Results 141 to 150 of about 660,576 (241)

Chromosome‐Level Genome Assemblies of Two Softshell Turtles with ZZ/ZW Provide Insights into TE‐Driven Recombination Suppression in Sex Chromosomes

Integrative Zoology, EarlyView.
This study presents the first genomic identification and characterization of ZW sex chromosomes in two soft‐shelled turtle species through genome assembly and resequencing. We reveal the structural organization of ZW chromosomes, identifying both pseudoautosomal regions (PARs) and differentiated regions.
Jianjun Liu, Zhiyuan Yang, Min Tang, Tingting Chen, Siqi Liu, Ziyao Meng, Xingjiang Bu, Xingquan Xia, Guang Yang, Liuwang Nie   +9 more
wiley   +1 more source

Metabolome Diversity Enhances Resistance of Intertidal Clams to Thermal Stress

Integrative Zoology, EarlyView.
Meretrix species are widely distributed intertidal bivalves in China with significant ecological and economic importance, which are sensitive to thermal stress. Our results showed that thermal environments of clam habitats shaped metabolome diversity, which can enhance the resistance of intertidal clams to thermal stress.
Zhi Hu, Xiang‐Tao Wei, Xiaonie Lin, Linxuan Ma, Tianzhe Zhang, Yunwei Dong   +5 more
wiley   +1 more source

De novo non-synonymous TBL1XR1 mutation alters Wnt signaling activity

Here we report de novo non-synonymous single-nucleotide variants (SNVs) by conducting whole exome sequencing of 18 trios consisting of Japanese patients with sporadic schizophrenia and their parents.
Kurotaki, Naohiro, Ito, Koki, Imamura, Akira, Ohmori, Tetsuro, Zhu, Xiaolei, Nishi, Akira, Saito, Atsushi, Ono, Shinji, Fukui, Kiyoshi, Kamiya, Atsushi, Shimodera, Shinji, Ueno, Shu-ichi, Ochi, Shinichiro, Numata, Shusuke, Kinoshita, Makoto, Iwata, Nakao, Kato, Yusuke, 田嶋, 敦, Tajima, Atsushi, Imoto, Issei   +19 more
core  

Decades of Enclosure Protection Exert Composite Effects on Grassland Grasshopper Communities

Integrative Zoology, EarlyView.
Decades of enclosure protection have altered grasshopper community structure, with species‐specific effects on population dynamics. For the low‐mobility grasshopper Chorthippus fallax, abundance did not differ strongly between exclosure‐protected and overgrazed areas, but its egg development duration was longer in exclosures. The two C.
Dan‐dan Feng, Hui‐feng Zhao, Ya‐hui Men, Jing Li, Mei‐ling Yang, Cai‐qing Yang, Bing Chen, Ai‐bing Zhang   +7 more
wiley   +1 more source

The Novel Allele, HLA-C*14:167, With a Non-Synonymous Mutation in Exon 1. [PDF]

HLA
Kouniaki D, Athanassiades T, Tsirogianni A.   +2 more
europepmc   +1 more source

Synonymous Mutation in DKC1 Causes Telomerase RNA Insufficiency Manifesting as Familial Pulmonary Fibrosis. [PDF]

Chest, 2020
Gaysinskaya V, Stanley SE, Adam S, Armanios M.   +3 more
europepmc   +1 more source

Comparative Genomics and Functional Evidence for Convergent Adaptation to Hypoxia in Mammals

Integrative Zoology, EarlyView.
This study reveals convergent selection in mammals adapted to hypoxia. Functional assays demonstrate that amino acid mutations reduce oxidative stress, attenuate hypoxia‐induced injury, and modulate the hypoxia‐inducible transcription factor (HIF)‐driven hypoxic response.
Hao Dong, Chunxu Wang, Enqing Pei, Liang Zhao, Simin Chai, Ran Tian   +5 more
wiley   +1 more source

The Novel HLA-A*01:524 Allele With a Non-Synonymous Mutation in Exon 1 Identified in an Individual From North India. [PDF]

HLA
Baranwal AK, Agarwal S, Kumari S, Bairagi N, Bamal M.   +4 more
europepmc   +1 more source

Captive Breeding of the Chinese Alligator Reduces Inbreeding but Increases Genetic Load

Integrative Zoology, EarlyView.
Captive breeding of the Chinese alligator successfully reduced genomic inbreeding but increased the burden of deleterious mutations. Genomic analyses indicate that managing both genetic diversity and genetic load is essential for the long‐term conservation of this critically endangered species.
Yihang Fan, Tao Pan, Nicolas Dussex, Tianming Lan   +3 more
wiley   +1 more source

A naturally synonymous mutation modulates an ERK-centered regulatory network to mediate thermotolerance divergence in Crassostrea oysters. [PDF]

Commun Biol
Wang M, Wang C, Du M, Jiang Z, Chen J, Pang M, Zhang T, Cong R, Wang W, Zhang G, Li L.   +10 more
europepmc   +1 more source