Results 81 to 90 of about 169,807 (345)

Inhibition of Candida albicans biofilm by lipopeptide AC7 coated medical-grade silicone in combination with farnesol

AIMS Bioengineering, 2018
Biosurfactants affect interaction of microorganisms with material surfaces by altering interfacial properties, and have recently attract the attention of the scientific community for their use as anti-adhesive and anti-biofilm agents.
Chiara Ceresa, Francesco Tessarolo, Devid Maniglio, Iole Caola, Giandomenico Nollo, Maurizio Rinaldi, Letizia Fracchia   +6 more
doaj   +1 more source

Mediterranean diet adherence and synergy with acute myocardial infarction and its determinants. a multicenter case-control study in Italy. [PDF]

, 2018
Cardiovascular diseases are the leading causes of mortality and morbidity in Western countries. The possible synergistic effect of poor adherence to a Mediterranean diet (MD) and other risk factors for acute myocardial infarction (AMI) such as ...
Agati, L, Barillà, F, Colamesta, V, Di Murro, F, Ferrante, F, Firenze, A, La Torre, G, Mannocci, A, Maurici, M, Saulle, R, Siliquini, R   +10 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Synergistic Effects of Nucleating Agents and Plasticizers on the Crystallization Behavior of Poly(lactic acid)

Molecules, 2015
The synergistic effect of nucleating agents and plasticizers on the thermal and mechanical performance of PLA nanocomposites was investigated with the objective of increasing the crystallinity and balancing the stiffness and toughness of PLA mechanical ...
Xuetao Shi, Guangcheng Zhang, Thanh Vu Phuong, Andrea Lazzeri   +3 more
doaj   +1 more source

Quantitative functional interrelations within the cis-regulatory system of the S. purpuratus Endo16 gene [PDF]

, 1996
Embryonic expression of the Endo16 gene of Strongylocentrotus purpuratus is controlled by interactions with at least 13 different DNA-binding factors. These interactions occur within a cis-regulatory domain that extends about 2300 bp upstream from the ...
Davidson, Eric H., Moore, James G., Yuh, Chiou-Hwa   +2 more
core  

Evaluation of Three Trap Types and Five Lures for Monitoring \u3ci\u3eHylurgus Ligniperda\u3c/i\u3e (Coleoptera: Scolytidae) and Other Local Scolytids in New York [PDF]

, 2018
Hylurgus ligniperda (Coleoptera: Scolytidae) is a pine (Pinus spp.) pest native to Eurasia and northern Africa. In December 2000, an established population of H. ligniperda was discovered in Monroe County, New York.
Haack, Robert A, Petrice, Toby R, Poland, Therese M   +2 more
core   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Mapping erosion-corrosion of carbon steel in oil-water solutions : Effect of velocity and applied potential [PDF]

, 2012
In this study, the combined effects of erosion and corrosion on carbon steel were investigated in three environments containing crude oil, reservoir water, and a mixture of both solutions at a range of applied potentials, velocities and impact angle. The
Abdulrahman, Ghaith, Stack, Margaret
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source