Results 91 to 100 of about 19,285 (227)

Radiosynoviorthesis and Its Effectiveness: Brazilian Experience in 1136 Joints of 572 Patients With Hemophilic Arthropathy

Haemophilia, EarlyView.
ABSTRACT Introduction Synovium plays a central role in the development of haemophilic arthropathy (HA). Minimally invasive treatments for haemophilic synovitis are better options than surgery and radiosynoviorthesis (RSO) is considered the treatment of choice. Objective To evaluate the main factors that influenced the results of RSO in HA.
Vanessa Giroto Guedes, Sylvia Thomas, Edison Iglesias de Oliveira Vidal, Marcelo Tavella Navega, Flávia Martins Costa, Clarissa Canella, Fernando Eduardo Zikan, Sergio Augusto Lopes de Souza   +7 more
wiley   +1 more source

Ontology and Function of Fibroblast-Like and Macrophage-Like Synoviocytes: How Do They Talk to Each Other and Can They Be Targeted for Rheumatoid Arthritis Therapy?

Frontiers in Immunology, 2018
Fibroblast-like synoviocytes (FLS) and macrophage-like synoviocytes (MLS) are the two main cellular components of the synovium. It has been widely reported that FLS and MLS play essential roles in the joint pathology of rheumatoid arthritis (RA ...
Jiajie Tu, Wenming Hong, Wenming Hong, Pengying Zhang, Xinming Wang, Xinming Wang, Heinrich Körner, Wei Wei   +7 more
doaj   +1 more source

Fibroblast-like synoviocytes dependent terminal differentiation of naïve B cells is inhibited compared to IgD+ memory B cells

, 2023
Data used for the manuiscript "Fibroblast-like synoviocytes dependent terminal differentiation of naïve B cells is inhibited compared to IgD+ memory B cells". Tables are formated as CSV files.
Dennis Bleck (6705434)
core   +1 more source

Chikungunya virus uses the tetraspanins CD63, CD9, and CD151 to replicate in human synovial fibroblasts

Cell Reports
Summary: The arthritogenic alphavirus chikungunya virus (CHIKV) causes debilitating long-lasting joint pain. Host factors used by CHIKV to infect joint cells are largely unknown.
Eve K. Brown, Cora Stegmann, Hannah Biermann, Verena Pittl, Mara Duven, Anja C.M. de Bruin, Elena Neumann, Gisa Gerold   +7 more
doaj   +1 more source

Krüppel-Like Factor 4 Is a Regulator of Proinflammatory Signaling in Fibroblast-Like Synoviocytes through Increased IL-6 Expression

Mediators of Inflammation, 2016
Human fibroblast-like synoviocytes play a vital role in joint synovial inflammation in rheumatoid arthritis (RA). Proinflammatory cytokines induce fibroblast-like synoviocyte activation and dysfunction.
Xinjing Luo, Jie Chen, Jianwei Ruan, Yongfeng Chen, Xuanrong Mo, Jiangwen Xie, Guoju Lv   +6 more
doaj   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

Decreased tubulin synthesis in synoviocytes from adjuvant-induced arthritic rats

, 1992
The first microscopical alterations along adjuvant arthritis induction in rats seem to appear in the synovium. We have studied the protein synthesis pattern of the cells constitutively present in synovial membrane (synoviocytes) and have found an ...
Ramos-Ruiz, Ricardo, Larraga, Vicente, Ávila, Jesús, López-Bote, Juan P., Bernabéu, Carmelo   +4 more
core   +1 more source

Effect of diclofenac etalhyaluronate (SI-613) on the production of high molecular weight sodium hyaluronate in human synoviocytes

BMC Musculoskeletal Disorders, 2019
Background We have reported that a single intra-articular injection of diclofenac etalhyaluronate (SI-613) exerted a potent and long-lasting analgesic effect in experimental arthritis models.
Tomochika Kisukeda, Junichi Onaya, Keiji Yoshioka   +2 more
doaj   +1 more source

Emerging Roles of PSTPIP2 in Autoimmunity: From Mechanism to Therapeutic Implications

Immunology, Volume 179, Issue 4, Page 565-578, December 2026.
PSTPIP2 acts as a key brake on myeloid inflammation by suppressing IL‐1β‐driven signalling, macrophage dysregulation and inflammation‐associated bone remodelling. Its emerging roles in CRMO/CMO, rheumatoid arthritis, SAPHO syndrome and bullous pemphigoid support its potential as a biomarker and therapeutic target.
Erdong Zhang, Fengyu Liu, Yongle Wei, Guoqiang Li, Liujie Zheng, Lin Jin, Feng Luan, Yingze Zhang, Ling Wang, Zhiyong Hou   +9 more
wiley   +1 more source

Does Platelet-Rich Plasma Freeze-Thawing Influence Growth Factor Release and Their Effects on Chondrocytes and Synoviocytes? [PDF]

, 2014
PRP cryopreservation remains a controversial point. Our purpose was to investigate the effect of freezing/thawing on PRP molecule release, and its effects on the metabolism of chondrocytes and synoviocytes. PRP was prepared from 10 volunteers, and a half
ROFFI, ALICE, ASSIRELLI, ELISA, MARIANI, ERMINIA, Annarita Cenacchi, Lia Pulsatelli, FILARDO, GIUSEPPE, Facchini, A., Andrea Facchini, Erminia Mariani, Cavallo, C., Pulsatelli, L., Carola Cavallo, KON, ELIZAVETA, Cenacchi, A., Elisa Assirelli, Alice Roffi, Loredana Pratelli, Brunella Grigolo, GRIGOLO, BRUNELLA, Elizaveta Kon, Maurilio Marcacci, MARCACCI, MAURILIO, Giuseppe Filardo, Pratelli, L.   +23 more
core   +1 more source