Results 11 to 20 of about 76,148 (125)

Comparative biochemical analysis of synovial fluid constituents in infected cases following total knee replacement [PDF]

Гений oртопедии, 2019
Introduction Biochemical parameters of synovial fluid constituents were reviewed in patients prior to total knee replacement (TKR). The diagnostic value of certain biochemical tests was identified as prognostic factors in the development of infection ...
Elena L. Matveeva, Zinaida S. Naumenko, Elena S. Spirkina, Anna G. Gasanova, Irina A. Talashova, Anastasia A. Rakhmatulina   +5 more
doaj   +1 more source

Hyperlipidemic microenvironment conditionates damage mechanisms in human chondrocytes by oxidative stress

Lipids in Health and Disease, 2017
Background Currently, two pathogenic pathways describe the role of obesity in osteoarthritis (OA); one through biomechanical stress, and the other by the contribution of systemic inflammation.
Daniel Medina-Luna, Mónica Guadalupe Santamaría-Olmedo, Yessica Zamudio-Cuevas, Karina Martínez-Flores, Javier Fernández-Torres, Gabriela Angélica Martínez-Nava, Denise Clavijo-Cornejo, Cristina Hernández-Díaz, Anell Olivos-Meza, Luis Enrique Gomez-Quiroz, María Concepción Gutiérrez-Ruiz, Carlos Pineda, Francisco Blanco, Anthony M. Reginato, Alberto López-Reyes   +14 more
doaj   +1 more source

The concordance between preoperative aspiration and intraoperative synovial fluid culture results: intraoperative synovial fluid re-cultures are necessary whether the preoperative aspiration culture is positive or not

BMC Infectious Diseases, 2021
Aims Preoperative aspiration culture and intraoperative cultures play pivotal roles in periprosthetic joint infection (PJI) diagnosis and pathogen identification.
Hao Li, Chi Xu, LiBo Hao, Wei Chai, Fu Jun, Jiying Chen   +5 more
doaj   +1 more source

A Systemic and Local Comparison of Senescence in an Acute Anterior Cruciate Ligament Injury—A Pilot Case Series

Life, 2023
Background: Senescence, a characteristic of cellular aging and inflammation, has been linked to the acceleration of osteoarthritis. The purpose of this study is to prospectively identify, measure, and compare senescent profiles in synovial fluid and ...
Robert A. Waltz, Kaitlyn E. Whitney, Victoria R. Duke, Heidi Kloser, Charles Huard, Matthew T. Provencher, Marc J. Philippon, Chelsea Bahney, Jonathan A. Godin, Johnny Huard   +9 more
doaj   +1 more source

An injectable, self-healing and MMP-inhibiting hyaluronic acid gel via iron coordination [PDF]

, 2021
Regulating the activity of matrix metalloproteinases (MMPs) is a potential strategy for osteoarthritis (OA) therapy, although delivering this effect in a spatially and temporally localised fashion remains a challenge. Here, we report an injectable and self-healing hydrogel enabling factor-free MMP regulation and biomechanical competence in situ.
arxiv   +1 more source

Molecular dynamics simulations of the affinity of chitin and chitosan for collagen: the effect of pH and the presence of sodium and calcium cations [PDF]

Progress on Chemistry and Application of Chitin and Its Derivatives 28 (2023): 136-50, 2023
Chitosan and chitin are promising biopolymers used in many areas including biomedical applications, such as tissue engineering and viscosupplementation. Chitosan shares similar properties with hyaluronan, a natural component of synovial fluid, making it a good candidate for joint disease treatment.
arxiv   +1 more source

Hyaluronic acid synthesis, degradation, and crosslinking in equine osteoarthritis: TNF-α-TSG-6-mediated HC-HA formation

Arthritis Research & Therapy, 2021
Background TNF-α-stimulated gene 6 (TSG-6) protein, a TNF-α-responsive hyaladherin, possesses enzymatic activity that can catalyze covalent crosslinks of the polysaccharide hyaluronic acid (HA) to another protein to form heavy chain-hyaluronic acid (HC ...
Diana C. Fasanello, Jin Su, Siyu Deng, Rose Yin, Marshall J. Colville, Joshua M. Berenson, Carolyn M. Kelly, Heather Freer, Alicia Rollins, Bettina Wagner, Felipe Rivas, Adam R. Hall, Elaheh Rahbar, Paul L. DeAngelis, Matthew J. Paszek, Heidi L. Reesink   +15 more
doaj   +1 more source

Characterization of the porcine synovial fluid proteome and a comparison to the plasma proteome

Data in Brief, 2015
Synovial fluid is present in all joint cavities, and protects the articular cartilage surfaces in large by lubricating the joint, thus reducing friction. Several studies have described changes in the protein composition of synovial fluid in patients with
Tue Bjerg Bennike, Omar Barnaby, Hanno Steen, Allan Stensballe   +3 more
doaj   +1 more source

On Modeling the Response of Synovial Fluid: Unsteady Flow of a Shear-Thinning, Chemically-Reacting Fluid Mixture [PDF]

Bridges, Craig, Satish Karra, and K. R. Rajagopal. "On modeling the response of the synovial fluid: Unsteady flow of a shear-thinning, chemically-reacting fluid mixture." Computers & Mathematics with Applications 60.8 (2010): 2333-2349, 2010
We study the flow of a shear-thinning, chemically-reacting fluid that could be used to model the flow of the synovial fluid. The actual geometry where the flow of the synovial fluid takes place is very complicated, and therefore the governing equations are not amenable to simple mathematical analysis.
arxiv   +1 more source

Investigation on the Influence of Synovial Fluid and Vitreous Humour on Avulsion Wounds Healing in Rabbits [PDF]

Archives of Razi Institute, 2021
In the present study, we investigated the efficacy of vitreous humour and synovial fluid on avulsion wound healing in a rabbit’s model. The vitreous humour is a fluid that resembles gel consisting of approximately 98–99% water, little hyaluronic acid ...
L. A Naeem, Z. B Abdul Kareem, M. M Jassim, A. A Khalaf, Z. A Jabbar   +4 more
doaj   +1 more source