Results 11 to 20 of about 220,441 (262)
Are synonymous codons indeed synonymous?
Biomolecular Concepts, 2012 It has long been known that the distribution and frequency of occurence of synonymous codons can vary greatly among different species, and that the abundance of isoaccepting tRNA species could also be very different.
Venetianer Pál
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A multispecies approach for comparing sequence evolution of X-linked and autosomal sites in Drosophila [PDF]
, 2008 Population genetics models show that, under certain conditions, the X chromosome is expected to be under more efficient selection than the autosomes.
Vicoso, Beatriz +2 more
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Bayesian Estimation of Nonsynonymous/Synonymous Rate Ratios for Pairwise Sequence Comparisons [PDF]
, 2014 The nonsynonymous/synonymous rate ratio (ω = dN/dS) is an important measure of the mode and strength of natural selection acting on nonsynonymous mutations in protein-coding genes. The simplest such analysis is the estimation of the dN/dS ratio using two
dos Reis, M, Yang, Z, Angelis, K
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Synonymous substitution rates predict HIV disease progression as a result of underlying replication dynamics [PDF]
, 2007 Upon HIV transmission, some patients develop AIDS in only a few months, while others remain disease free for 20 or more years. This variation in the rate of disease progression is poorly understood and has been attributed to host genetics, host immune ...
Pybus, OG +37 more
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Distribution of synonymous and non-synonymous changes in VP1.
, 2022 A) The distribution of synonymous and non-synonymous changes in VP1 shows that most sites have between 5–10 synonymous changes, but 0 or 1 non-synonymous change, suggesting most of protein is under purifying selection.
Emma B. Hodcroft (10204670) +13 more
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Гуманитарные и юридические исследования, 2021 The article deals with the feature of prose by M. I. Tsvetaeva, based on the system of defining. The author defines such concepts as denotation, signified contextual metadefinition and relative definition.
O. S. Gavrilova
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Somatic synonymous mutations in regulatory elements contribute to the genetic aetiology of melanoma
BMC Medical Genomics, 2020 Background Non-synonymous mutations altering tumor suppressor genes and oncogenes are widely studied. However, synonymous mutations, which do not alter the protein sequence, are rarely investigated in melanoma genome studies. Methods We explored the role
Di Zhang, Junfeng Xia
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OENO One, 1990 Ce travail présente des caractéristiques agronomiques de 211 variétés de Vitis vinifera L. étudiées en Espagne pendant 25 ans: production de raisin, teneur en sucre des moûts et poids des bois de taille.
Luis Hidalgo Fernández-Cano
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BMC Bioinformatics, 2023 Background Synonymous mutations, which change the DNA sequence but not the encoded protein sequence, can affect protein structure and function, mRNA maturation, and mRNA half-lives.
Yiyun Rao +3 more
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Codon usage bias controls mRNA and protein abundance in trypanosomatids
eLife, 2018 Protein abundance differs from a few to millions of copies per cell. Trypanosoma brucei presents an excellent model for studies on codon bias and differential gene expression because transcription is broadly unregulated and uniform across the genome.
Laura Jeacock, Joana Faria, David Horn
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