Results 61 to 70 of about 46,398 (238)
Medicinal Research Reviews, EarlyView.ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley +1 more source
, 2019 Conserved syntenic regions among publicly available cotton genomes were analyzed by CottonGen and made available using the Tripal Synteny Viewer developed by the Fei Bioinformatics Lab from the Boyce Thomson Institute at Cornell University.
Taein Lee (17478699) +7 more
core +1 more source
Synteny Blocks between Human and Mouse X Chromosomes
, 2013 Blocks for the X chromosomes were constructed by GRIMM-Synteny (blue) based on anchor coordinates and ST-Synteny (red) based only on anchor permutations. Anchors are shown in green. Small blocks deleted by ST-Synteny are shown in black.
Pavel A Pevzner (16055) +2 more
core +1 more source
Comparative Analysis of Stress Adaptation in the Yeast Microbiome of Cactus
Yeast, EarlyView.Yeasts and related fungi isolated from cacti or nearby non‐cactus plants were characterized phenotypically and genomically, revealing differences that hint at modes of adaptation to the cactus host. ABSTRACT Together with other fungi, yeasts make up a significant component of the plant microbiome. As the planet warms, cacti expand their range.
Alya N. Hussain +2 more
wiley +1 more source
Synteny analysis of JAK family members.
, 2012 Synteny analysis of the relevant zebrafish and human JAK gene loci (white), indicating adjacent genes in their respective orientations. Genes showing conserved synteny between zebrafish and human are in black, genes which have homologues displaying ...
Monique C. Trengove (179783) +3 more
core +1 more source
Insect Science, EarlyView.The mitogenome was transcribed into complete primary polycistrons on both strands. The heteropteran mitochondrial transcription termination factor (HmTTF) functions as a bidirectional attenuator rather than a terminator, and co‐evolution of HmTTF and the binding sites was observed.
Shiwen Xu +6 more
wiley +1 more source
Hox Gene Variation Drives Morphological Specialization of Humpback Grouper Cromileptes altivelis
Integrative Zoology, EarlyView.Cromileptes altivelis exhibits a distinctive “sunken head and humpback” morphology, formed through cranial remodeling. Genetic analyses identified unique amino acid variants in Hoxa7a and Hoxa10b, with functional tests confirming their role in enhancing osteoblast activity and driving cranial remodeling.
Xiaoying Cao +4 more
wiley +1 more source
Asymmetric Treatment of Genomes by ST-Synteny
, 2013 In comparing two genomes, ST-Synteny may produce different synteny blocks depending on which one is chosen as the reference genome. The synteny blocks produced by ST-Synteny are shown as red boxes around the anchors.(A) The genome shown on the y-axis is ...
Pavel A Pevzner (16055) +2 more
core +1 more source
High precision detection of conserved segments from synteny blocks. [PDF]
, 2017 A conserved segment, i.e. a segment of chromosome unbroken during evolution, is an important operational concept in comparative genomics. Until now, algorithms that are designed to identify conserved segments often return synteny blocks that overlap ...
Joseph Mex Lucas +3 more
core +1 more source
Integrative Zoology, EarlyView.This study presents the first genomic identification and characterization of ZW sex chromosomes in two soft‐shelled turtle species through genome assembly and resequencing. We reveal the structural organization of ZW chromosomes, identifying both pseudoautosomal regions (PARs) and differentiated regions.
Jianjun Liu +9 more
wiley +1 more source