Results 11 to 20 of about 58,561 (288)

The stressed synovium [PDF]

open access: yesArthritis Research & Therapy, 2001
This review focuses on the mechanisms of stress response in the synovial tissue of rheumatoid arthritis. The major stress factors, such as heat stress, shear stress, proinflammatory cytokines and oxidative stress, are discussed and reviewed, focusing on their potential to induce a stress response in the synovial tissue.
Schett, Georg   +3 more
openaire   +2 more sources

Chondrosarcomas of the synovium [PDF]

open access: yesCancer, 1991
Chondrosarcoma of the synovium, either primary or secondary to synovial chondromatosis, is rare. Ten cases of synovial chondrosarcoma were studied (four from the Mayo Clinic files and six from the authors' consultation files). Two were considered primary.
F, Bertoni   +3 more
openaire   +2 more sources

Bridging Insights From Lymph Node and Synovium Studies in Early Rheumatoid Arthritis

open access: yesFrontiers in Medicine, 2022
Rheumatoid arthritis (RA) is a chronic autoimmune disease of unknown etiology characterized by inflammation of the peripheral synovial joints leading to pannus formation and bone destruction.
Aoife M. O'Byrne   +8 more
doaj   +1 more source

In Vivo Fluorescence Imaging of E-Selectin: Quantitative Detection of Endothelial Activation in Arthritis [PDF]

open access: yes, 2010
Rheumatoid arthritis (RA) is a chronic progressive systemic inflammatory disease, characterized by synovial inflammation and localized destruction of cartilage and bone.
Gompels, Luke, Gompels, Luke
core   +1 more source

Immunopathogenesis of rheumatoid arthritis [PDF]

open access: yes, 2017
Rheumatoid arthritis (RA) is the most common inflammatory arthropathy. The majority of evidence, derived from genetics, tissue analyses, models, and clinical studies, points to an immune-mediated etiology associated with stromal tissue dysregulation that
Ahmed   +115 more
core   +1 more source

The Normal Synovium [PDF]

open access: yesThe Open Rheumatology Journal, 2011
This paper describes the structure and function of the normal synovium including the cellular content, nerve and vascular supply and how normal synovium maintains homeostasis within the joint. It is important to understand normal synovium before appreciating the changes that occur in the synovial membrane which leads to the pathology seen in ...
openaire   +2 more sources

Distribution of Neuropeptides in the Synovium of Charcot Neuroarthropathy

open access: yesFoot & Ankle Orthopaedics, 2016
Category: Basic Sciences/Biologics Introduction/Purpose: The pathology of Charcot neuroarthropathy (CNA) presents inflammation, and bone and cartilage destruction. It is still unclear how the neuropathic signals lead to joint inflammation and destruction.
Lew C. Schon MD   +3 more
doaj   +1 more source

New Developments in Transcriptomic Analysis of Synovial Tissue

open access: yesFrontiers in Medicine, 2020
Transcriptomic technologies are constantly changing and improving, resulting in an ever increasing understanding of gene expression in health and disease.
Hayley L. Carr   +5 more
doaj   +1 more source

Interplay Between Iron Overload and Osteoarthritis: Clinical Significance and Cellular Mechanisms

open access: yesFrontiers in Cell and Developmental Biology, 2022
There are multiple diseases or conditions such as hereditary hemochromatosis, hemophilia, thalassemia, sickle cell disease, aging, and estrogen deficiency that can cause iron overload in the human body.
Chenhui Cai, Wenhui Hu, Tongwei Chu
doaj   +1 more source

Driving chronicity in rheumatoid arthritis: perpetuating role of myeloid cells [PDF]

open access: yes, 2018
Acute inflammation is a complex and tightly regulated homeostatic process that includes leukocyte migration from the vasculature into tissues to eliminate the pathogen/injury, followed by a pro-resolving response promoting tissue repair.
Achuthan   +115 more
core   +1 more source

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