Results 31 to 40 of about 2,226,700 (403)

Investigation of synovial fluid induced Staphylococcus aureus aggregate development and its impact on surface attachment and biofilm formation

PLoS ONE, 2020
Periprosthetic joint infections (PJIs) are a devastating complication that occurs in 2% of patients following joint replacement. These infections are costly and difficult to treat, often requiring multiple corrective surgeries and prolonged antimicrobial
Matthew J. Pestrak, T. Gupta, D. Dusane, D. V. Guzior, Amelia Staats, Janette M. Harro, A. Horswill, P. Stoodley   +7 more
semanticscholar   +1 more source

Thermogenic diagnosis of periprosthetic joint infection by microcalorimetry of synovial fluid

BMC Musculoskeletal Disorders, 2020
Background Synovial fluid culture is the standard investigation for the preoperative diagnosis of periprosthetic joint infection (PJI). However, the culture has limited sensitivity and requires several days until result.
Christian Morgenstern, Nora Renz, Sabrina Cabric, Elena Maiolo, Carsten Perka, Andrej Trampuz   +5 more
doaj   +1 more source

Investigation of synovial fluid lubricants and inflammatory cytokines in the horse: a comparison of recombinant equine interleukin 1 beta-induced synovitis and joint lavage models

BMC Veterinary Research, 2021
Background Lameness is a debilitating condition in equine athletes that leads to more performance limitation and loss of use than any other medical condition.
Amanda Watkins, Diana Fasanello, Darko Stefanovski, Sydney Schurer, Katherine Caracappa, Albert D’Agostino, Emily Costello, Heather Freer, Alicia Rollins, Claire Read, Jin Su, Marshall Colville, Matthew Paszek, Bettina Wagner, Heidi Reesink   +14 more
doaj   +1 more source

Activation of inflammation and resolution pathways of lipid mediators in synovial fluid from patients with severe rheumatoid arthritis compared with severe osteoarthritis

Asia Pacific Allergy, 2020
Background The upregulation of the cyclooxygenase and lipoxygenase pathways of arachidonic acid is thought to be involved in the development of rheumatoid arthritis.
Yutaka Sano, S. Toyoshima, Y. Miki, Y. Taketomi, Mana Ito, Hyunho Lee, S. Saito, M. Murakami, Y. Okayama   +8 more
semanticscholar   +1 more source

Neutrophil extracellular trap clearance by synovial macrophages in gout

Arthritis Research & Therapy, 2021
Background Monosodium urate (MSU) crystals, i.e., the central etiological factors in gouty arthritis, induce the formation of neutrophil extracellular traps (NETs).
Ji Hye Jeong, Su Jin Choi, Soo Min Ahn, Ji Seon Oh, Yong-Gil Kim, Chang-Keun Lee, Bin Yoo, Seokchan Hong   +7 more
doaj   +1 more source

Quantification of chondroitin sulfate, hyaluronic acid and N-glycans in synovial fluid – A technical performance study

Osteoarthritis and Cartilage Open, 2023
Objective: To validate a quantitative high performance liquid chromatography (HPLC) assay for chondroitin sulfate (CS) and hyaluronic acid (HA) in synovial fluid, and to analyze glycan-patterns in patient samples.
Elin Andersson, Emil Tykesson, L. Stefan Lohmander, Niclas G. Karlsson, Chunsheng Jin, Ekaterina Mirgorodskaya, Per Swärd, André Struglics   +7 more
doaj   +1 more source

Hyperlipidemic microenvironment conditionates damage mechanisms in human chondrocytes by oxidative stress

Lipids in Health and Disease, 2017
Background Currently, two pathogenic pathways describe the role of obesity in osteoarthritis (OA); one through biomechanical stress, and the other by the contribution of systemic inflammation.
Daniel Medina-Luna, Mónica Guadalupe Santamaría-Olmedo, Yessica Zamudio-Cuevas, Karina Martínez-Flores, Javier Fernández-Torres, Gabriela Angélica Martínez-Nava, Denise Clavijo-Cornejo, Cristina Hernández-Díaz, Anell Olivos-Meza, Luis Enrique Gomez-Quiroz, María Concepción Gutiérrez-Ruiz, Carlos Pineda, Francisco Blanco, Anthony M. Reginato, Alberto López-Reyes   +14 more
doaj   +1 more source

The concordance between preoperative aspiration and intraoperative synovial fluid culture results: intraoperative synovial fluid re-cultures are necessary whether the preoperative aspiration culture is positive or not

BMC Infectious Diseases, 2021
Aims Preoperative aspiration culture and intraoperative cultures play pivotal roles in periprosthetic joint infection (PJI) diagnosis and pathogen identification.
Hao Li, Chi Xu, LiBo Hao, Wei Chai, Fu Jun, Jiying Chen   +5 more
doaj   +1 more source

A Systemic and Local Comparison of Senescence in an Acute Anterior Cruciate Ligament Injury—A Pilot Case Series

Life, 2023
Background: Senescence, a characteristic of cellular aging and inflammation, has been linked to the acceleration of osteoarthritis. The purpose of this study is to prospectively identify, measure, and compare senescent profiles in synovial fluid and ...
Robert A. Waltz, Kaitlyn E. Whitney, Victoria R. Duke, Heidi Kloser, Charles Huard, Matthew T. Provencher, Marc J. Philippon, Chelsea Bahney, Jonathan A. Godin, Johnny Huard   +9 more
doaj   +1 more source

Protein concentration of synovial fluid in chronic rheumatoid arthritis. Estimation of protein in the synovial fluid of chronic rheumatoid arthritis by gel filtration and paper electrophoresis [PDF]

, 1968
For the purpose to reveal the characteris6cs of the synovial fluid of the chronic rheumatoid arthritis the proteins of the synovial fluid and blood serum have been analysed by employing the methods of electrophoresis, gel filtration on Sephadex G-200 ...
Seno, Takashi
core   +1 more source