Results 81 to 90 of about 16,154 (215)

Synergistic immunomodulatory effect of synbiotics pre- and postoperative resection of pancreatic ductal adenocarcinoma: a randomized controlled study

Cancer Immunology and Immunotherapy
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a highly immunosuppressive microenvironment. This single-blind, randomized study aimed to evaluate the synergistic immunomodulatory effects of synbiotics (probiotics and inulin ...
Sara Maher, Hesham A. Elmeligy, T. Aboushousha, N. Helal, Yousra Ossama, Mahmoud Rady, A. Hassan, Manal Kamel   +7 more
semanticscholar   +1 more source

The impact of prebiotics, probiotics and synbiotics on the prevention and treatment of atopic dermatitis in children: an umbrella meta-analysis

Frontiers in Pediatrics
BackgroundStudies have suggested that the administration of prebiotics, probiotics and synbiotics (pre-, pro-, and synbiotics) may potentially decrease the incidence of atopic dermatitis (AD) and alleviate its severity in children; however, recent ...
Lifeng Wang, Lijuan Xu
doaj   +1 more source

The Double‐Edged Sword of Gestational Insulin Resistance: Navigating Maternal Adaptation and Its Risks for Pregnancy and Offspring Health

Obesity Reviews, EarlyView.
ABSTRACT Although much research focuses on the effects of hyperglycemia during pregnancy on maternal and offspring health, this narrative review specifically centers on the role of insulin resistance (IR) in pregnancy complications and offspring long‐term health.
Runyu Du, Fei Wang, Ling Li, Qiuyue Wang
wiley   +1 more source

Psychobiotics and the microbiota–gut–brain axis: Emerging paradigms in mental health modulation

Experimental Physiology, EarlyView.
Abstract The global rise in mental health conditions has prompted interest in interventions that act beyond conventional psychopharmacology. Psychobiotics, broadly understood as live microorganisms or microbe‐derived products that interact with the microbiota–gut–brain axis, have been suggested to exert neuroactive effects through neural, immune ...
Amir Arsalan Ghahari, Mehrdad Nourizadeh, Mehrdad SalekShahabi, Shaghayegh Davari, Saeid Mohammadzadeh Mounesyar   +4 more
wiley   +1 more source

The Influence of the Gut Microbiome on Obesity in Adults and the Role of Probiotics, Prebiotics, and Synbiotics for Weight Loss

Preventive Nutrition and Food Science, 2020
The link between the gut microbiome and obesity is not well defined. Understanding of the role of the gut microbiome in weight and health management may lead to future revolutionary changes for treating obesity.
A. Aoun, F. Darwish, Natacha Hamod
semanticscholar   +1 more source

Probiotics, Prebiotics, and Synbiotics

Journal of Pediatric Surgical Nursing, 2017
Probiotics are living microorganisms which, when ingested in certain amounts, have a positive impact on human health, mainly due to their roles in improving the balance of the intestinal microflora. On the other hand, the prebiotic are food ingredients that may also have a positive impact in the improvement of the intestinal flora.
Guiné, Raquel, Silva, A. C. F.
openaire   +3 more sources

Effects of Prebiotics, Probiotics, and Synbiotics on the Bodyweight, Blood Glucose, Triglyceride and TNF-α of Diet-induced Obesity Rats

Qanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya, 2020
High-fat diet leads to obesity-associated chronic low-grade inflammation. Prebiotics, probiotics, and synbiotics produced short-chain fatty acids (SCFA), bonded to G protein-coupled receptors (GPR)-41 and GPR-43 decreased triglyceride deposits in ...
Lenny Octavia, Soebagijo Adi Soelistijo, Agung Dwi Wahyu Widodo   +2 more
doaj   +1 more source

The Gut‐Liver Axis in Metabolic Dysfunction‐Associated Steatotic Liver Disease: From Mechanistic Insights to Precision Therapeutics

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Description: This review synthesizes groundbreaking advances in the gut‐liver axis for MASLD management. It details mechanistic pathways from transkingdom dysbiosis to liver pathology, integrating AI‐driven diagnostics and host genetics (PNPLA3). The framework transitions from broad microbial restoration to precision medicine, showcasing targeted ...
Shaoliang Zhu, Mengjie Zou, Qijun Wu, Yan Zou, Tingting Tan, Zhangnan Huang, Zheng Gong, Honglin Luo, Xiaofeng Dong   +8 more
wiley   +1 more source

Fermented Lacticaseibacillus Paracasei Cultures Ameliorate Colitis by Modulating Microbiota‐Derived Tryptophan Metabolism and Macrophage Polarization

Advanced Science, Volume 13, Issue 13, 3 March 2026.
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang, Jingzhou Sun, Xin Zheng, Huiqing Yang, Aowen Xie, Yuxuan Ding, Yuxia Mei, Jinshan Li, Yuanliang Hu, Min Ren, Yangyang Liu, Yunxiang Liang   +11 more
wiley   +1 more source

Obesity and Natural Products: Mechanisms, Therapeutic Potential, and Future Directions

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
Natural products such as EGCG, berberine, curcumin, and capsaicin modulate key metabolic pathways including AMPK activation, adipogenesis inhibition, and inflammatory signaling. While clinical trials demonstrate modest benefits on body weight and metabolic parameters, translational challenges related to bioavailability, dose feasibility, and regulatory
Ohoud M. Marie, Abdelghafar Abu‐Elsaoud   +1 more
wiley   +1 more source