Results 11 to 20 of about 2,054,522 (273)

Lipidomic Profiling in Synovial Tissue. [PDF]

Front Med (Lausanne), 2022
The analysis of synovial tissue offers the potential for the comprehensive characterization of cell types involved in arthritis pathogenesis. The studies performed to date in synovial tissue have made it possible to define synovial pathotypes, which relate to disease severity and response to treatment.
Coras R, Murillo-Saich JD, Singh AG, Kavanaugh A, Guma M.   +4 more
europepmc   +8 more sources

Synovial tissue macrophages: friend or foe? [PDF]

RMD Open, 2017
Healthy synovial tissue includes a lining layer of synovial fibroblasts and macrophages. The influx of leucocytes during active rheumatoid arthritis (RA) includes monocytes that differentiate locally into proinflammatory macrophages, and these produce ...
Stefano Alivernini, Mariola Kurowska-Stolarska   +1 more
doaj   +2 more sources

Synovial tissue analysis in clinical trials.

The Journal of rheumatology, 2005
Synovial tissue analysis has considerable potential for future randomized controlled trials (RCT). The synovial membrane is the target tissue in treatment strategies of rheumatoid arthritis and other arthropathies. Effective modulation of synovitis is critical when attempting to control symptoms and signs, to prevent joint damage, and to maintain ...
Bresnihan, Barry, Baeten, Dominique, Firestein, Gary S, Fitzgerald, Oliver M, Gerlag, Danielle M, Haringman, Jasper J, McInnes, Iain B, Reece, Richard J, Smith, Malcolm Douglas, Ulfgren, Ann-Kristen, Veale, Douglas J, Tak, Paul Peter   +11 more
core   +10 more sources

TISSUE DIFFERENTIATION IN MALIGNANT SYNOVIAL TUMOURS

The Journal of Bone and Joint Surgery. British volume, 1952
1. A series of twenty-one cases of synovial tumour is tabled and the histological appearances are discussed. 2. The characteristic histological forms, (a) mucin formation, (b) synovial spaces, (c) endothelial and "gland" spaces and (d) epithelium-like tissue, are described. 3. These all arise by differentiation of connective tissue cells which occur
E. S. J. King
openaire   +3 more sources

The ontogeny of synovial tissue macrophages. [PDF]

Front Immunol
Macrophages are essential components of all body tissues, including the synovium. Tissue macrophages originate either from embryonically seeded “primitive” macrophages or from bone marrow-derived monocytes. In adults, both sources contribute to macrophage populations, with their relative proportions varying across tissues and between steady-state and ...
Hutton J, Sun W, Hasegawa T.
europepmc   +5 more sources

Caracterització de la sinovitis mitjançant mètodes artroscòpics i immunohistoquímics. Valor diagnòstic i pronòstic [PDF]

, 2006
[cat] La membrana sinovial, és el lloc on s'inicia i es perpetua el procés inflamatori que caracteritza a les diferents artropaties inflamatòries. A diferència d'altres òrgans no té una estructura definida, motiu pel qual el context on es produeix la ...
Salvador Alarcón, Georgina
core   +6 more sources

Effects of Glutaraldehyde on Synovial Tissue [PDF]

Journal of International Medical Research, 2003
This study investigated the effect of glutaraldehyde on the synovial tissue of rabbits. Four different concentrations of glutaraldehyde solution were injected into one knee and the contralateral glenohumeral joint of rabbits in group A to group D. The concentration levels used in group A and group B were 1000 ppm and 100 ppm, respectively.
Akpinar, F, Tosun, N, Dogan, A
openaire   +3 more sources

Chondroprogenitor cells of synovial tissue [PDF]

Arthritis & Rheumatism, 1999
To assess the chondrogenic potential of cells within the synovium.Explants of synovium taken from various sites in the joint were embedded in agarose and cultured with transforming growth factor beta1 (TGFbeta1) to assess their chondrogenic potential.
K, Nishimura, L A, Solchaga, A I, Caplan, J U, Yoo, V M, Goldberg, B, Johnstone   +5 more
openaire   +2 more sources

Synovial tissue research [PDF]

Nature Reviews. Rheumatology, 2017
The synovium is the major target tissue of inflammatory arthritides such as rheumatoid arthritis. The study of synovial tissue has advanced considerably throughout the past few decades from arthroplasty and blind needle biopsy to the use of arthroscopic and ultrasonographic technologies that enable easier visualization and improve the reliability of ...
Orr, Carl, Vieira-Sousa, Elsa, Boyle, David L, Buch, Maya H; id_orcid 0000-0002-8962-5642, Buckley, Christopher D, Cañete, Juan D, Catrina, Anca I, Choy, Ernest H S, Emery, Paul, Fearon, Ursula, Filer, Andrew, Gerlag, Danielle, Humby, Frances, Isaacs, John D, Just, Søren A, Lauwerys, Bernard R, Le Goff, Benoit, Manzo, Antonio, McGarry, Trudy, McInnes, Iain B, Najm, Aurélie, Pitzalis, Constantino, Pratt, Arthur, Smith, Malcolm, Tak, Paul P, Thurlings, Rogier, Fonseca, João E, Veale, Douglas J, Tas, Sander W   +28 more
openaire   +10 more sources

Targeting human synovium using homing peptides identified by in vivo phage display [PDF]

, 2009
PhDRheumatoid arthritis (RA) is a chronic inflammatory condition affecting diarthrodial synovial joints. Non-random patterns of inflammatory cell recruitment suggest the presence of synovial-specific vascular determinants which enable recruitment of ...
Garrood, Toby
core   +3 more sources