Results 201 to 210 of about 29,778 (263)

FLUID SPACES OF SYNAPTOSOME BEDS

Journal of Neurochemistry, 1974
Abstract—The fluid spaces of synaptosome beds were estimated by vol. measurement and also by a combination of chemical and enzymic analyses. The extra‐synaptosomal space of the beds was concluded to be about 80 per cent of their total vol. Beds prepared by conventional techniques after sucrose density‐gradient centrifugation were found to contain 0‐08 ...
G M, Heaton, H S, Bachelard
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SYNAPTOSOMAL PHOSPHORYLATION OF D‐GLUCOSAMINE

Journal of Neurochemistry, 1978
Abstract— Synaptosomal fractions from rat brains can phosphorylate d‐glucosamine once it is transported across the synaptosomal membrane. Intrasynaptosomal phosphorylation of d‐glucosamine was rapid; up to 80% of the d‐glucosamine was recovered as the phosphorylated amino sugar during 15 min of incubation with the substrate.
C H, Tan, E, Raghupathy, N A, Peterson
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Synaptosomal transport and acetylation of choline

Life Sciences, 1977
Abstract Acetylcholine (ACh) synthesis can be impaired by reduction of the availability of either of its precursors, choline (Ch) or acetylcoenzyme A (AcCoA). The high affinity transport of Ch is inhibited by hemicholinium-3 and this results in reduced synthesis of ACh (1–3). Under some circumstances ACh metabolism in the brain appears to be affected
R S, Jope, D J, Jenden
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Ethanol and synaptosomal calcium homeostasis

Biochemical Pharmacology, 1990
The effect of ethanol on synaptosomal calcium homeostasis was studied in the rat using the fluorescent dye, fura-2, and 45Ca uptake. The mitochondrial poison, cyanide, caused a substantial rise in intracellular free Ca2+ concentration, [Ca2+]i, over that of control synaptosomes. This rise was enhanced by ethanol. Ethanol also augmented the rise in [Ca2+
Davidson, Mark, Wilce, Peter, Shanley, Brian   +2 more
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Antigenicity of isolated synaptosomal membranes

Experimental Neurology, 1974
Abstract An antiserum has been prepared against an isolated synaptosomal membrane preparation obtained from chick forebrain. Immunohistochemical localization studies showed that the antiserum reacts with nerve terminal membranes and preterminal axonal membranes in the central nervous system.
B G, Livett, J A, Rostas, P L, Jeffrey, L, Austin   +3 more
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Effects of ammonia on synaptosomal membranes

Biochemical and Biophysical Research Communications, 1984
Acute and sustained hyperammonemia in mice resulted in a decrease of the transition temperature of Arrhenium plots of synaptosomal (Na+-K+)ATPase. The activation energies in both phases of the plots were increased. "In vitro" addition of ammonia produced similar changes. This seems to indicate that ammonia alters the physical properties of synaptosomal
J E, O'Connor, C, Guerri, S, Grisolía
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Protein Methylation in Cerebellar Synaptosomes

Journal of Neurochemistry, 1993
Abstract: Synaptosomes from five regions of adult rat brain were isolated, analyzed for methyl acceptor proteins, and probed for methyltransferases by photoaffinity labeling. Methylated proteins of 17 and 35 kDa were observed in all regions, but cerebellar synaptosomes were enriched in a 21–26‐kDa family of methyl acceptor proteins and contained a ...
L S, Wright, F L, Siegel
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Glycolytic enzyme levels in synaptosomes

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1985
The specific activities of glucosephosphate isomerase, aldolase, triosephosphate isomerase, glyceraldehydephosphate dehydrogenase, phosphoglycerate kinase, phosphoglycerate mutase, pyruvate kinase and lactate dehydrogenase were all higher in the synaptoplasmic fraction from rat brain than in 100,000 g supernatant fraction of rat brain homogenates when ...
H R, Knull, S J, Fillmore
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Brevetoxins, unique activators of voltage-sensitive sodium channels, bind to specific sites in rat brain synaptosomes.

Molecular Pharmacology, 1986
The polyether lipid-soluble toxins isolated from the marine dinoflagellate Ptychodiscus brevis (formerly Gymnodinium breve) have been determined to bind to a unique site associated with rat brain synaptosomes.
M. Poli, T. Mende, D. Baden
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The structure of synaptosomal plasma membrane

Drug and Alcohol Dependence, 1979
Synaptosomal plasma membrane (SPM), like other plasma membranes, is composed of lipids and proteins and appears to conform to the "fluid mosaic" model proposed by Singer and Nicolson. SPM components show a marked asymmetry with respect to their inside-outside distribution, with the majority of proteins being external.
A P, Smith, H H, Loh
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