A tissue kallikrein in the synovial fluid of patients with rheumatoid arthritis [PDF]
Tissue kallikrein is an enzyme that forms the vasoactive peptide kallidin from an endogenous substrate L-kininogen. Tissue kallikrein has been identified in joint fluids and in inflammatory infiltrates within synovial membranes.
Bhoola, K. D. +5 more
core +1 more source
Editorial: Synovial tissue biopsy research. [PDF]
Veale DJ +3 more
europepmc +4 more sources
A complex inflammatory process mediated by proinflammatory cytokines and prostaglandins commonly occurs in the synovial tissue of patients with joint trauma (JT), osteoarthritis (OA), and rheumatoid arthritis (RA).
Mohammed A. Al-Madol +8 more
doaj +1 more source
Extraction and identification of synovial tissue-derived exosomes by different separation techniques
Objective The aim of this study is to compare the efficiency of different separation techniques for extracting synovial tissue-derived exosomes. Methods The synovial tissue discarded during knee arthroscopy or total knee arthroplasty surgery was ...
Pu Chen +6 more
doaj +1 more source
Synovial joints: Mechanobiology and tissue engineering of articular cartilage and synovial fluid [PDF]
This chapter provides an overview of the components of synovial joints including articular cartilage, synovium, and synovial fluid. Focus is placed on the biomechanical properties of these tissues and models of their behavior.
Meinert, C. +11 more
core +1 more source
Disruption of rhythms of molecular clocks in primary synovial fibroblasts of patients with osteoarthritis and rheumatoid arthritis, role of IL-1;2/TNF [PDF]
Introduction: Circadian rhythms play an important role in the body and in single cells. Rhythms of molecular clocks have not been investigated in synovial fibroblasts (SF) of patients with osteoarthritis (OA) and rheumatoid arthritis (RA).
Haas, Stefanie +3 more
core +1 more source
The histopathological and molecular analysis of the synovial tissue has contributed to fundamental advances in our comprehension of arthritis pathogenesis and of the mechanisms of action of currently available treatments.
A. Manzo +3 more
doaj +1 more source
Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin [PDF]
Pathological processes involved in the initiation of rheumatoid synovitis remain unclear. We undertook the present study to identify immune and stromal processes that are present soon after the clinical onset of rheumatoid arthritis ( RA) by assessing a ...
Lee, CY +28 more
core +1 more source
Background Synovial sarcoma is an uncommon soft tissue tumor of soft tissue, characterized by a specific SS18 rearrangement. It generally manifests as a lesion composed of monomorphic spindle cells and sometimes shows variable epithelial differentiation.
Ying Chen +5 more
doaj +1 more source
Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early Rheumatoid Arthritis: an observational study. [PDF]
INTRODUCTION: Neovascularization contributes to the development of sustained synovial inflammation in the early stages of Rheumatoid Arthritis. Ultrasound (US) provides an indirect method of assessing synovial blood flow and has been shown to correlate ...
Kelly, S +23 more
core +1 more source

