The synaptonemal complex aligns meiotic chromosomes by wetting. [PDF]
Sci AdvGordon SG +5 more
europepmc +2 more sources
Meiotic Chromosome Structure, the Synaptonemal Complex, and Infertility.
Annual review of genomics and human genetics (Print), 2023 In meiosis, homologous chromosome synapsis is mediated by a supramolecular protein structure, the synaptonemal complex (SC), that assembles between homologous chromosome axes.
I. Adams, O. Davies
semanticscholar +1 more source
PLK1 depletion alters homologous recombination and synaptonemal complex disassembly events during mammalian spermatogenesis. [PDF]
Mol Biol Cell, 2022 Wellard SR +4 more
europepmc +3 more sources
Cytological analysis of MRE11 protein during early meiotic prophase I in Arabidopsis and tomato [PDF]
, 2008 Early recombination nodules (ENs) are multiprotein complexes that are thought to be involved in synapsis and recombination, but little is known about their components or how they may be involved in these events. In this study, we describe the cytological
Anderson, L.K. +6 more
core +13 more sources
The Plant Cell, 2021 Meiosis is a specialized cell division that gives rise to genetically distinct gametic cells. Meiosis relies on the tightly controlled formation of DNA double-strand breaks (DSBs) and their repair via homologous recombination for correct chromosome ...
Marie-Therese Kurzbauer +8 more
semanticscholar +1 more source
Meiosis in mice without a synaptonemal complex. [PDF]
PLoS ONE, 2011 The synaptonemal complex (SC) promotes fusion of the homologous chromosomes (synapsis) and crossover recombination events during meiosis. The SC displays an extensive structural conservation between species; however, a few organisms lack SC and execute ...
Anna Kouznetsova +3 more
doaj +1 more source
Involvement of synaptonemal complex proteins in sex chromosome segregation during marsupial male meiosis. [PDF]
PLoS Genetics, 2006 Marsupial sex chromosomes break the rule that recombination during first meiotic prophase is necessary to ensure reductional segregation during first meiotic division.
Jesús Page +9 more
doaj +1 more source
Synaptonemal complex components persist at centromeres and are required for homologous centromere pairing in mouse spermatocytes. [PDF]
PLoS Genetics, 2012 Recent studies in simple model organisms have shown that centromere pairing is important for ensuring high-fidelity meiotic chromosome segregation. However, this process and the mechanisms regulating it in higher eukaryotes are unknown.
C Gaston Bisig +6 more
doaj +1 more source
Heterogeneity in conservation of multifunctional partner enzymes with meiotic importance, CDK2 kinase and BRCA1 ubiquitin ligase [PDF]
PeerJ, 2021 The evolution of proteins can be accompanied by changes not only to their amino acid sequences, but also their structural and spatial molecular organization.
Sergey Matveevsky, Tatiana Grishaeva
doaj +2 more sources
Crystal Structure of C-Terminal Coiled-Coil Domain of SYCP1 Reveals Non-Canonical Anti-Parallel Dimeric Structure of Transverse Filament at the Synaptonemal Complex. [PDF]
PLoS ONE, 2016 The synaptonemal complex protein 1 (SYCP1) is the main structural element of transverse filaments (TFs) of the synaptonemal complex (SC), which is a meiosis-specific complex structure formed at the synapse of homologue chromosomes to hold them together ...
Eun Kyung Seo +4 more
doaj +1 more source