Results 121 to 130 of about 660,576 (241)

IDENTIFICATION OF DISEASE GENES FOR RARE AUTOSOMAL RECESSIVE EPILEPTIC SYNDROMES BY HOMOZYGOSITY MAPPING [PDF]

open access: yes, 2011
Introduction: The genetics of the most common neurological disorders, including epilepsy, with mendelian inheritance has been dissected in the last twenty years. However the genetic etiology of some rare epileptic conditions is still unknown.
Coppola, Antonietta
core  

Determining frequencies of fungicide resistance in Leptosphaeria maculans that render demethylation inhibitor fungicides ineffective in the field

open access: yesPest Management Science, EarlyView.
As little as 1–10% of the population is needed to be resistant for demethylation inhibitor fungicides to be rendered ineffective. Following a single round of selection, the frequency increases by more than 15% with limited fitness penalty detected when no selection is present.
Alec J McCallum   +5 more
wiley   +1 more source

Investigation of Azole Resistance Involving cyp51A and cyp51B Genes in Clinical Aspergillus flavus Isolates

open access: yesPolish Journal of Microbiology
This study aimed to investigate azole resistance mechanisms in Aspergillus flavus, which involve cyp51A and cyp51B genes. Real-time Reverse Transcriptase qPCR method was applied to determine the overexpression of cyp51A and cyp51B genes for 34 A.
Ghorbel Dhoha   +9 more
doaj   +1 more source

The first report of M918L (super‐kdr) and L932F voltage‐gated sodium channel mutations in the English grain aphid (Sitobion avenae)

open access: yesPest Management Science, EarlyView.
The study has identified mutations in the voltage gated sodium channel of the English grain aphid (Sitobion avenae) at M918 and L932, which have not been previously reported in this species. Abstract BACKGROUND The grain aphid, Sitobion avenae Fabricius (Hemiptera: Aphididae), is a vector of yellow dwarf viruses and an important pest of cereals.
Virgile Ballandras   +4 more
wiley   +1 more source

Impact of synonymous mutations in the blaTEM-3 gene on gene expression and Escherichia coli fitness

open access: yesMicrobiology Spectrum
Synonymous mutations (SMs) have a significant effect on the expression of the β-lactamase TEM-3 and the resistance phenotype conferred. Cell-free transcription did not reproduce this effect.
Rinku Dhungana   +3 more
doaj   +1 more source

Discovery and characterisation of succinate dehydrogenase inhibitor resistance in Plenodomus biglobosus (phoma stem canker of oilseed rape)

open access: yesPest Management Science, EarlyView.
SDHI resistance is reported and characterised for the first time in the oilseed rape phoma stem canker pathogen Plenodomus biglobosus (Leptosphaeria biglobosa). We investigate cross‐resistance patterns, associated SDH target‐site mutations, possible fitness costs, and consider the implications for disease and resistance management.
Kevin M King, Jonathan S West
wiley   +1 more source

Decreased DMI sensitivity of Plenodomus biglobosus (phoma of oilseed rape) associated with CYP51 substitution G476S

open access: yesPest Management Science, EarlyView.
Here, we report for the first time a target site mutation in the CYP51 gene of the oilseed rape phoma stem canker fungus Plenodomus biglobosus (Leptosphaeria biglobosa) that is associated with decreased sensitivity to sterol demethylation inhibitor fungicides.
Kevin M King   +4 more
wiley   +1 more source

A Nodule on the Cheek of a Child

open access: yes
JEADV Clinical Practice, EarlyView.
Monika Fida   +5 more
wiley   +1 more source

Formation of Distance‐Based Orientation: Political Identity through Relational Positioning in Israel

open access: yesSymbolic Interaction, EarlyView.
Distance‐based orientation describes how pejorative labels may serve as anchor points for political identity. Existing research on political labeling has largely emphasized stigmatization, overlooking how labels may acquire durability and orienting capacity without losing pejorative force. Drawing on publicly circulating discourse, we trace positioning
Tammar Friedman, Asaf Saadon
wiley   +1 more source

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