Co-mutation Based Genetic Networks to Infer Temporal Mutation Dynamics in Ancient Human Mitochondrial Genomes. [PDF]
Verma RK +3 more
europepmc +1 more source
ABSTRACT Developing barley grains must balance the use of imported sucrose between soluble sugars and storage starch, but how this balance is controlled remains unclear. Here we show that loss of the plastidial α‐glucan phosphorylase HvPHO1 causes starch and soluble sugars to accumulate concurrently in barley grains.
Yulong Li +17 more
wiley +1 more source
Plasmodium falciparum non-synonymous Kelch13 mutations mediating artemisinin resistance in East Africa: A systematic review and meta-analysis: 2014-2024. [PDF]
Kapesa A +6 more
europepmc +1 more source
Comparative Genome‐Wide Association Studies of Metabolites and Grain‐Related Traits in Common Wheat
ABSTRACT The metabolome is highly diverse and the closest layer to phenotype; therefore, it is commonly regarded as a bridge between the genome and phenome in plants. Here, we performed large‐scale metabolome analysis using liquid chromatography–tandem mass spectrometry (LC–MS/MS) and 33 grain‐related traits in a diverse panel of natural accessions and
Guoguo Lv +11 more
wiley +1 more source
Synonymous codon-optimized multiplex qPCR for simultaneous detection of <i>Helicobacter pylori</i> and precise drug resistance profiling in infected individuals. [PDF]
Li H-L +9 more
europepmc +1 more source
ABSTRACT Brassica napus (canola) is a significant contributor to the world's oil production and is cultivated across continents, yet acidic soils with aluminium (Al3+) and manganese (Mn2+) toxicities limit its production. The genetic determinants underlying natural variation for acidic soil tolerance in canola are unknown and need to be determined ...
Harsh Raman +13 more
wiley +1 more source
Genomic Epidemiology and Clinical Characteristics of Mpox Lineage C.1 Outbreak in Thailand, 2023-2024. [PDF]
Suwannakarn K +12 more
europepmc +1 more source
Hidden Strategies Beneath a Single Nucleotide: Contrasting Physiology in Lichen Photobiont Strains
ABSTRACT Lichen photobionts exhibit significant physiological variability with important ecological implications. While this variability is relatively well studied at the interspecific level, it has rarely been examined at the intraspecific level. Here, we investigated the physiological responses to temperature and irradiance of two Trebouxia lynniae ...
Miguel Blázquez +14 more
wiley +1 more source
SOD1:c.118G>A mutation in the Cimarrón Uruguayo dog: prevalence, drift dynamics, and structural effects. [PDF]
Artigas R +6 more
europepmc +1 more source
UV signature mutation hyperhotspots as genomic dosimeters
Recurrent UV signature mutations are a sensitive and specific indicator of sun exposure. UV signature mutations (C → T mutations at dipyrimidine sites) were quantified using Duplex Sequencing and a stringent mutation calling protocol to identify true low‐abundance mutations.
Vijay Menon +12 more
wiley +1 more source

