Results 21 to 30 of about 74,456 (251)
How synonymous mutations alter enzyme structure and function over long timescales
bioRxiv, 2021 Enzymes with identical sequences of amino acids can display varying activities when encoded with mRNA with different properties, but why this is the case has been a mystery.
Yang Jiang +8 more
semanticscholar +1 more source
BMC Ecology and Evolution, 2021 Background Synonymous mutations do not alter the amino acids and therefore are regarded as neutral for a long time. However, they do change the tRNA adaptation index (tAI) of a particular codon (independent of its context), affecting the tRNA ...
Duan Chu, Lai Wei
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Mutation rates and selection on synonymous mutations in SARS-CoV-2
bioRxiv, 2021 The COVID-19 pandemic has seen an unprecedented response from the sequencing community. Leveraging the sequence data from more than 140,000 SARS-CoV-2 genomes, we study mutation rates and selective pressures affecting the virus.
N. de Maio +5 more
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ANALISIS PERBEDAAN VERBA AMARU DAN NOKORU
Izumi, 2017 Japanese has specific vocabulary. Unlike Indonesian language that has more general vocabulary. When translated into Indonesian, there are several Japanese word that have the same or synonymous meaning.
Elizabeth Ika Hesti Nindya
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A minimal role for synonymous variation in human disease
bioRxiv, 2022 Synonymous mutations change the DNA sequence of a gene without affecting the amino acid sequence of the encoded protein. Although emerging evidence suggests that synonymous mutations can impact RNA splicing, translational efficiency, and mRNA stability1,
R. Dhindsa +9 more
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When a Synonymous Variant Is Nonsynonymous
Genes, 2022 Term synonymous variation is widely used, but frequently in a wrong or misleading meaning and context. Twenty three point eight % of possible nucleotide substitution types in the universal genetic code are for synonymous amino acid changes, but when ...
M. Vihinen
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The Canadian Entomologist, 1902 In 1834 Dejean proposed the name Euchætes for a genus of Coleoptera, and it had thus been preoccupied for seven years when Harris used it in 1841 for the moth named by Drury, Bombyx Egle.In 1858 it was used for a third time by Sclater for a genus of birds, and in 1876 Leconte described another genus of Coleoptera under this same much-used name.As it is
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Fitness costs of synonymous mutations in the rpsT gene can be compensated by restoring mRNA base pairing. [PDF]
PLoS ONE, 2013 We previously reported that the distribution of fitness effects for non-synonymous and synonymous mutations in Salmonella typhimurium ribosomal proteins S20 and L1 are similar, suggesting that fitness constraints are present at the level of mRNA. Here we
Peter A Lind, Dan I Andersson
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Synonymous mutations reveal genome-wide levels of positive selection in healthy tissues
Nature Genetics, 2021 Genetic alterations under positive selection in healthy tissues have implications for cancer risk. However, total levels of positive selection across the genome remain unknown.
Gladys Y. P. Poon +3 more
semanticscholar +1 more source
Appropriation, Gentrification, Colonisation: Newly Synonymous?
Lexis: Journal in English Lexicology, 2020 Appropriation, gentrification, and colonisation originated as precise technical terms. This study analyses examples of each word in recent mainstream online news texts, and demonstrates that all three have undergone semantic change, particularly ...
Seth W. Mehl
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