In the evaluation of artificial joint disorders, synovial fluid analysis can become a very efficient diagnostic tool. This chapter explains the role of synovial fluid cytological analysis in diagnosing prosthetic joint infection (PJI). Recommended cutoff values for diagnosing PJI for leukocyte count are 1,700 cells/μL and for neutrophils 65 ...
Mihalič, Rene, Terčič, Dunja
openaire +2 more sources
Background Acrolein is a known pro-inflammatory toxic aldehyde, propagating cellular damage and tissue inflammation in humans and animal models of various diseases.
Seth A. Herr +5 more
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Synovial joint lubrication – does nature teach more effective engineering lubrication strategies? [PDF]
Nature shows numerous examples of systems which show energy efficiency, elegance in their design and optimum use of materials. Biomimetics is an emerging field of research in engineering and successes have been documented in the diverse fields of ...
Liskiewicz, T. +3 more
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Synovial fluid IL-1β appears useful for the diagnosis of chronic periprosthetic joint infection
Purpose The purpose of this study was to investigate the role of synovial fluid interleukin (IL)-1β in diagnosing chronic periprosthetic joint infection (PJI) and to identify the optimal threshold of synovial fluid IL-1β for differentiating chronic PJI ...
Hai Wang +3 more
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Immunohistochemical Analysis of IL-1 Receptor 1 In the Discs of Patients with Temporomandibular Joint Dysfunction [PDF]
Objective Temporomandibular joint dysfunction (TMD) may affect a patient’s quality of life, and one of the etiologies can be anterior disc displacement with reduction (ADDwR) and anterior disc displacement without reduction (ADDWoR).
Almeida, Luis Eduardo +8 more
core +2 more sources
Background: Neurocytokines may upregulate or downregulate neuropathic pain. We hypothesized that dextrose (D-glucose) injections for therapeutic purposes (dextrose prolotherapy: DPT) in painful knee osteoarthritis (KOA) would favorably affect synovial ...
Gastón Andrés Topol +6 more
doaj +1 more source
Differential patterns of PMN-elastase and type III procollagen peptide in knee joint effusions due to acute and chronic sports injuries [PDF]
In 38 traumatic knee joint effusions the proteolytic enzyme PMN-elastase (PMN-E) and the repair marker procollagen III aminoterminal peptide (PIIINP) were determined.
A Billing +29 more
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Driving chronicity in rheumatoid arthritis: perpetuating role of myeloid cells [PDF]
Acute inflammation is a complex and tightly regulated homeostatic process that includes leukocyte migration from the vasculature into tissues to eliminate the pathogen/injury, followed by a pro-resolving response promoting tissue repair.
Achuthan +115 more
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Optimized “In Vitro” Culture Conditions for Human Rheumatoid Arthritis Synovial Fibroblasts
The composition of synovial fluid in rheumatoid arthritis (RA) is complex and strongly influences the microenvironment of joints and it is an inseparable element of the disease.
Claudia Casnici +8 more
doaj +1 more source
The liver X receptor pathway is highly upregulated in rheumatoid arthritis synovial macrophages and potentiates TLR-driven cytokine release [PDF]
<p>Objectives: Macrophages are central to the inflammatory processes driving rheumatoid arthritis (RA) synovitis. The molecular pathways that are induced in synovial macrophages and thereby promote RA disease pathology remain poorly understood.</
Ananth +42 more
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