Results 211 to 220 of about 29,778 (263)

Thirty years of synaptosome research

Journal of Neurocytology, 1993
Detached synapses (synaptosomes), first isolated by the author in 1958 and identified as such in 1960, are sealed presynaptic nerve terminals often with a portion of the target cell--sometimes amounting to a complete dendritic spine--adhering to their external surface.
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A new selective inhibitor for uptake of serotonin into synaptosomes of rat brain: 3-(p-trifluoromethylphenoxy). N-methyl-3-phenylpropylamine.

Journal of Pharmacology and Experimental Therapeutics, 1975
3-(p-Trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine (Lilly 110140) competitively inhibited the uptake of serotonin (5-HT), norepinephrine (NE) and dopamine into synaptosomes of rat brain with Ki values of 5.5 x 10-minus8, 9.5 x 10-minus6 and 1.3 x ...
D. Wong, F. Bymaster, J. Horng, B. Molloy   +3 more
semanticscholar   +1 more source

Phosphatidate Metabolism in Stimulated Synaptosomes

Biochemical Society Transactions, 1977
Acetylcholine increases the incorporation of 32P1 into phosphatidate of guinea-pig brain synaptosomes incubated in vitro (Durell & Sodd, 1966; Schacht & Agranoff, 1972; Yagihara & Hawthorne, 1972). Three pathways for the synthesis of phosphatidate operate in brain tissue: acylation of glycerol 3-phosphate, acylation of dihydroxyacetone phosphate ...
J N, Hawthorne, M R, Pickard
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CATION MODULATION OF SYNAPTOSOMAL RESPIRATION

Journal of Neurochemistry, 1972
Abstract— Synaptosomes were prepared from the cerebral cortex of the adult rat by a rapid technique, involving the use of centrifugation in a Ficoll‐sucrose discontinuous gradient. Adequate respiratory control ratios were obtained with glutamate and succinate plus rotenone.
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Deregulated Local Protein Synthesis in the Brain Synaptosomes of a Mouse Model for Alzheimer’s Disease

Molecular Neurobiology, 2019
C. Cefaliello, E. Penna, C. Barbato, Giuseppina Di Ruberto, M. Mollica, G. Trinchese, L. Cigliano, T. Borsello, J. Chun, A. Giuditta, C. Perrone-Capano, M. C. Miniaci, M. Crispino   +12 more
semanticscholar   +1 more source

From the synaptosome to the intact brain

Biochemical Society Transactions, 1994
Introduction Ikain function is centered at the synapse and, consequently, substantial scientific efforts have been directed towards exploring synaptic function. In neurochemical research, it has been customary to divide neuronal parts of the synapse into two. Since the early 1960s.
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Upregulation of presynaptic proteins and protein kinases associated with enhanced glutamate release from axonal terminals (synaptosomes) of the medial prefrontal cortex in rats with neuropathic pain

Pain, 2014
K. Hung, Su-Jane Wang, Ying-Chou Wang, T. Chiang, Chia-Chuan Wang   +4 more
semanticscholar   +1 more source

Synaptosomes secrete and uptake functionally active microRNAs via exocytosis and endocytosis pathways

Journal of Neurochemistry, 2013
Jie Xu, Qun Chen, Ke Zen, Chenyu Zhang, Qipeng Zhang   +4 more
semanticscholar   +1 more source

A rapid Percoll gradient procedure for preparation of synaptosomes

Nature Protocols, 2008
P. Dunkley, P. Jarvie, P. Robinson
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Studies on protective mechanisms of four components of green tea polyphenols against lipid peroxidation in synaptosomes.

Biochimica et Biophysica Acta, 1996
Qiong Guo, Baolu Zhao, Meifen Li, S. Shen, Wenjuan Xin   +4 more
semanticscholar   +1 more source