources
Crystal structure of Hop2-Mnd1 and mechanistic insights into its role in meiotic recombination [PDF]
, 2015 In meiotic DNA recombination, the Hop2-Mnd1 complex promotes Dmc1-mediated single-stranded DNA (ssDNA) invasion into homologous chromosomes to form a synaptic complex by a yet-unclear mechanism.
Alexandra-Styliani Kalantzi +66 more
core +3 more sources
Human disease locus discovery and mapping to molecular pathways through phylogenetic profiling
Molecular Systems Biology, 2013 Genes with common profiles of the presence and absence in disparate genomes tend to function in the same pathway. By mapping all human genes into about 1000 clusters of genes with similar patterns of conservation across eukaryotic phylogeny, we ...
Yuval Tabach +9 more
doaj +1 more source
Ultrastructural analysis of chromatin in meiosis I plus II of rye (Secale cereale L.) [PDF]
, 2004 Scanning electron microscopy (SEM) proves to be an appropriate technique for imaging chromatin organization in meiosis I and II of rye (Secale cereale) down to a resolution of a few nanometers.
Herrmann, Reinhold G. +3 more
core +1 more source