Results 111 to 120 of about 19,285 (227)

Abnormal Expression of DICER1 Leads to Dysregulation of Inflammatory Effectors in Human Synoviocytes

Mediators of Inflammation, 2019
Dysregulation of multiple microRNAs widely takes place during rheumatoid arthritis (RA) and experimental arthritides. This study is performed to explore the possible mechanism underlying DICER1 deficiency-mediated inflammation in human synoviocytes SW982.
Congshan Jiang, Jing Xu, Wenhua Zhu, Yongsong Cai, Si Wang, Yuanxu Guo, Ke Xu, Manman Geng, Nazim Hussain, Yan Han, Fujun Zhang, Qilan Ning, Liesu Meng, Shemin Lu   +13 more
doaj   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, Volume 46, Issue 6, Page 1897-1921, November 2026.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source

Oxygen and indocyanine green loaded phase-transition nanoparticle-mediated photo-sonodynamic cytotoxic effects on rheumatoid arthritis fibroblast-like synoviocytes

International Journal of Nanomedicine, 2017
Qin Tang,1–3 Jianyu Cui,1 Zhonghua Tian,1 Jiangchuan Sun,4 Zhigang Wang,2 Shufang Chang,4 Shenyin Zhu1 1Department of Pharmacy, First Affiliated Hospital of Chongqing Medical University, 2Department of Ultrasound, Institute of Ultrasound Imaging ...
Tang Q, Cui J, Tian Z, Sun J, Wang Z, Chang S, Zhu S   +6 more
doaj  

Updates on intra‐articular corticosteroid administration in horses

Equine Veterinary Education, Volume 38, Issue 11, Page 600-610, November 2026.
Summary Intra‐articular (IA) corticosteroid administration in equine athletes has gained increased attention recently, particularly in racing. Despite widespread corticosteroid use in equine practice for decades, there are still a lack of equine‐specific studies to address key questions related to their use.
K. Tanner, L. Bass, C. Kawcak, L. V. Schnabel, K. L. Hallowell, L. M. Pezzanite   +5 more
wiley   +1 more source

The emerging fibroblast‐like synoviocyte channelome [PDF]

Experimental Physiology, 2018
Simon R. Tew, Richard Barrett‐Jolley
openaire   +3 more sources

Differential MMP-2 Activity Induced by Mechanical Compression and Inflammatory Factors in Human Synoviocytes [PDF]

, 2010
The anterior cruciate ligament, posterior cruciate ligament, cartilage and meniscus in human knee joint have poor healing ability. Accumulation of MMPs in the joint fluids due to knee injury has been considered as the main reason.
Yequan Wang, Zhenyu Tang, Ruyue Xue, Xinyan Tang, Dianming Jiang, KL Paul Sung, Li Yang, Wei Huang, Jin Zhang, Peter Chen   +9 more
core   +1 more source

Adrenal Steroids Modulate Fibroblast-Like Synoviocytes Response During B. abortus Infection

Frontiers in Endocrinology, 2019
Brucella abortus stimulates an inflammatory immune response that stimulates the endocrine system, inducing the secretion of dehydroepiandrosterone (DHEA) and cortisol. In humans, the active disease is generally present as osteoarticular brucellosis.
María Virginia Gentilini, Guillermo Hernán Giambartolomei, María Victoria Delpino   +2 more
doaj   +1 more source

SYNOVIOCYTES BUT NOT ARTICULAR CHONDROCYTES RELEASE FREE RADICALS AFTER REPETITIVE CYCLES OF ANOXIA/REOXYGENATION: AN ELECTRON SPIN RESONANCE STUDY.

, 2005
Objective : We investigated if short recurrent periods of anoxia/reoxygenation (A/R), mimicking the in vivo conditions of hypoxia, could stimulate the production of free radicals by synoviocytes and chondrocytes.
Schneider, Nicole, Lejeune, Jean-Philippe, Mouithys-Mickalad, Ange, Deby-Dupont, Ginette, Serteyn, Didier   +4 more
core   +1 more source

PO:01:014 | Differential inflammatory responses of CD14+ and CD14– synoviocytes in psoriatic arthritis: implications for pathogenesis and targeted therapies

Reumatismo
Background. Investigating the inflammatory response of synoviocytes in patients with psoriatic arthritis (PsA) is crucial due to their central role in disease pathogenesis. Recent studies have reported upregulation of interleukin-6 (IL-6) and activation
Società Italiana di Reumatologia
doaj  

Synoviocytes assist in modulating the effect of Ross River virus infection in micromass-cultured primary human chondrocytes

Introduction. Ross River virus (RRV) is a mosquito-borne virus prevalent in Australia and the islands of the South Pacific, where it causes an arthritogenic illness with a hallmark feature of severe joint pain.
Lim, Elisa XY, Freppel, Wesley, Herrero, Lara J, Rudd, Penny A   +3 more
core   +1 more source