Results 41 to 50 of about 2,164,308 (357)

Preliminary Report: Osteoarthritis and Rheumatoid Arthritis Synovial Fluid Increased Osteoclastogenesis In Vitro by Monocyte Differentiation Pathway Regulating Cytokines

Mediators of Inflammation, 2022
Background. Rheumatoid arthritis (RA) and osteoarthritis (OA) are common joint diseases associated with changes in local, as well as systemic bone structure and osteoclast function.
Jani Luukkonen, Johanna Huhtakangas, Sanna Palosaari, Juha Tuukkanen, Olli Vuolteenaho, Petri Lehenkari   +5 more
doaj   +1 more source

Gender-specific differential expression of exosomal miRNA in synovial fluid of patients with osteoarthritis

Scientific Reports, 2017
The pathogenesis of osteoarthritis (OA) is poorly understood, and therapeutic approaches are limited to preventing progression of the disease. Recent studies have shown that exosomes play a vital role in cell-to-cell communication, and pathogenesis of ...
R. Kolhe, M. Hunter, Siyang Liu, R. Jadeja, C. Pundkar, A. Mondal, B. Mendhe, M. Drewry, M. Rojiani, Yutao Liu, C. Isales, R. Guldberg, M. Hamrick, S. Fulzele   +13 more
semanticscholar   +1 more source

A Comparison Between Rheological Properties of Intra-articular Hyaluronic Acid Preparations and Reported Human Synovial Fluid

Advances in Therapy, 2018
IntroductionThis study aims to compare the properties of currently available intra-articular hyaluronate (IA-HA) products widely available in the USA to those of healthy knee synovial fluid with respect to their bulk rheological properties.
Mathew Nicholls, Ajay Manjoo, Peter Shaw, Faizan Niazi, JE Rosen   +4 more
semanticscholar   +1 more source

Children with oligoarticular juvenile idiopathic arthritis have skewed synovial monocyte polarization pattern with functional impairment—a distinct inflammatory pattern for oligoarticular juvenile arthritis

Arthritis Research & Therapy, 2020
Background Juvenile idiopathic arthritis (JIA) is an umbrella term of inflammatory joint diseases in children. Oligoarthritis is the most common form in the Western world, representing roughly 60% of all patients.
Tobias Schmidt, Elisabet Berthold, Sabine Arve-Butler, Birgitta Gullstrand, Anki Mossberg, Fredrik Kahn, Anders A. Bengtsson, Bengt Månsson, Robin Kahn   +8 more
doaj   +1 more source

Synovial Fluid Fatty Acid Profiles Differ between Osteoarthritis and Healthy Patients

Cartilage, 2018
Objective Free fatty acids (FAs) may influence cartilage metabolism and osteoarthritis (OA) disease progression. It is not clearly studied which FAs are present in the synovial fluid of knee joints and whether there are differences in FA content between ...
Arne van de Vyver, S. Clockaerts, C. H. van de Lest, Wu Wei, J. Verhaar, G. V. van Osch, Y. Bastiaansen‐Jenniskens   +6 more
semanticscholar   +1 more source

Synovial fluid IL-1β appears useful for the diagnosis of chronic periprosthetic joint infection

Journal of Orthopaedic Surgery and Research, 2021
Purpose The purpose of this study was to investigate the role of synovial fluid interleukin (IL)-1β in diagnosing chronic periprosthetic joint infection (PJI) and to identify the optimal threshold of synovial fluid IL-1β for differentiating chronic PJI ...
Hai Wang, Leilei Qin, Jiawei Wang, Wei Huang   +3 more
doaj   +1 more source

Evidence of acrolein in synovial fluid of dogs with osteoarthritis as a potential inflammatory biomarker

BMC Musculoskeletal Disorders, 2021
Background Acrolein is a known pro-inflammatory toxic aldehyde, propagating cellular damage and tissue inflammation in humans and animal models of various diseases.
Seth A. Herr, Sarah Malek, Mark C. Rochat, George E. Moore, Jeff C. Ko, Riyi Shi   +5 more
doaj   +1 more source

Hyaluronan concentration and size distribution in human knee synovial fluid: variations with age and cartilage degeneration

Arthritis Research & Therapy, 2016
BackgroundOne potential mechanism for early superficial cartilage wear in normal joints is alteration of the lubricant content and quality of synovial fluid.
Michele M. Temple-Wong, Shuwen Ren, P. Quach, Bradley C. Hansen, Albert C. Chen, Akihiko Hasegawa, D. D’Lima, J. Koziol, K. Masuda, M. Lotz, R. Sah   +10 more
semanticscholar   +1 more source

Dextrose Prolotherapy for Symptomatic Grade IV Knee Osteoarthritis: A Pilot Study of Early and Longer-Term Analgesia and Pain-Specific Cytokine Concentrations

Clinics and Practice, 2022
Background: Neurocytokines may upregulate or downregulate neuropathic pain. We hypothesized that dextrose (D-glucose) injections for therapeutic purposes (dextrose prolotherapy: DPT) in painful knee osteoarthritis (KOA) would favorably affect synovial ...
Gastón Andrés Topol, Ines Guerrero Pestalardo, Kenneth Dean Reeves, Fernando Elias, Neven J. Steinmetz, An-Lin Cheng, David Rabago   +6 more
doaj   +1 more source

Effects of ACL Reconstructive Surgery on Temporal Variations of Cytokine Levels in Synovial Fluid

Mediators of Inflammation, 2016
Anterior cruciate ligament (ACL) reconstruction restores knee stability but does not reduce the incidence of posttraumatic osteoarthritis induced by inflammatory cytokines.
M. Bigoni, M. Turati, M. Gandolla, P. Sacerdote, M. Piatti, A. Castelnuovo, S. Franchi, M. Gorla, D. Munegato, D. Gaddi, A. Pedrocchi, R. J. Omeljaniuk, V. Locatelli, A. Torsello   +13 more
semanticscholar   +1 more source