Synovial membrane mesenchymal stem cells: past life, current situation, and application in bone and joint diseases [PDF]
Stem Cell Research & Therapy, 2020 Mesenchymal stem cells (MSCs) can be isolated from not only bone marrow, but also various adult mesenchymal tissues such as periosteum, skeletal muscle, and adipose tissue.
Na Li +8 more
doaj +3 more sources
Respective stemness and chondrogenic potential of mesenchymal stem cells isolated from human bone marrow, synovial membrane, and synovial fluid [PDF]
Stem Cell Res Ther, 2020 Background MSCs isolated from bone marrow (BM-MSCs) have well-established chondrogenic potential, but MSCs derived from the synovial membrane (SM-MSCs) and synovial fluid (SF-MSCs) are thought to possess superior chondrogenicity.
Paul Neybecker +8 more
semanticscholar +3 more sources
Co-culture of osteochondral explants and synovial membrane as in vitro model for osteoarthritis. [PDF]
PLoS ONE, 2019 The purpose of the current study was to establish an in vitro model for osteoarthritis (OA) by co-culture of osteochondral and synovial membrane explants.
Eva Haltmayer +9 more
doaj +3 more sources
Osteoarthritis and Cartilage, 2020 OBJECTIVE Synovial inflammation is one of the most characteristic events in different types of arthritis, including Osteoarthritis (OA). Emerging evidence also suggests the involvement of lipids in the regulation of inflammatory processes.
Beatriz Rocha +6 more
openalex +2 more sources
CEMIP (KIAA1199) regulates inflammation, hyperplasia and fibrosis in osteoarthritis synovial membrane [PDF]
Cell Mol Life Sci, 2022 Osteoarthritis (OA) synovial membrane is mainly characterized by low-grade inflammation, hyperplasia with increased cell proliferation and fibrosis. We previously underscored a critical role for CEMIP in fibrosis of OA cartilage.
C. Deroyer +10 more
semanticscholar +2 more sources
Frontiers in Immunology, 2022 Rheumatoid arthritis (RA) is a systemic autoimmune disease during which fibroblast-like synoviocytes (FLS) contribute to both joint inflammation and destruction. FLS represent the core component of the synovial membrane.
Dorra Elhaj Mahmoud +10 more
doaj +2 more sources
Contribution of Infrapatellar Fat Pad and Synovial Membrane to Knee Osteoarthritis Pain [PDF]
Biomed Res Int, 2019 Osteoarthritis (OA) is the most common form of joint disease and a major cause of pain and disability in the adult population. Interestingly, there are patients with symptomatic OA displaying pain, while patients with asymptomatic OA that do not ...
E. Belluzzi +11 more
semanticscholar +2 more sources
Characterization of mesenchymal stem cells derived from the equine synovial fluid and membrane [PDF]
BMC Veterinary Research, 2015 BackgroundIsolation of mesenchymal stem cells (MSCs) in equines, has been reported for different tissues including bone marrow, adipose, umbilical cord, peripheral blood, and yolk sac.
Aline Ambrogi Franco Prado +5 more
openalex +2 more sources
Synovial membrane-derived mesenchymal progenitor cells from osteoarthritic joints in dogs possess lower chondrogenic-, and higher osteogenic capacity compared to normal joints [PDF]
Stem Cell Research & Therapy, 2022 Background Synovial membrane-derived mesenchymal progenitor cells (SM-MPCs) are a promising candidate for the cell-based treatment of osteoarthritis (OA) considering their in vitro and in vivo capacity for cartilage repair.
M. Teunissen +9 more
doaj +2 more sources
Synovial Macrophages: Past Life, Current Situation, and Application in Inflammatory Arthritis
Frontiers in Immunology, 2022 Inflammatory arthritis is an inflammatory disease that involves the joints and surrounding tissues. Synovial hyperplasia often presents when joints become inflamed due to immune cell infiltration.
Lin-Kun Bai +6 more
doaj +2 more sources