Results 41 to 50 of about 74,456 (251)

Synonymous Codon Usage Controls Various Molecular Aspects [PDF]

open access: yesGenomics & Informatics, 2017
Synonymous sites are generally considered to be functionally neutral. However, there are recent contradictory findings suggesting that synonymous alleles might have functional roles in various molecular aspects.
Eu-Hyun Im, Sun Shim Choi
doaj   +1 more source

SECOND LANGUAGE ACQUISITION IN THE CLASSROOM

open access: yesInternational Studies Journal, 2022
This paper examines the acquisition of Second Language in the classroom. The paper cites the ongoing increase of second language research and encourages educators to apply the more relevant research to their classroom methodology.
IDEGU A. SOLOMON
doaj  

Synonymous nucleotide changes drive papillomavirus evolution

open access: yesTumour Virus Research, 2022
Papillomaviruses have been evolving alongside their hosts for at least 450 million years. This review will discuss some of the insights gained into the evolution of this diverse family of viruses.
Kelly M. King   +3 more
doaj   +1 more source

Decoding the effects of synonymous variants

open access: yesbioRxiv, 2021
Synonymous single nucleotide variants (sSNVs) are common in the human genome but are often overlooked. However, sSNVs can have significant biological impact and may lead to disease. Existing computational methods for evaluating the effect of sSNVs suffer
Zishuo Zeng, A. Aptekmann, Y. Bromberg
semanticscholar   +1 more source

Molecular bases for strong phenotypic effects of single synonymous codon substitutions in the E. coli ccdB toxin gene

open access: yesBMC Genomics, 2023
Background Single synonymous codon mutations typically have only minor or no effects on gene function. Here, we estimate the effects on cell growth of ~ 200 single synonymous codon mutations in an operonic context by mutating almost all positions of ccdB,
Priyanka Bajaj   +2 more
doaj   +1 more source

Dissimilation of synonymous codon usage bias in virus-host coevolution due to translational selection

open access: yesNature Ecology & Evolution, 2020
Eighteen of the 20 amino acids are each encoded by more than one synonymous codon. Due to differential transfer RNA supply within the cell, synonymous codons are not used with equal frequency, a phenomenon termed codon usage bias (CUB).
Feng Chen   +8 more
semanticscholar   +1 more source

Synonymous genes explore different evolutionary landscapes. [PDF]

open access: yesPLoS Genetics, 2008
The evolutionary potential of a gene is constrained not only by the amino acid sequence of its product, but by its DNA sequence as well. The topology of the genetic code is such that half of the amino acids exhibit synonymous codons that can reach ...
Guillaume Cambray, Didier Mazel
doaj   +1 more source

Synonymous mutations and the molecular evolution of SARS-CoV-2 origins

open access: yesbioRxiv, 2020
Human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is most closely related, by average genetic distance, to two coronaviruses isolated from bats, RaTG13 and RmYN02.
Hongru Wang, L. Pipes, R. Nielsen
semanticscholar   +1 more source

Identification and Characterization of the COBRA-Like Gene Family in the Spinacia oleracea L. Genome

open access: yesTürkiye Tarımsal Araştırmalar Dergisi
COBL genes play an important role in the biosynthesis of cellulose, the main component of the cell wall. This study aimed to identify and characterize members of the COBL gene family that have not been characterized in the spinach genome.
Ayşe Gül Kasapoğlu
doaj   +1 more source

SNPs in coat colour genes in goats

open access: yesItalian Journal of Animal Science, 2010
Coat colour genes are useful candidates for breeds traceability of farm animals. To identify SNPs in genes involved in pigmentation in goat, we carried out in silico studies in human, mouse and cattle.We analysed 41 genes and we found: 88 SNPs in mouse ...
L. Nicoloso, P. Crepaldi
doaj   +1 more source

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