Results 31 to 40 of about 58,561 (288)
Elevated ACKR2 expression is a common feature of inflammatory arthropathies [PDF]
, 2017 Objectives. Chemokines are essential contributors to leucocyte accumulation at sites of inflammatory pathology. Interfering with chemokine or chemokine receptor function therefore represents a plausible therapeutic option.
Baldwin, Helen M. +6 more
core +1 more source
The Synovium in Rheumatoid Arthritis [PDF]
The Open Rheumatology Journal, 2011 Rheumatoid arthritis (RA) is a chronic autoimmune disease targeting multiple joints. The synovium is the primary site of the inflammatory process, which if untreated leads to irreversible damage to the adjacent cartilage and bone. It is now well established that autoantibodies that are characteristic of RA, including rheumatoid factor (RF) and anti ...
Hitchon, Carol A, El-Gabalawy, Hani S
openaire +2 more sources
Pathology of the Synovium [PDF]
American Journal of Clinical Pathology, 2000 Synovium is specialized mesenchymal tissue that is essential for the appropriate function of the locomotor apparatus. It is the site for a series of pathologic processes that are characteristic, and in some cases specific, to this distinctive tissue. In this article, the normal microscopic anatomy of synovium is briefly reviewed. Synovial proliferative
openaire +2 more sources
Cells, 2019 rs26232, located in intron one of C5orf30, is associated with the susceptibility to and severity of rheumatoid arthritis (RA). Here, we investigate the relationship between this variant and the biological activities of rheumatoid arthritis synovial ...
Emma R Dorris +5 more
doaj +1 more source
Who drives the progress of osteoarthritis? – A descriptive study of synovium-meniscus crosstalk
European Cells & MaterialsObjective: The incidence of osteoarthritis (OA) increases with each passing year. The degeneration of the meniscus and synovium is considered the initial factor of knee osteoarthritis (KOA), but their synergistic mechanism has not been clarified. Methods:
F Yu +8 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2019 Articular cartilage damaged through trauma or disease has a limited ability to repair. Untreated, focal lesions progress to generalized changes including osteoarthritis.
Kendrick To +4 more
doaj +1 more source
Quantitative assessment of angiogenesis in murine antigen-induced arthritis by intravital fluorescence microscopy [PDF]
, 2003 Inhibition of angiogenesis might be a therapeutic approach to prevent joint destruction caused by the overgrowing synovial tissue during chronic joint inflammation.
Krombach, F. +7 more
core +1 more source
Radiological findings of Secondary Synovial Chondromatosis of Elbow Joint: A Case Report [PDF]
Journal of Clinical and Diagnostic ResearchSynovial Chondromatosis (SC), previously known as synovial osteochondromatosis, is usually an uncommonly encountered condition. Pathologically, the condition involves the formation of multiple cartilaginous nodules that arise from the synovium of facet ...
Pulkit Kumar Santoshi +2 more
doaj +1 more source
A Rare Case of Hip Pain Secondary to Pigmented Villonodular Synovitis [PDF]
, 2020 A 19-year-old Asian male presented to our emergency department with atraumatic right hip pain radiating to the right groin associated with pain on ambulation.
Ganguly, Bhaskar +4 more
core
Alterations in the self-renewal and differentiation ability of bone marrow mesenchymal stem cells in a mouse model of rheumatoid arthritis [PDF]
, 2010 Introduction: Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease primarily involving the synovium. Evidence in recent years has suggested that the bone marrow (BM) may be involved, and may even be the initiating site of the disease ...
Bellantuono, I. +8 more
core +3 more sources